Abstract
iRefIndex provides an index of protein interactions available in a number of primary interaction databases. This index allows the user to search for a protein and retrieve a non-redundant list of interactors for that protein.
This system uses the Redundant Object Group (ROG) and Redundant Interaction Group (RIG) identifier to group proteins and interactions into redundant groups. This method allows users to integrate their own data with the iRefIndex in a way that ensures proteins with the exact same sequence and NCBI taxonomy identifier will be represented only once.
iRefIndex has consolidated 10 different interaction databases using this method and provides a number of methods to access these data. This includes downloading as PSI-MI compliant tab-delimited file and from the iRefScape plugin for (http://www.cytoscape.org/), PSICQUIC web services and the iRefWeb(http://wodaklab.org/iRefWeb/).
More details about iRefIndex and links available at: http://irefindex.uio.no/wiki/iRefIndex