Browsing BioMed Central høstingsarkiv by Author "Zucknick, Manuela"
Now showing items 1-11 of 11
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Nustad, Haakon E; Page, Christian M; Reiner, Andrew H; Zucknick, Manuela; LeBlanc, Marissa (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background A Bayesian mixed model approach using integrated nested Laplace approximations (INLA) allows us to construct flexible models that can account for pedigree structure. Using these models, we estimate ...
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Combining heterogeneous subgroups with graph-structured variable selection priors for Cox regression Madjar, Katrin; Zucknick, Manuela; Ickstadt, Katja; Rahnenführer, Jörg (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background Important objectives in cancer research are the prediction of a patient’s risk based on molecular measurements such as gene expression data and the identification of new prognostic biomarkers ...
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Rønneberg, Leiv; Kirk, Paul D. W.; Zucknick, Manuela (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)In this paper we propose PIICM, a probabilistic framework for dose–response prediction in high-throughput drug combination datasets. PIICM utilizes a permutation invariant version of the intrinsic co-regionalization model ...
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Degnes, Maren-Helene L.; Westerberg, Ane C.; Zucknick, Manuela; Powell, Theresa L.; Jansson, Thomas; Henriksen, Tore; Roland, Marie C. P.; Michelsen, Trond M. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Background Placenta-derived proteins in the systemic maternal circulation are suggested as potential biomarkers for placental function. However, the identity and longitudinal patterns of such proteins are ...
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Schellhorn, Till; Zucknick, Manuela; Askim, Torunn; Munthe-Kaas, Ragnhild; Ihle-Hansen, Hege; Seljeseth, Yngve M.; Knapskog, Anne-Brita; Næss, Halvor; Ellekjær, Hanne; Thingstad, Pernille; Wyller, Torgeir B.; Saltvedt, Ingvild; Beyer, Mona K. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background Chronic brain pathology and pre-stroke cognitive impairment (PCI) is predictive of post-stroke dementia. The aim of the current study was to measure pre-stroke neurodegenerative and vascular ...
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Schmutz, Maximilian; Zucknick, Manuela; Schlenk, Richard F.; Mertens, Daniel; Benner, Axel; Weichenhan, Dieter; Mücke, Oliver; Döhner, Konstanze; Plass, Christoph; Bullinger, Lars; Claus, Rainer (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Background Acute myeloid leukemia (AML) is a heterogeneous disease with a poor prognosis. Dysregulation of the epigenetic machinery is a significant contributor to disease development. Some AML patients ...
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Mørk, Marianne; Hoksrud, Aasne F.; Soberg, Helene L.; Zucknick, Manuela; Heide, Marte; Groven, Karen S.; Røe, Cecilie (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Background Foot disorders affect up to one quarter of the adult population. Plantar fasciopathy is a common cause of foot pain associated with decreased activity level and quality of life. Patient-reported ...
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LeBlanc, Marissa; Nustad, Haakon E; Zucknick, Manuela; Page, Christian M (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background An important feature in many genomic studies is quality control and normalization. This is particularly important when analyzing epigenetic data, where the process of obtaining measurements can ...
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Hjelle, Ellen G; Bragstad, Line K; Zucknick, Manuela; Kirkevold, Marit; Thommessen, Bente; Sveen, Unni (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background Several studies have documented the variety of post-stroke psychosocial challenges, which are complex, multifaceted, and affect a patient’s rehabilitation and recovery. Due to the consequences ...
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Henriksen, Hege B; Ræder, Hanna; Bøhn, Siv K; Paur, Ingvild; Kværner, Ane S; Billington, Siv Å; Eriksen, Morten T; Wiedsvang, Gro; Erlund, Iris; Færden, Arne; Veierød, Marit B; Zucknick, Manuela; Smeland, Sigbjørn; Blomhoff, Rune (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background Colorectal cancer survivors are not only at risk for recurrent disease but also at increased risk of comorbidities such as other cancers, cardiovascular disease, diabetes, hypertension and ...
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Henriksen, Hege B; Berntsen, Sveinung; Paur, Ingvild; Zucknick, Manuela; Skjetne, Anne J; Bøhn, Siv K; Henriksen, Christine; Smeland, Sigbjørn; Carlsen, Monica H; Blomhoff, Rune (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background In order to investigate the impact of adherence to recommendations of physical activity and sedentary time on health outcomes in clinical trials, there is a need for feasible tools such as ...