Browsing BioMed Central høstingsarkiv by Author "Vos, Stephanie"

Now showing items 1-3 of 3

  • APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer’s disease 
    Konijnenberg, Elles; Tijms, Betty M; Gobom, Johan; Dobricic, Valerija; Bos, Isabelle; Vos, Stephanie; Tsolaki, Magda; Verhey, Frans; Popp, Julius; Martinez-Lage, Pablo; Vandenberghe, Rik; Lleó, Alberto; Frölich, Lutz; Lovestone, Simon; Streffer, Johannes; Bertram, Lars; Blennow, Kaj; Teunissen, Charlotte E; Veerhuis, Robert; Smit, August B; Scheltens, Philip; Zetterberg, Henrik; Visser, Pieter J (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background Aggregation of amyloid β into plaques in the brain is one of the earliest pathological events in Alzheimer’s disease (AD). The exact pathophysiology leading to dementia is still uncertain, but the apolipoprotein ...
  • Multivariate GWAS of Alzheimer’s disease CSF biomarker profiles implies GRIN2D in synaptic functioning 
    Neumann, Alexander; Ohlei, Olena; Küçükali, Fahri; Bos, Isabelle J.; Timsina, Jigyasha; Vos, Stephanie; Prokopenko, Dmitry; Tijms, Betty M.; Andreasson, Ulf; Blennow, Kaj; Vandenberghe, Rik; Scheltens, Philip; Teunissen, Charlotte E.; Engelborghs, Sebastiaan; Frisoni, Giovanni B.; Blin, Oliver; Richardson, Jill C.; Bordet, Régis; Lleó, Alberto; Alcolea, Daniel; Popp, Julius; Marsh, Thomas W.; Gorijala, Priyanka; Clark, Christopher; Peyratout, Gwendoline; Martinez-Lage, Pablo; Tainta, Mikel; Dobson, Richard J. B.; Legido-Quigley, Cristina; Van Broeckhoven, Christine; Tanzi, Rudolph E.; ten Kate, Mara; Lill, Christina M.; Barkhof, Frederik; Cruchaga, Carlos; Lovestone, Simon; Streffer, Johannes; Zetterberg, Henrik; Visser, Pieter J.; Sleegers, Kristel; Bertram, Lars (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background Genome-wide association studies (GWAS) of Alzheimer’s disease (AD) have identified several risk loci, but many remain unknown. Cerebrospinal fluid (CSF) biomarkers may aid in gene discovery and ...
  • The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics 
    Bos, Isabelle; Vos, Stephanie; Vandenberghe, Rik; Scheltens, Philip; Engelborghs, Sebastiaan; Frisoni, Giovanni; Molinuevo, José L; Wallin, Anders; Lleó, Alberto; Popp, Julius; Martinez-Lage, Pablo; Baird, Alison; Dobson, Richard; Legido-Quigley, Cristina; Sleegers, Kristel; Van Broeckhoven, Christine; Bertram, Lars; ten Kate, Mara; Barkhof, Frederik; Zetterberg, Henrik; Lovestone, Simon; Streffer, Johannes; Visser, Pieter J (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background There is an urgent need for novel, noninvasive biomarkers to diagnose Alzheimer’s disease (AD) in the predementia stages and to predict the rate of decline. Therefore, we set up the European ...