Browsing BioMed Central høstingsarkiv by Author "Iversen, Nina"
Now showing items 1-7 of 7
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Stavik, Benedicte; Skretting, Grethe; Aasheim, Hans-Christian; Tinholt, Mari; Zernichow, Lillian; Sletten, Marit; Morten Sandset, Per; Iversen, Nina (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background Increased hemostatic activity is common in many cancer types and often causes additional complications and even death. Circumstantial evidence suggests that tissue factor pathway inhibitor-1 ...
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Dahm, Anders E; Iversen, Nina; Birkenes, Baard; Ree, Anne H; Sandset, Per M (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)Background Hormone therapy, oral contraceptives, and tamoxifen increase the risk of thrombotic disease. These compounds also reduce plasma content of tissue factor pathway inhibitor-1 (TFPI), which is the ...
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Tjeldhorn, Lena; Iversen, Nina; Sandvig, Kirsten; Bergan, Jonas; Sandset, Per M; Skretting, Grethe (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background Activated protein C (PC) is a serine protease that regulates blood coagulation by inactivating coagulation factors Va and VIIIa. PC deficiency is an autosomally inherited disorder associated with ...
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Tinholt, Mari; Viken, Marte K; Dahm, Anders E; Vollan, Hans K M; Sahlberg, Kristine K; Garred, Øystein; Børresen-Dale, Anne-Lise; Jacobsen, Anne F; Kristensen, Vessela; Bukholm, Ida; Kåresen, Rolf; Schlichting, Ellen; Skretting, Grethe; Lie, Benedicte A; Sandset, Per M; Iversen, Nina (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Background The procoagulant state in cancer increases the thrombotic risk, but also supports tumor progression. To investigate the molecular mechanisms controlling cancer and hemostasis, we conducted a ...
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Stavik, Benedicte; Tinholt, Mari; Sletten, Marit; Skretting, Grethe; Sandset, Per M; Iversen, Nina (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)Background Tissue factor (TF) pathway inhibitor-1 (TFPI) is expressed in several malignant tissues- and cell lines and we recently reported that it possesses anti-tumor effects in breast cancer cells, ...
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Chollet, Maria E; Skarpen, Ellen; Iversen, Nina; Sandset, Per M; Skretting, Grethe (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Some inherited coagulation factor deficiencies are caused by intracellular retention or degradation of misfolded proteins, and chemical chaperones have been shown to reverse protein misfolding. The purpose of the present ...
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Tinholt, Mari; Vollan, Hans K M; Sahlberg, Kristine K; Jernström, Sandra; Kaveh, Fatemeh; Lingjærde, Ole C; Kåresen, Rolf; Sauer, Torill; Kristensen, Vessela; Børresen-Dale, Anne-Lise; Sandset, Per M; Iversen, Nina (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Introduction Hypercoagulability in malignancy increases the risk of thrombosis, but is also involved in cancer progression. Experimental studies suggest that tissue factor (TF) and tissue factor pathway ...