Browsing BioMed Central høstingsarkiv by Title
Now showing items 1453-1472 of 3217
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background Inappropriate antibiotic prescribing, particularly for respiratory tract infections (RTI) in ambulatory care, has become a worldwide public health threat due to resulting antibiotic resistance. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)Backgound In scrapie and prion diseases, the knowledge concerning genes involved in host response during the early infection period in the lymphoid tissues, still remains limited. In the present study, we ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background Until recently, chromosomal translocations and fusion genes have been an underappreciated class of mutations in solid tumors. Next-generation sequencing technologies provide an opportunity for ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background The genetic mechanisms for families who meet the clinical criteria for Lynch syndrome (LS) but do not carry pathogenic variants in the mismatch repair (MMR) genes are still undetermined. We aimed ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Background A deep understanding of carcinogenesis at the DNA level underpins many advances in cancer prevention and treatment. Mutational signatures provide a breakthrough conceptualisation, as well as an ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background The work of the FANTOM5 Consortium has brought forth a new level of understanding of the regulation of gene transcription and the cellular processes involved in creating diversity of cell types. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)Background MADS-domain transcription factors play important roles during plant development. The Arabidopsis MADS-box gene SHORT VEGETATIVE PHASE (SVP) is a key regulator of two developmental phases. It ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background There is a long-lasting need for non-invasive, more accurate diagnostic techniques when evaluating primary Sjögren’s syndrome (pSS) patients. Incorporation of additional diagnostics involving ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background Surface proteins are a key to a deeper understanding of the behaviour of Gram-positive bacteria interacting with the human gastro-intestinal tract. Such proteins contribute to cell wall synthesis ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background The HMGA2 gene, coding for an architectural transcription factor involved in mesenchymal embryogenesis, is frequently deranged by translocation and/or amplification in mesenchymal tumours, generally ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)Background Two main genes encoding the catalytic subunits Cα and Cβ of cyclic AMP dependent protein kinase (PKA) have been identified in all vertebrates examined. The murine, bovine and human Cβ genes encode ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Background A healthy diet can decrease the risk of several lifestyle diseases. From studying the health effects of single foods, research now focuses on examining complete diets and dietary patterns ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background With the recent advances and availability of various high-throughput sequencing technologies, data on many molecular aspects, such as gene regulation, chromatin dynamics, and the three-dimensional ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Background It is of great importance to identify molecular processes and pathways that are involved in disease etiology. Although there has been an extensive use of various high-throughput methods for this ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)The concept of school climate has received much attention as a predictor of educational outcomes, including students’ well-being, academic achievement, and motivation. To measure this concept, international large-scale ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Background In order to change antibiotic prescribing behaviour, we need to understand the prescribing process. The aim of this study was to identify targets for antibiotic stewardship interventions in ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background There is still no worldwide agreement on the best diagnostic thresholds to define gestational diabetes (GDM) or the optimal approach for identifying women with GDM. Should all pregnant women ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Background Motivational negative symptoms hinder quality of life and daily functioning of individuals with schizophrenia spectrum disorders. A recently developed intervention, Switch, has shown promising effects on negative ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background Several inflammatory molecules participate in the immune response to malaria. Interleukin (IL)-18 is an inflammatory cytokine activated by NLRP3 inflammasomes. In clinical falciparum malaria, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background Patients with chest pain or palpitations often have poor outcomes following a negative cardiac evaluation, with symptom persistence, limitations in everyday activities, and reduced health-related ...