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(Master thesis / Masteroppgave, 2005)
Prostate cancer (PCa) and obesity are currently two of the most prevalent health problems in the western world. Some epidemiological studies suggest a connection between PCa and fat intake and obesity. In addition, androgens, ...
(Master thesis / Masteroppgave, 2007)
Identifikasjonen av proteinet hNCU-G1 er basert på interaksjonen med hCRBP1-promoterens FP1-element (+66-+99), som ble gjort ved EMSA-studier. Videre studier avslørte at hNCU-G1 kunne fungere som en transkripsjonsfaktor ...
(Master thesis / Masteroppgave, 2005)
Androgen ablation during the initial stages of prostate cancer causes regression of the tumor due to an increase in apoptosis and reduced cellular proliferation. However, some prostate cancer cells survive in the androgen ...
(Master thesis / Masteroppgave, 2011)
Genetisk og funksjonell studie av glykosyltransferase PglA i Neisseria gonorrhoeae og Neisseria lactamica Restricted Access
(Master thesis / Masteroppgave, 2010)
Neisseria er en gruppe gram-negative bakterier som består av både patogene og ikke-patogene arter. Patogene Neisseria fører til store helseproblemer på verdensbasis; Neisseria meningitidis kan forårsake meningokokksykdom, ...
(Master thesis / Masteroppgave, 2009)
Malignant melanoma is a very metastatic and therapy resistant disease, with few therapeutic options in advanced stages. An abnormal apoptosis pathway is considered to contribute substantially to the resistance observed in ...
(Master thesis / Masteroppgave, 2006)
It has previously been found that the sequence and conformation of a 10-nucleotide element in the 5´untranslated region (5´UTR) of rbcL mRNA are important for transcript stability. In this study two variants of a 20-nucleotide ...
PTM-crosstalk in c-Myb : Analysis of interdependence between posttranslational modifications in the negative regulatory domain of the oncoprotein c-Myb. Restricted Access
(Master thesis / Masteroppgave, 2009)
Heterolog ekspresjon av immunitetsproteinet til to-peptidbakteriosinet lactococcin G Restricted Access
(Master thesis / Masteroppgave, 2009)
Bakteriosiner er ribosomalt syntetiserte, antimikrobielle peptider som produseres av en rekke bakteriearter. Lactococcin G er et bakteriosin som består av to peptider, kalt α og β, og produseres av melkesyrebakterien ...
(Master thesis / Masteroppgave, 2008)
Epitelcellelinjen ”Madin-Darby canine kidney (MDCK)” er en velstudert polarisert cellelinje som danner tette cellelag med separate apikale og basolaterale membrandoméner. Proteoglykaner sorteres til både den apikale og den ...
(Master thesis / Masteroppgave, 2008)
Crucian carp (Carassius carassius) avoids lactic acidosis during prolonged periods of anoxia by producing ethanol as the main anaerobic end-product. Apparently, this is made possible by adaptations in the pyruvate dehydrogenase ...
(Master thesis / Masteroppgave, 2009)
High levels of oxidative stress are a common aspect of most neurodegenerative disorders. Oxidative stress in the brain causes DNA lesions that are mainly repaired by the base excision repair (BER) pathway. The BER pathway ...
Targeted delivery of resurfaced gp120 to antigen-presenting cells, a novel vaccine concept in HIV vaccine development Restricted Access
(Master thesis / Masteroppgave, 2011)
DNA vaccines have the ability to induce humoral and cellular immune responses but their efficiency needs further improvement. One strategy is to target the antigen to surface receptors on antigen-presenting cells (APCs), ...
DAXX-dependent recruitment of the histone variant H3.3 to PML bodies prior to chromatin deposition Restricted Access
(Master thesis / Masteroppgave, 2012)
The genome is organized into chromatin domains which can be distinguished by enrichment in post-translational modifications of histones and histone variants. Since the histone code has been discovered, little is known about ...
(Master thesis / Masteroppgave, 2011)
Epitelcellelinjen ”Madin-Darby canine kidney” (MDCK) er en velstudert polarisert cellelinje som danner tette cellelag med separate apikale og basolaterale membrandomener, som ved hjelp av polarisert transport av nysyntetiserte ...
Functional Analysis of Kallikrein 4 in LNCaP cells Restricted Access
(Master thesis / Masteroppgave, 2009)
Prostate cancer is one of the most frequently diagnosed cancers and second highest cause of death in patients who suffer from cancer in western countries. Much effort has been carried out to understand the molecular ...
Functional characterization of a novel human methyltransferase and the generation of corresponding knockout human cell lines Restricted Access
(Master thesis / Masteroppgave, 2010)
This study investigates the function of a novel human protein, which, based on secondary structure prediction, belongs to class I of SAM-dependent methyltransferases (MTases). No specific functions or substrates have yet ...
Targeting Epidermal Growth Factor Receptor 2 in Carcinogenesis Restricted Access
(Master thesis / Masteroppgave, 2009)
Nearly all human tissues express epidermal growth factor receptors(ErbBs)embedded in the plasma membrane. Four homologous ErbB proteins exert a pivotal function of transmitting proliferative signals by binding their cognate ...
(Master thesis / Masteroppgave, 2007)
Human bone marrow multipotent mesenchymal stromal cells (hBM-MSC) represent an appealing source of adult stem cells for cell therapy and tissue engineering. Since hBM-MSC are present at low frequency in the bone marrow, ...
(Master thesis / Masteroppgave, 2012)
At the moment, one-third of the world’s population is estimated to be infected with Mycobacterium tuberculosis (M.tb), the causative agent of tuberculosis (TB) in humans. Our treatment strategies have been greatly challenged ...
Human Endonuclease V - Cloning, Expression, Purification and Biochemical Characterization Restricted Access
(Master thesis / Masteroppgave, 2011)
Multiple DNA damaging agents cause deaminations of the bases of DNA. If not repaired, these can lead to mutations, which in turn can result in dangerous diseases. Endonuclease V (EndoV) is a highly conserved gene from ...
(Master thesis / Masteroppgave, 2008)
The crucian carp (Carassius carassius) inhabits lakes and ponds in Northern Europe, where it is able to survive anoxia that often occurs for months during the long winter. Several physiological adaptations, including the ...
(Master thesis / Masteroppgave, 2011)
Gb3 (Gal α1-4, Gal β1-4, Glc β1-1, Ceramide) is a neutral glycosphingolipid specifically expressed in several human tissues, and is recognised as a receptor for Shiga toxins. Gb3 has been demonstrated to be upregulated in ...
Towards the development of nanobead vaccines against salmon pathogens: : establishment of cold-water fish infection models Restricted Access
(Master thesis / Masteroppgave, 2011)
As the fish farming industry is growing all over the world, economic losses caused by diseases are also increasing. In Norway one fifth of the farmed fish are lost due to viral diseases; there is no treatment for viral ...
(Master thesis / Masteroppgave, 2005)
ABSTRACT
The aim of this thesis was to investigate the in vitro physiological and genetic responses of Bacillus cereus ATCC 14579 to bile, bile salts and mucin, substances which would be encountered in the gastrointestinal ...
(Master thesis / Masteroppgave, 2008)
Animals store most excess energy as fat in specialized cells called adipocytes which form the major part of adipose tissue. Since obesity, which has reached epidemic proportions in the last decades, is the result of excess ...
Optimization of a cell free protein synthesis system for expression of Lactococcin A immunity protein Restricted Access
(Master thesis / Masteroppgave, 2012)
Design of an inducible system to control SUMOylation of the transcription factor c-Myb in vivo Restricted Access
(Master thesis / Masteroppgave, 2010)
The transcription factor c-Myb is an important regulator involved in proliferation, differentiation, and apoptosis of hematopoietic cells. Its activity is regulated through interactions with co-repressors and co-activators. ...
(Master thesis / Masteroppgave, 2005)
Abstract
The intention of this study was to identify and characterize signal pathways of the mesenchymal stem cell line hMSC-TERT which are being influenced by different mediators of inflammation. The purpose was also to ...
(Master thesis / Masteroppgave, 2006)
T-cellespesifikt adapterprotein (TSAd), kodet av SH2D2A genet, blir uttrykt i aktiverte T-celler, NK-celler og i endotelceller. TSAd består hovedsakelig av et SH2-domene og et prolinrikt område og inneholder 10 tyrosiner ...
(Master thesis / Masteroppgave, 2010)
Malignant peripheral nerve sheath tumour (MPNST) is a rare and highly aggressive malignancy with high frequency of both local recurrence and distant metastasis. About half of all cases arise in individuals with the hereditary ...
(Master thesis / Masteroppgave, 2012)
Epigenetic gene regulation is crucial in developmental processes, controlling which genes that are expressed at what times and in what tissues. Posttranslational modifications on histone tail residues yield various outcomes ...
(Master thesis / Masteroppgave, 2008)
SAMMENDRAG
Det går et fint skille mellom medfødt og ervervet immunitet og de to systemene samarbeider på mange områder. Anafylatoksinene C3a og C5a er viktige effektormolekyler som produseres av det medfødte immunforsvaret. ...
Osteogenic differentiation of mesenchymal stem cells : Identification of potential regulators Restricted Access
(Master thesis / Masteroppgave, 2011)
Osteogenic differentiation of mesenchymal stem cells (MSC) is a tightly regulated process, inducing large changes in cell phenotype and gene expression. Characterization of these expressional changes may be important in ...
(Master thesis / Masteroppgave, 2006)
The elongation step of transcription is now recognized as a critical target for transcription regulation. An increasing number of elongation factors have been identified, and the regulatory mechanism of elongation seems ...
(Master thesis / Masteroppgave, 2011)
(Master thesis / Masteroppgave, 2010)
Thioredoxin (Trx) is a small ubiquitous protein containing two conserved cysteines that can reversibely form a redox-active disulfide bond, belonging to the Trx superfamily. Ribonucleotide reductase (RNR) was the first ...
Characterization of the human AlkB homologue 8 (hABH8) Restricted Access
(Master thesis / Masteroppgave, 2008)
The human genome encodes 8 homologues of the E.coli protein AlkB, hABH1-8. AlkB, hABH2, and hABH3 repair DNA and RNA by oxidative demetylation in the presence of Fe2+ and 2-oxoglutarate (2OG). The functions of the remaining ...
(Master thesis / Masteroppgave, 2011)
Abstract
The gram negative obligate human bacterium N. gonorrhoeae possesses a general O-linked glycosylation system with several target proteins. So far twelve glycoproteins have been identified. In all cases where the ...
(Master thesis / Masteroppgave, 2010)
Ovarian carcinoma (OC), primary peritoneal carcinoma (PPC) and malignant mesothelioma (MM) are all highly aggressive tumors that share common morphological features in addition to being histogenetically related. It is of ...
Cell context-dependent differences in interaction with Shiga toxin Restricted Access
(Master thesis / Masteroppgave, 2011)
Cells that grow in a restricted area will eventually become confluent. At that point normal cells will stop dividing, while cancer cells, with their invasive properties, will continue dividing. It has been known for quite ...
Spinal LTP is attenuated by the FAAH enzyme inhibitor URB597 Restricted Access
(Master thesis / Masteroppgave, 2010)
Fatty-acid amide hydrolase (FAAH) is an enzyme that metabolizes several endocannabinoids and fatty acid amides. A functional variant of the gene encoding FAAH, which reduces the enzymatic activity, has been associated with ...
Intracellulær trafikkering av hNCU-G1 i HeLa celler Restricted Access
(Master thesis / Masteroppgave, 2011)
Eskild sin gruppe har klonet hNCU-G1 som viser seg å være et protein med en mulig dobbeltfunksjon. Proteinet ble vist til å være lokalisert i kjernen hvor det kan fungere som en transkripsjonsfaktor og kjernereseptor ...
(Master thesis / Masteroppgave, 2006)
ABSTRACT
Cell-to-cell communication is a vital characteristic of multicellular organisms, making it possible for cells to coordinate their physiological behaviour. Small peptides may act as signalling molecules that ...
(Master thesis / Masteroppgave, 2009)
MicroRNAs (miRNAs) are a relatively newly discovered class of small endogenous non coding RNA molecules with important roles in cell function and cancer development. Mature miRNAs bind to complementary sequences of transcripts ...
(Master thesis / Masteroppgave, 2006)
In this study we have established a method for screening a collection of strains, from the Bacillus cereus group of bacteria, for biofilm formation, including soil isolates, strains from culture collections, reference ...
Distribution and Diversification Processes in cryptomonads, protalveolates and Telonemia investigated by Environmental Sequencing and Phylogenetic Analyses Restricted Access
(Master thesis / Masteroppgave, 2008)
There is a current debate on microbial diversity between the defenders of the cosmopolitan hypothesis, arguing for high gene flow and low diversity, and the defenders of the endemism hypothesis, conversely arguing for ...
(Master thesis / Masteroppgave, 2009)
Identification of novel epigenetic biomarkers in colorectal cancer Restricted Access
(Master thesis / Masteroppgave, 2008)
Colorectal cancer is a common malignancy that develops over a long period of time. Most cases are sporadic, while a small percentage is hereditary, such as hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome). ...
(Master thesis / Masteroppgave, 2011)
Chlamydomonas reinhardtii is a widely used model organism to study chloroplast gene expression and photosynthetic processes. In this project we worked to identify a novel trans-acting factor that is thought to contribute ...
Ligand-receptor matchmaking: The IDA-HAE/HSL2 signaling system and the IDL and HSL relatives Restricted Access
(Master thesis / Masteroppgave, 2009)
Until recently, most intercellular communication in plants has been explained by the signaling and perception of non-peptide plant hormones. It is, however, becoming increasingly clear that plant cell communication also ...
(Master thesis / Masteroppgave, 2006)
Obesity has reached epidemic proportions in western industrialized countries and can be linked to a number of health risks such as hypertension, type 2 diabetes, coronary heart disease, and certain types of cancer. Obesity ...
(Master thesis / Masteroppgave, 2011)
Phage display has been instrumental in discovery of novel binding peptides and folded domains for the past two decades, arguably with most success in the field of drug discovery. Despite being a mature and dominating ...
(Master thesis / Masteroppgave, 2012)
Previous studies show that the endogenous opioid system has an important role in the pain control system. In recent years, it has also been suggested that epigenetic modifications, such as acetylations, may affect pain ...
(Master thesis / Masteroppgave, 2008)
Abstract
Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system
(CNS), and is inactivated by cellular uptake, mostly catalyzed by glutamate (excitatory amino
acid) transporter subtype ...
(Master thesis / Masteroppgave, 2005)
Small peptides can act as signaling molecules that coordinate development, growth and differentiation. In interaction with a receptor the ligand can trigger downstream pathways which induce cellular responses or regulation ...
(Master thesis / Masteroppgave, 2009)
Our group has shown that ultraviolet (UV) irradiation of fission yeast cells in G1 phase induces a delayed entry into S phase. More recently, we found that the cell cycle delay is accompanied by a general depression of ...
(Master thesis / Masteroppgave, 2006)
Sequence-specific double-stranded small interfering RNAs (siRNAs) may effectively silence gene expression via a mechanism called RNA interference (RNAi). The focus of this study was mainly identification of active siRNA ...
Identifisering av interaksjonspartnere til den SUMO-spesifikke proteasen SENP1, ansvarlig for økt genaktivering gjennom deSUMOylering Restricted Access
(Master thesis / Masteroppgave, 2012)
(Master thesis / Masteroppgave, 2006)
SUMMARY
Blood coagulation may lead to venous thromboembolism (VTE). Tissue factor pathway inhibitor (TFPI) is an important inhibitor of blood coagulation, however, the clinical significance or frequency of TFPI deficiency ...
(Master thesis / Masteroppgave, 2005)
Bakgrunn: c-Myb er en sentral regulatorisk transkripsjonsfaktor i hematopoietiske celler og regulerer mange målgener som er involvert i proliferasjon, differensiering og apoptose. For å kunne forklare c-Mybs biologi er det ...
(Master thesis / Hovedoppgave, 2005)
DNA methylation plays an important role in regulating plant development and is associated with the silencing of gene expression. Earlier studies of mammalian and vertebrate cells have shown that there are several ...
(Master thesis / Masteroppgave, 2006)
Radiation is a common treatment of cancer. It can be used either as the primary therapy or as an adjuvant treatment. The objective of radiation therapy is to kill the cancer cells, while minimizing the damage on normal ...
(Master thesis / Masteroppgave, 2007)
Sammendrag
hNCU-G1 ble først identifisert som et protein som interagerte med FP1 i hCRBP-promoteren. Videre studier viste at hNCU-G1 var i stand til å fungere som transkripsjonsfaktor fra denne promoteren. Strukturelle ...
(Master thesis / Masteroppgave, 2011)
(Master thesis / Masteroppgave, 2011)
(Master thesis / Masteroppgave, 2010)
Mental retardation occurs in 2-3% of newborns in the population and can be inherited from the parents, caused by environmental influences or de novo mutations. Microscopically visible chromosome aberrations, such as trisomy ...
(Master thesis / Masteroppgave, 2010)
Legionella er en vannlevende bakterieslekt som er alminnelig i norske innsjøer. Til tross for dette er det vist at Legionella stiller strenge krav til næring når den dyrkes i laboratoriet, og optimal vekst oppnås ved omkring ...
Autofage organeller i rottehepatocytter : En studie av LC3-positive organeller etter separering med isotone tetthetsgradienter Restricted Access
(Master thesis / Masteroppgave, 2009)
Autofagi er en intracellulær prosess eukaryote celler benytter til å bryte ned sitt eget cytoplasma ved langvarig sult eller proteinmangel, til negativ regulering av massevekst, og til spesifikk nedbrytning av ødelagte ...
(Master thesis / Masteroppgave, 2007)
Colorectal cancer is one of the most common cancer types, and a leading cause of cancer-related deaths. Cases can be divided into two main molecular phenotypes: those with chromosomal instability (CIN) and those with ...
(Master thesis / Masteroppgave, 2011)
Syndecans (Syns) are transmembrane heparan sulfate proteoglycans (HSPGs) and comprise a family of four members, Syn 1-4. Syns have important roles as cell surface receptors involved in cell-cell and/or cell-matrix interactions. ...
(Master thesis / Masteroppgave, 2007)
Amplification of several regions of chromosome 8q is frequently detected in breast tumors, and several genes located on this chromosome arm show increased expression in the tumors. One of these genes encodes ã-glutamyl ...
(Master thesis / Masteroppgave, 2007)
The E. coli AlkB protein reverses methylation damage from DNA and RNA by oxidative demethylation, a reaction dependent on Fe(II) and 2-oxoglutarate. Based on sequence similarity, eight human AlkB homologues, denoted hABH1-8, ...
(Master thesis / Masteroppgave, 2007)
Hematopoiesis is the process by which the hematopoietic stem cells differentiate into a variety of specialized cells (mature blood cells). The development of the definitive hematopoietic cell lineages is regulated by a ...
(Master thesis / Masteroppgave, 2007)
Abstracts
1. Production of soluble peptide-MHC class II-Ig fusion proteins
The aim of the study is to construct soluble variants of the murine MHC class II molecule I-Ed in complex with two tumor-specific peptides. ...
(Master thesis / Masteroppgave, 2007)
Abstract.
The c-Myb transcription factor plays a central role in regulation of growth, differentiation and survival of hematopoietic cells. Despite being studied for many years, the understanding of how c-Myb functions ...
(Master thesis / Masteroppgave, 2006)
37 kDa/67 kDa laminin reseptor (LR) er et protein som antas å fungere som en reseptor for prionproteinet, og kan være en mulig kofaktor i omgjøringen av det cellulære prionproteinet, PrPc, til en infeksiøs form, PrPsc, som ...
(Master thesis / Masteroppgave, 2009)
Eskilds gruppe har vist at hNCU-G1 kan fungere som en ligandavhengig koaktivator for kjernereseptorer in vitro. Denne masteroppgaven bruker fluorescenskonfokalmikroskopi til videre å undersøke interaksjonen mellom hNCU-G1 ...
(Master thesis / Masteroppgave, 2008)
The prion protein has been implicated in a number of neurodegenerative diseases of the transmissible spongiform encephalopathy (TSE) type. During disease development, the cellular prion protein (PrPC) undergoes a conformational ...
(Master thesis / Masteroppgave, 2007)
Most vertebrates depend on an uninterrupted supply of oxygen to maintain the energy production. Some species, like the crucian carp (Carassius carassius) can survive hypoxia for an extended period. This fish is an expert ...
Cancer immunosurveillance mediated by CD4+ T cells - focus on dendritic cells and interleukin-1 secretion Restricted Access
(Master thesis / Masteroppgave, 2011)
Tumor-specific CD4+ T cells coordinate the adaptive immune response against cancer. Dendritic cells (DCs) are professional antigen presenting cells that are believed to be important for the initial activation of naïve ...
(Master thesis / Hovedoppgave, 2005)
ABSTRACT rbcL is a constitutively expressed gene in the Chlamydomonas chloroplast. The 5 untranslated region (5 UTR) is predicted to form an RNA secondary structure that might function in RNA stabilization. Earlier studies ...
(Master thesis / Masteroppgave, 2007)
A central question in biology is how cells in multi-cellular organisms communicate. During the development of the organisms, each single cell needs to know their exact position and function, and cell-cell signaling is ...
Molecular and genetic analysis of the MADS-box Type I transcription factors AGAMOUS-LIKE 28 and AGAMOUS-LIKE 36 Restricted Access
(Master thesis / Masteroppgave, 2011)
Abstract
Seed development requires a coordinated interplay between different transcriptional programs in the embryo, the endosperm and the maternally derived seed coat. In angiosperms, the embryo and the endosperm are ...
Characterization and Gene Targeting of the Mammalian AlkB homologue 7 Restricted Access
(Master thesis / Masteroppgave, 2008)
Mammalian AlkB homologues (ABH) contain a 2-oxoglutarate and iron dependent dioxygenase domain, placing these proteins in the 2OG/Fe2+ dependent dioxygenase superfamily. The mammalian ABH2 and ABH3 proteins are oxidative ...
(Master thesis / Masteroppgave, 2011)
Gene therapy strategies have been intensively studied for over 20 years. However, there are yet no gene therapy protocols in conventional use. In this project, a gene delivery protocol was optimized for the transient ...
(Master thesis / Masteroppgave, 2011)
Testicular germ cell tumours are the most frequent type of cancer in young adult Caucasian males. Yet, it is one of the neoplastic diseases with the best prognosis and outcome, making it an ideal model for curative disease. ...
(Master thesis / Masteroppgave, 2009)
In mammals, adult neurogenesis is a restricted phenomenon, taking place in only two distinct areas of the brain, the subventricular zones and the hippocampus. The rate of adult neurogenesis can be regulated through a ...
(Master thesis / Masteroppgave, 2011)
Vitamin D har en potensiell anti-angiogenetisk effekt ved binding av 1,25 dihydroksyvitmin D3 til VDR (vitamin D reseptoren). VDR er en ligand-aktivert transkripsjonsfaktor som binder til VDRE (vitamin D responselementer) ...
(Master thesis / Masteroppgave, 2008)
Post-translational modifications of histones play an important role in regulation of gene transcription. The most well studied histone modification is acetylation that is regulated by the enzymatic activities of histone ...
FcRn expression, ligands binding properties and its regulation in human immune cells and hepatocytes
(Master thesis / Masteroppgave, 2007)
ABSTRACT
Expression and diverse functions of MHC class I related neonatal Fc receptor in different tissues is continually reported. To contribute to the understanding of how the receptor functions according to cell type, ...
A comparative analysis of Ii and MHC II expression during maturation of human monocyte derived dendritic cells Restricted Access
(Master thesis / Masteroppgave, 2007)
The classical MHC II genes in humans, consist of the HLA-DR, HLA-DP and HLA-DQ allotypes, with multiple alleles of each [1]. Their gene products function to present peptides derived from internalized protein antigen to the ...
(Master thesis / Masteroppgave, 2010)
Six transmembrane protein of prostate 2 (STAMP2) is a six transmembrane domain protein in the STAMP/STEAP family. It is primarily found in the prostate, visceral adipose tissue, and bone marrow, and is overexpressed in ...
(Master thesis / Masteroppgave, 2007)
hNCU-G1 ble for første gang identifisert som transkripsjonsfaktor for humant CRBP1. Det baserte seg på EMSA forsøk der man så at det interagerte med FP1 (+66, +99) element i denne promotoren.
hNCU-G1 har fire LXXLL motiver ...
(Master thesis / Masteroppgave, 2012)
Mesenchymal stem cells (MSCs) derived from adipose tissue are multipotent stem cells able to give rise into multiple cell types, not only of the mesodermal lineage, but also of the neuroectodermal lineage. In this study, ...
(Master thesis / Masteroppgave, 2007)
The gene rbcL in the Chlamydomonas chloroplast codes for a mRNA of about 1.6 kb including a 5`UnTranslated Region (5`UTR) of 92 bp.The beginning of the 5`UTR has two stem-loops as part of its secondary structure. A ...
New insights into the regulation of the tumor suppressor proteins PTEN and Connexin 43 by post-translational modifications Restricted Access
(Master thesis / Masteroppgave, 2012)
(Master thesis / Masteroppgave, 2008)
Prionsykdommer er en gruppe nevrodegenerative, dødelige sykdommer som
forekommer hos både dyr og mennesker, og forårsakes av en
konformasjonsendring i det endogene prionproteinet (PrP). I normal hjerne og i flere
andre ...
(Master thesis / Masteroppgave, 2007)
Unique to the lifecycle of plant is the existence of a multicellular haploid gametophyte generation. Elucidation of the genetic makeup of gametophyte development and function is important for several reasons. This phase ...