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(Master thesis / Masteroppgave, 2005)
Prostate cancer (PCa) and obesity are currently two of the most prevalent health problems in the western world. Some epidemiological studies suggest a connection between PCa and fat intake and obesity. In addition, androgens, ...
(Master thesis / Masteroppgave, 2007)
Identifikasjonen av proteinet hNCU-G1 er basert på interaksjonen med hCRBP1-promoterens FP1-element (+66-+99), som ble gjort ved EMSA-studier. Videre studier avslørte at hNCU-G1 kunne fungere som en transkripsjonsfaktor ...
(Master thesis / Masteroppgave, 2005)
Androgen ablation during the initial stages of prostate cancer causes regression of the tumor due to an increase in apoptosis and reduced cellular proliferation. However, some prostate cancer cells survive in the androgen ...
(Master thesis / Masteroppgave, 2011)
Genetisk og funksjonell studie av glykosyltransferase PglA i Neisseria gonorrhoeae og Neisseria lactamica Begrenset tilgang
(Master thesis / Masteroppgave, 2010)
Neisseria er en gruppe gram-negative bakterier som består av både patogene og ikke-patogene arter. Patogene Neisseria fører til store helseproblemer på verdensbasis; Neisseria meningitidis kan forårsake meningokokksykdom, ...
(Master thesis / Masteroppgave, 2009)
Malignant melanoma is a very metastatic and therapy resistant disease, with few therapeutic options in advanced stages. An abnormal apoptosis pathway is considered to contribute substantially to the resistance observed in ...
(Master thesis / Masteroppgave, 2006)
It has previously been found that the sequence and conformation of a 10-nucleotide element in the 5´untranslated region (5´UTR) of rbcL mRNA are important for transcript stability. In this study two variants of a 20-nucleotide ...
PTM-crosstalk in c-Myb : Analysis of interdependence between posttranslational modifications in the negative regulatory domain of the oncoprotein c-Myb. Begrenset tilgang
(Master thesis / Masteroppgave, 2009)
Heterolog ekspresjon av immunitetsproteinet til to-peptidbakteriosinet lactococcin G Begrenset tilgang
(Master thesis / Masteroppgave, 2009)
Bakteriosiner er ribosomalt syntetiserte, antimikrobielle peptider som produseres av en rekke bakteriearter. Lactococcin G er et bakteriosin som består av to peptider, kalt α og β, og produseres av melkesyrebakterien ...
(Master thesis / Masteroppgave, 2008)
Epitelcellelinjen ”Madin-Darby canine kidney (MDCK)” er en velstudert polarisert cellelinje som danner tette cellelag med separate apikale og basolaterale membrandoméner. Proteoglykaner sorteres til både den apikale og den ...
(Master thesis / Masteroppgave, 2008)
Crucian carp (Carassius carassius) avoids lactic acidosis during prolonged periods of anoxia by producing ethanol as the main anaerobic end-product. Apparently, this is made possible by adaptations in the pyruvate dehydrogenase ...
(Master thesis / Masteroppgave, 2009)
High levels of oxidative stress are a common aspect of most neurodegenerative disorders. Oxidative stress in the brain causes DNA lesions that are mainly repaired by the base excision repair (BER) pathway. The BER pathway ...
Targeted delivery of resurfaced gp120 to antigen-presenting cells, a novel vaccine concept in HIV vaccine development Begrenset tilgang
(Master thesis / Masteroppgave, 2011)
DNA vaccines have the ability to induce humoral and cellular immune responses but their efficiency needs further improvement. One strategy is to target the antigen to surface receptors on antigen-presenting cells (APCs), ...
DAXX-dependent recruitment of the histone variant H3.3 to PML bodies prior to chromatin deposition Begrenset tilgang
(Master thesis / Masteroppgave, 2012)
The genome is organized into chromatin domains which can be distinguished by enrichment in post-translational modifications of histones and histone variants. Since the histone code has been discovered, little is known about ...
(Master thesis / Masteroppgave, 2011)
Epitelcellelinjen ”Madin-Darby canine kidney” (MDCK) er en velstudert polarisert cellelinje som danner tette cellelag med separate apikale og basolaterale membrandomener, som ved hjelp av polarisert transport av nysyntetiserte ...
Functional Analysis of Kallikrein 4 in LNCaP cells Begrenset tilgang
(Master thesis / Masteroppgave, 2009)
Prostate cancer is one of the most frequently diagnosed cancers and second highest cause of death in patients who suffer from cancer in western countries. Much effort has been carried out to understand the molecular ...
Functional characterization of a novel human methyltransferase and the generation of corresponding knockout human cell lines Begrenset tilgang
(Master thesis / Masteroppgave, 2010)
This study investigates the function of a novel human protein, which, based on secondary structure prediction, belongs to class I of SAM-dependent methyltransferases (MTases). No specific functions or substrates have yet ...
Targeting Epidermal Growth Factor Receptor 2 in Carcinogenesis Begrenset tilgang
(Master thesis / Masteroppgave, 2009)
Nearly all human tissues express epidermal growth factor receptors(ErbBs)embedded in the plasma membrane. Four homologous ErbB proteins exert a pivotal function of transmitting proliferative signals by binding their cognate ...
(Master thesis / Masteroppgave, 2007)
Human bone marrow multipotent mesenchymal stromal cells (hBM-MSC) represent an appealing source of adult stem cells for cell therapy and tissue engineering. Since hBM-MSC are present at low frequency in the bone marrow, ...
(Master thesis / Masteroppgave, 2012)
At the moment, one-third of the world’s population is estimated to be infected with Mycobacterium tuberculosis (M.tb), the causative agent of tuberculosis (TB) in humans. Our treatment strategies have been greatly challenged ...
Human Endonuclease V - Cloning, Expression, Purification and Biochemical Characterization Begrenset tilgang
(Master thesis / Masteroppgave, 2011)
Multiple DNA damaging agents cause deaminations of the bases of DNA. If not repaired, these can lead to mutations, which in turn can result in dangerous diseases. Endonuclease V (EndoV) is a highly conserved gene from ...
(Master thesis / Masteroppgave, 2008)
The crucian carp (Carassius carassius) inhabits lakes and ponds in Northern Europe, where it is able to survive anoxia that often occurs for months during the long winter. Several physiological adaptations, including the ...
(Master thesis / Masteroppgave, 2011)
Gb3 (Gal α1-4, Gal β1-4, Glc β1-1, Ceramide) is a neutral glycosphingolipid specifically expressed in several human tissues, and is recognised as a receptor for Shiga toxins. Gb3 has been demonstrated to be upregulated in ...
Towards the development of nanobead vaccines against salmon pathogens: : establishment of cold-water fish infection models Begrenset tilgang
(Master thesis / Masteroppgave, 2011)
As the fish farming industry is growing all over the world, economic losses caused by diseases are also increasing. In Norway one fifth of the farmed fish are lost due to viral diseases; there is no treatment for viral ...
(Master thesis / Masteroppgave, 2005)
ABSTRACT
The aim of this thesis was to investigate the in vitro physiological and genetic responses of Bacillus cereus ATCC 14579 to bile, bile salts and mucin, substances which would be encountered in the gastrointestinal ...
(Master thesis / Masteroppgave, 2008)
Animals store most excess energy as fat in specialized cells called adipocytes which form the major part of adipose tissue. Since obesity, which has reached epidemic proportions in the last decades, is the result of excess ...
Osteogenic differentiation of mesenchymal stem cells : Identification of potential regulators Begrenset tilgang
(Master thesis / Masteroppgave, 2011)
Osteogenic differentiation of mesenchymal stem cells (MSC) is a tightly regulated process, inducing large changes in cell phenotype and gene expression. Characterization of these expressional changes may be important in ...
Optimization of a cell free protein synthesis system for expression of Lactococcin A immunity protein Begrenset tilgang
(Master thesis / Masteroppgave, 2012)
Design of an inducible system to control SUMOylation of the transcription factor c-Myb in vivo Begrenset tilgang
(Master thesis / Masteroppgave, 2010)
The transcription factor c-Myb is an important regulator involved in proliferation, differentiation, and apoptosis of hematopoietic cells. Its activity is regulated through interactions with co-repressors and co-activators. ...
(Master thesis / Masteroppgave, 2005)
Abstract
The intention of this study was to identify and characterize signal pathways of the mesenchymal stem cell line hMSC-TERT which are being influenced by different mediators of inflammation. The purpose was also to ...
(Master thesis / Masteroppgave, 2006)
T-cellespesifikt adapterprotein (TSAd), kodet av SH2D2A genet, blir uttrykt i aktiverte T-celler, NK-celler og i endotelceller. TSAd består hovedsakelig av et SH2-domene og et prolinrikt område og inneholder 10 tyrosiner ...
(Master thesis / Masteroppgave, 2010)
Malignant peripheral nerve sheath tumour (MPNST) is a rare and highly aggressive malignancy with high frequency of both local recurrence and distant metastasis. About half of all cases arise in individuals with the hereditary ...
(Master thesis / Masteroppgave, 2012)
Epigenetic gene regulation is crucial in developmental processes, controlling which genes that are expressed at what times and in what tissues. Posttranslational modifications on histone tail residues yield various outcomes ...
(Master thesis / Masteroppgave, 2008)
SAMMENDRAG
Det går et fint skille mellom medfødt og ervervet immunitet og de to systemene samarbeider på mange områder. Anafylatoksinene C3a og C5a er viktige effektormolekyler som produseres av det medfødte immunforsvaret. ...
(Master thesis / Masteroppgave, 2006)
The elongation step of transcription is now recognized as a critical target for transcription regulation. An increasing number of elongation factors have been identified, and the regulatory mechanism of elongation seems ...
(Master thesis / Masteroppgave, 2011)
(Master thesis / Masteroppgave, 2010)
Thioredoxin (Trx) is a small ubiquitous protein containing two conserved cysteines that can reversibely form a redox-active disulfide bond, belonging to the Trx superfamily. Ribonucleotide reductase (RNR) was the first ...
Characterization of the human AlkB homologue 8 (hABH8) Begrenset tilgang
(Master thesis / Masteroppgave, 2008)
The human genome encodes 8 homologues of the E.coli protein AlkB, hABH1-8. AlkB, hABH2, and hABH3 repair DNA and RNA by oxidative demetylation in the presence of Fe2+ and 2-oxoglutarate (2OG). The functions of the remaining ...
(Master thesis / Masteroppgave, 2011)
Abstract
The gram negative obligate human bacterium N. gonorrhoeae possesses a general O-linked glycosylation system with several target proteins. So far twelve glycoproteins have been identified. In all cases where the ...
(Master thesis / Masteroppgave, 2010)
Ovarian carcinoma (OC), primary peritoneal carcinoma (PPC) and malignant mesothelioma (MM) are all highly aggressive tumors that share common morphological features in addition to being histogenetically related. It is of ...
Cell context-dependent differences in interaction with Shiga toxin Begrenset tilgang
(Master thesis / Masteroppgave, 2011)
Cells that grow in a restricted area will eventually become confluent. At that point normal cells will stop dividing, while cancer cells, with their invasive properties, will continue dividing. It has been known for quite ...
(Master thesis / Masteroppgave, 2006)
ABSTRACT
Cell-to-cell communication is a vital characteristic of multicellular organisms, making it possible for cells to coordinate their physiological behaviour. Small peptides may act as signalling molecules that ...
Spinal LTP is attenuated by the FAAH enzyme inhibitor URB597 Begrenset tilgang
(Master thesis / Masteroppgave, 2010)
Fatty-acid amide hydrolase (FAAH) is an enzyme that metabolizes several endocannabinoids and fatty acid amides. A functional variant of the gene encoding FAAH, which reduces the enzymatic activity, has been associated with ...
Intracellulær trafikkering av hNCU-G1 i HeLa celler Begrenset tilgang
(Master thesis / Masteroppgave, 2011)
Eskild sin gruppe har klonet hNCU-G1 som viser seg å være et protein med en mulig dobbeltfunksjon. Proteinet ble vist til å være lokalisert i kjernen hvor det kan fungere som en transkripsjonsfaktor og kjernereseptor ...
(Master thesis / Masteroppgave, 2009)
MicroRNAs (miRNAs) are a relatively newly discovered class of small endogenous non coding RNA molecules with important roles in cell function and cancer development. Mature miRNAs bind to complementary sequences of transcripts ...
(Master thesis / Masteroppgave, 2006)
In this study we have established a method for screening a collection of strains, from the Bacillus cereus group of bacteria, for biofilm formation, including soil isolates, strains from culture collections, reference ...
Distribution and Diversification Processes in cryptomonads, protalveolates and Telonemia investigated by Environmental Sequencing and Phylogenetic Analyses Begrenset tilgang
(Master thesis / Masteroppgave, 2008)
There is a current debate on microbial diversity between the defenders of the cosmopolitan hypothesis, arguing for high gene flow and low diversity, and the defenders of the endemism hypothesis, conversely arguing for ...
(Master thesis / Masteroppgave, 2009)
Identification of novel epigenetic biomarkers in colorectal cancer Begrenset tilgang
(Master thesis / Masteroppgave, 2008)
Colorectal cancer is a common malignancy that develops over a long period of time. Most cases are sporadic, while a small percentage is hereditary, such as hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome). ...
(Master thesis / Masteroppgave, 2011)
Chlamydomonas reinhardtii is a widely used model organism to study chloroplast gene expression and photosynthetic processes. In this project we worked to identify a novel trans-acting factor that is thought to contribute ...
Ligand-receptor matchmaking: The IDA-HAE/HSL2 signaling system and the IDL and HSL relatives Begrenset tilgang
(Master thesis / Masteroppgave, 2009)
Until recently, most intercellular communication in plants has been explained by the signaling and perception of non-peptide plant hormones. It is, however, becoming increasingly clear that plant cell communication also ...
(Master thesis / Masteroppgave, 2006)
Obesity has reached epidemic proportions in western industrialized countries and can be linked to a number of health risks such as hypertension, type 2 diabetes, coronary heart disease, and certain types of cancer. Obesity ...
(Master thesis / Masteroppgave, 2011)
Phage display has been instrumental in discovery of novel binding peptides and folded domains for the past two decades, arguably with most success in the field of drug discovery. Despite being a mature and dominating ...
(Master thesis / Masteroppgave, 2012)
Previous studies show that the endogenous opioid system has an important role in the pain control system. In recent years, it has also been suggested that epigenetic modifications, such as acetylations, may affect pain ...
(Master thesis / Masteroppgave, 2008)
Abstract
Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system
(CNS), and is inactivated by cellular uptake, mostly catalyzed by glutamate (excitatory amino
acid) transporter subtype ...
(Master thesis / Masteroppgave, 2005)
Small peptides can act as signaling molecules that coordinate development, growth and differentiation. In interaction with a receptor the ligand can trigger downstream pathways which induce cellular responses or regulation ...
(Master thesis / Masteroppgave, 2009)
Our group has shown that ultraviolet (UV) irradiation of fission yeast cells in G1 phase induces a delayed entry into S phase. More recently, we found that the cell cycle delay is accompanied by a general depression of ...
(Master thesis / Masteroppgave, 2006)
Sequence-specific double-stranded small interfering RNAs (siRNAs) may effectively silence gene expression via a mechanism called RNA interference (RNAi). The focus of this study was mainly identification of active siRNA ...
Identifisering av interaksjonspartnere til den SUMO-spesifikke proteasen SENP1, ansvarlig for økt genaktivering gjennom deSUMOylering Begrenset tilgang
(Master thesis / Masteroppgave, 2012)
(Master thesis / Masteroppgave, 2009)
(Master thesis / Masteroppgave, 2012)
Previous studies indicate that central sensitization may be an underlying mechanism of hyperalgesia and development of persistent pain. However, some individuals may have a higher risk of long lasting pain than others, ...
(Master thesis / Masteroppgave, 2007)
Prostate cancer is the most common non-skin cancer and the third leading cause of cancer death in men in developed countries. No effective cure has yet been found to treat the hormone refractory state of PCa. In addition ...
Structure of Thermotoga maritima endonuclease V binding to DNA Begrenset tilgang
(Master thesis / Prosjektoppgave, 2012)
Abstract
Endonuclease V (EndoV) is highly conserved from prokaryotes to eukaryotes. Endonuclease V in E. coli functions in repair of DNA damages caused by deamination of adenine and guanine in particular. E. coli EndoV ...
Iron acquisition of Legionella bozemanii and possible effects of cyanobacterial microcystin Begrenset tilgang
(Master thesis / Masteroppgave, 2010)
(Master thesis / Masteroppgave, 2007)
In the 5`UTR of transcripts of the Chlamydomonas chloroplast gene rbcL secondary structures in the shape of two stem loops, one large and one small, have been identified. The large stem loop has been found to mediate folding ...
An unbalanced (X;22) translocation in a neurodevelopmentally delayed girl : Does the X-inactivation spread to chr22? Begrenset tilgang
(Master thesis / Masteroppgave, 2012)
Intellectual disability/mental retardation occur in 2-3% of newborns in the general population. In 80% of the cases, the causes remain elusive. Improved molecular and cytogenetic techniques have enabled the detection of ...
(Master thesis / Masteroppgave, 2008)
SUMMARY
Mesenchymal stem cells (MSCs) have been identified in several adult tissues and have the ability to differentiate into multiple cell types. However, not all MSC types differentiate efficiently into all lineages. ...
(Master thesis / Masteroppgave, 2011)
The invariant chain (Ii) has for many years been known to have important functions in MHC class II antigen presentation. There are four isoforms of Ii in humans: Iip33, Iip35, Iip41 and Iip43. The two shorter isoforms ...
The antinociceptive effect of the FAAH inhibitior URB597 is blocked by the opioid receptor antagonist naloxone Begrenset tilgang
(Master thesis / Masteroppgave, 2011)
Previous studies indicate that inhibition of fatty acid amide hydrolase (FAAH) activity may result in accumulation of endocannabinoids both in the brain and the spinal cord. Furthermore, it has been suggested that the ...
(Master thesis / Masteroppgave, 2012)
Abstract
The concept that messenger RNA (mRNA) degradation in E. coli begins with endonucleolytic cleavage has been challenged by the recent discovery that the conversion of the 5’ terminus from a triphosphate to a ...
Identification of a new interaction partner of the small GTPase Rab7b Begrenset tilgang
(Master thesis / Masteroppgave, 2012)
The small GTPase Rab7b is localized to late endosomes and lysosomes and to the Golgi apparatus, and regulates the intracellular transport from late endosomal compartments to the Golgi. However, not much is known about ...
(Master thesis / Masteroppgave, 2012)
Ectoine is a small molecule that confers salt tolerance to organisms. It is synthesized in bacteria by the gene products of ectA, ectB, and ectC. Ectoine is used in medical, biotechnological, and cosmetic products.
The ...
In vitro ekspresjonssystem for produksjon av bakteriosiner og immunitets proteiner Begrenset tilgang
(Master thesis / Masteroppgave, 2012)
The structures of the immunity proteins for the two-peptide bacteriocins have not been determined, although knowledge of these structures is of great interest as it may reveal at a molecular level how these proteins render ...
(Master thesis / Masteroppgave, 2012)
Colorectal cancer (CRC) is a common type of cancer, and at present the TNM staging system is the only tool in routine clinical use for predicting patient outcome and making treatment decisions. Nuclear expression of the ...
Molecular and genetic analysis of novel genes involved in imprinting in seed development Begrenset tilgang
(Master thesis / Masteroppgave, 2010)
A cluster of genes in both animals and flowering plants are expressed only from one of the two homologous chromosomes, depending upon whether they are maternally or paternally inherited. This phenomenon is called imprinting, ...
(Master thesis / Masteroppgave, 2008)
The gram-negative bacterium Neisseria gonorrhoeae utilizes an O-linked glycosylation system to decorate a selected set of its proteins. So far however, no glycosylation associated phenotypes have been detected. The most ...
(Master thesis / Masteroppgave, 2012)
Paratuberculosis is a chronic enteric disease that affects ruminants. It is caused by Mycobacterium avium subsp. paratuberculosis (MAP) an obligated intracellular acid-fast bacilli that usually infect macrophages in the ...
(Master thesis / Hovedoppgave, 2005)
The female gametophyte of higher plants gives rise to the diploid embryo and the triploid endosperm which develop to produce the mature seed. Seed development is a concerted interplay of the embryo, endosperm and the ...
Functional analysis of STAMP1 and a putative interaction partner in prostate cancer Begrenset tilgang
(Master thesis / Masteroppgave, 2011)
Characterization of novel methyltransferases METTL22 and FAM86A.1 Begrenset tilgang
(Master thesis / Masteroppgave, 2012)
Proteins are subjected to various post-translational modifications (PTMs) that affect their activity, interaction and localization. Methylation is one such PTM that is well known to play a regulatory role in heterochromatin ...
Characterization of proteoglycan expression by B lymphocytes Begrenset tilgang
(Master thesis / Masteroppgave, 2011)
The Role of SNX8 in Retrograde Transport of Shiga Toxin : SNX8 facilitated transport of Shiga toxin is regulated by PKCdelta and p38alfa Begrenset tilgang
(Master thesis / Masteroppgave, 2010)
Sorting nexin 8 (SNX8) belongs to the sorting nexin protein family. Members of this family are known to be involved in endocytosis and endosomal sorting. It was recently reported that SNX8 regulates retrograde transport ...
Temperaturens rolle for vekst og overlevelse av Legionella bozemanii og Legionella pneumophila Begrenset tilgang
(Master thesis / Masteroppgave, 2012)
(Master thesis / Masteroppgave, 2012)
Sensitization of sensory neurons after noxious conditioning may be involved in many chronic pain states, including radiating low back pain and sciatica following disc herniation. Here, we examine such sensitization induced ...
(Master thesis / Masteroppgave, 2011)
In addition to providing morphological support, the actin cytoskeleton is involved in cell motility, endocytosis and intracellular transport. Cytoskeletal interaction with the membrane is an essential part of these processes ...
(Master thesis / Masteroppgave, 2011)
Colorectal cancer is one of the most prevalent causes of cancer deaths worldwide, with an estimated 1500 deaths each year in Norway alone. Early detection of colorectal cancer may significantly reduce this number, and it ...
(Master thesis / Masteroppgave, 2006)
Radiation is a common treatment of cancer. It can be used either as the primary therapy or as an adjuvant treatment. The objective of radiation therapy is to kill the cancer cells, while minimizing the damage on normal ...
(Master thesis / Masteroppgave, 2007)
Sammendrag
hNCU-G1 ble først identifisert som et protein som interagerte med FP1 i hCRBP-promoteren. Videre studier viste at hNCU-G1 var i stand til å fungere som transkripsjonsfaktor fra denne promoteren. Strukturelle ...
(Master thesis / Masteroppgave, 2011)
(Master thesis / Masteroppgave, 2011)
(Master thesis / Masteroppgave, 2010)
Mental retardation occurs in 2-3% of newborns in the population and can be inherited from the parents, caused by environmental influences or de novo mutations. Microscopically visible chromosome aberrations, such as trisomy ...
(Master thesis / Masteroppgave, 2010)
Legionella er en vannlevende bakterieslekt som er alminnelig i norske innsjøer. Til tross for dette er det vist at Legionella stiller strenge krav til næring når den dyrkes i laboratoriet, og optimal vekst oppnås ved omkring ...
Autofage organeller i rottehepatocytter : En studie av LC3-positive organeller etter separering med isotone tetthetsgradienter Begrenset tilgang
(Master thesis / Masteroppgave, 2009)
Autofagi er en intracellulær prosess eukaryote celler benytter til å bryte ned sitt eget cytoplasma ved langvarig sult eller proteinmangel, til negativ regulering av massevekst, og til spesifikk nedbrytning av ødelagte ...
(Master thesis / Masteroppgave, 2007)
Colorectal cancer is one of the most common cancer types, and a leading cause of cancer-related deaths. Cases can be divided into two main molecular phenotypes: those with chromosomal instability (CIN) and those with ...
(Master thesis / Masteroppgave, 2011)
Syndecans (Syns) are transmembrane heparan sulfate proteoglycans (HSPGs) and comprise a family of four members, Syn 1-4. Syns have important roles as cell surface receptors involved in cell-cell and/or cell-matrix interactions. ...
(Master thesis / Masteroppgave, 2007)
Amplification of several regions of chromosome 8q is frequently detected in breast tumors, and several genes located on this chromosome arm show increased expression in the tumors. One of these genes encodes ã-glutamyl ...
(Master thesis / Masteroppgave, 2007)
The E. coli AlkB protein reverses methylation damage from DNA and RNA by oxidative demethylation, a reaction dependent on Fe(II) and 2-oxoglutarate. Based on sequence similarity, eight human AlkB homologues, denoted hABH1-8, ...
(Master thesis / Masteroppgave, 2007)
Hematopoiesis is the process by which the hematopoietic stem cells differentiate into a variety of specialized cells (mature blood cells). The development of the definitive hematopoietic cell lineages is regulated by a ...
(Master thesis / Masteroppgave, 2007)
Abstracts
1. Production of soluble peptide-MHC class II-Ig fusion proteins
The aim of the study is to construct soluble variants of the murine MHC class II molecule I-Ed in complex with two tumor-specific peptides. ...