Browsing Det medisinske fakultet by Title
Now showing items 1-20 of 22101
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(Doctoral thesis / Doktoravhandling, 2022)The thesis aims were to explore 1) genetic underpinnings of apathy in schizophrenia spectrum disorders (SZ) and healthy controls (HC), 2) prevalence of persistent apathy (PA), persistent depression (PD) and associations ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Injecting drug users have a mortality risk between 10 and 20 times higher than the general population, and the persistent high mortality rate in most Western countries, and especially in Norway, is a major public health ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)High-risk neuroblastomas typically display an undifferentiated or poorly differentiated morphology. It is therefore vital to understand molecular mechanisms that block the differentiation process. We identify an important ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Objectives Gout is often not adequately treated, and we aimed to apply urate lowering treatment (ULT) combined with individual information to achieve target serum urate (sUA) in clinical practice, and to identify predictors ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)Studies from several countries suggest that erecting fences on bridges more commonly used for suicide by jumping may be an effective way of reducing the risk of suicide by jumping from these bridges. Distribution of suicides ...
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12-year prediction of mild cognitive impairment aided by Alzheimer's brain signatures at mean age 56 (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Abstract Neuroimaging signatures based on composite scores of cortical thickness and hippocampal volume predict progression from mild cognitive impairment to Alzheimer’s disease. However, little is known about ...
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(Master thesis / Prosjektoppgave, 2008)Background Patients presenting with acute abdominal pain is a diagnostic challenge for the primary care physician. Although a large proportion of the illnesses are innocuous and self limiting, the possibility of encountering ...
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(Doctoral thesis / Doktoravhandling, 2011)The main aim of this thesis was to determine the clinical usefulness of breath tests with 13C-labelled substrates to diagnose small intestinal malabsorption. To this end we studied patients with coeliac disease, one of the ...
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16S Ribosomal RNA gene sequences from cardiac valve tissue convey the diagnosis of culture-negative endocarditisRestricted Access (Master thesis / Prosjektoppgave, 2011)Objectives: Culture-negative endocarditis (CNE) accounts for nearly half of all cases of infectious endocarditis (IE). Prior or concurrent antibiotic treatment at the time of blood cultures taken accounts for 45% - 60% ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Background CD37 is an internalizing B-cell antigen expressed on Non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia cells (CLL). The anti-CD37 monoclonal antibody HH1 was conjugated to the bifunctional chelator ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Patients with non-Hodgkin lymphoma (NHL) who are treated with rituximab may develop resistant disease, often associated with changes in expression of CD20. The next-generation β-particle–emitting radioimmunoconjugate ...
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(Master thesis / Prosjektoppgave, 2007)ABSTRACT In recent years the use of 18F-Fluorodeoxyglucose (FDG) Positron Emission Tomography for the evaluation of head and neck cancers has increased, mainly with the introduction of fused PET/CT imaging. This new imaging ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)The aim of this study was to assess the risk of atherosclerosis in patients with lung cancer compared to patients with extrapulmonary malignancies using 18F-fluorodeoxyglucose-positron emission tomography/computed tomography ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Rheumatoid arthritis (RA) involves chronic inflammation of synovial joints, causing pain, stiffness, and limited mobility. 18F-sodium fluoride (NaF) is a PET tracer whose uptake reflects bone turnover, while 18F-fludeoxyglucose ...
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(Doctoral thesis / Doktoravhandling, 2020)Stroke leads to severe disability and death worldwide. An atherosclerotic plaque causing stenosis of the carotid artery is an important cause of ischemic stroke. Today’s treatment selection is mainly based on the degree ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Background 18F-fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) is used in the clinical management of oncologic and inflammatory pathologies. It may have utility in detecting radiotherapy ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Radiation therapy (RT) is an important component of care for head and neck cancers (HNC). Photon RT vasculitis is a complication of incidental dose delivery to nearby vascular structures. However, optimal methods for early ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Abstract The PET tracer 18F-fluciclovine (Axumin) was recently approved in the United States and Europe for men with suspected prostate cancer recurrence following prior treatment. This article summarizes studies where ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Flutemetamol (18F-Flut) is an [18F]-labelled amyloid PET tracer with increasing availability. The main objectives of this study were to investigate 1) cerebrospinal fluid (CSF) Aβ 1-42 (Aβ42) concentrations associated with ...
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(Doctoral thesis / Doktoravhandling, 2023)Alzheimer´s disease (AD) is a devastating brain disease and the most common cause of dementia. Plaques found in the cortex considered a hallmark of the disease, may be demonstrated 10-20 years before the onset of symptoms. ...