Browsing Det medisinske fakultet by Author "Yadavilli, Sridevi"

Now showing items 1-3 of 3

  • ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma 
    Jackson, Evangeline R.; Duchatel, Ryan J.; Staudt, Dilana E.; Persson, Mika L.; Mannan, Abdul; Yadavilli, Sridevi; Parackal, Sarah; Game, Shaye; Chong, Wai Chin; Jayasekara, W.N. Samantha; Le Grand, Marion; Kearney, Padraic S.; Douglas, Alicia M.; Findlay, Izac J.; Germon, Zacary P.; McEwen, Holly P.; Beitaki, Tyrone S.; Patabendige, Adjanie; Skerrett-Byrne, David A.; Nixon, Brett; Smith, Nathan D.; Day, Bryan; Manoharan, Neevika; Nagabushan, Sumanth; Hansford, Jordan R.; Govender, Dinisha; McCowage, Geoff B.; Firestein, Ron; Howlett, Meegan; Endersby, Raelene; Gottardo, Nicholas G.; Alvaro, Frank; Waszak, Sebastian Martin; Larsen, Martin R.; Colino-Sanguino, Yolanda; Valdes-Mora, Fatima; Rakotomalala, Andria; Meignan, Samuel; Pasquier, Eddy; André, Nicolas; Hulleman, Esther; Eisenstat, David D.; Vitanza, Nicholas A.; Nazarian, Javad; Koschmann, Carl; Mueller, Sabine; Cain, Jason E.; Dun, Matthew D. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Diffuse midline gliomas (DMG), including diffuse intrinsic pontine gliomas (DIPG), are the most lethal of childhood cancers. Palliative radiotherapy is the only established treatment, with median patient survival of 9 to ...
  • Pan-cancer atlas of somatic core and linker histone mutations 
    Bonner, Erin R.; Dawood, Adam; Gordish-Dressman, Heather; Eze, Augustine; Bhattacharya, Surajit; Yadavilli, Sridevi; Mueller, Sabine; Waszak, Sebastian Martin; Nazarian, Javad (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Recent genomic data points to a growing role for somatic mutations altering core histone and linker histone-encoding genes in cancer. However, the prevalence and the clinical and biological implications of histone ...
  • Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker Outcomes from PNOC003 
    Kline, Cassie; Jain, Payal; Kilburn, Lindsay; Bonner, Erin R.; Gupta, Nalin; Crawford, John R.; Banerjee, Anu; Packer, Roger J.; Villanueva-Meyer, Javier; Luks, Tracy; Zhang, Yalan; Kambhampati, Madhuri; Zhang, Jie; Yadavilli, Sridevi; Zhang, Bo; Gaonkar, Krutika S.; Rokita, Jo Lynne; Kraya, Adam; Kuhn, John; Liang, Winnie; Byron, Sara; Berens, Michael; Molinaro, Annette; Prados, Michael; Resnick, Adam; Waszak, Sebastian Martin; Nazarian, Javad; Mueller, Sabine (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract Purpose: PNOC003 is a multicenter precision medicine trial for children and young adults with newly diagnosed diffuse intrinsic pontine glioma (DIPG). ...