Browsing Det medisinske fakultet by Author "Vaclová, Tereza"

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  • Dual targeting of BRAF and mTOR signaling in melanoma cells with pyridinyl imidazole compounds 
    Palušová, Veronika; Renzová, Tereza; Verlande, Amandine; Vaclová, Tereza; Medková, Michaela; Cetlová, Linda; Sedláčková, Miroslava; Hříbková, Hana; Slaninová, Iva; Krutá, Miriama; Rotrekl, Vladimír; Uhlirova, Hana; Křížová, Aneta; Chmelík, Radim; Veselý, Pavel; Krafcikova, Michaela; Trantirek, Lukas; Schink, Kay Oliver; Uldrijan, Stjepan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    BRAF inhibitors can delay the progression of metastatic melanoma, but resistance usually emerges, leading to relapse. Drugs simultaneously targeting two or more pathways essential for cancer growth could slow or prevent ...