Browsing Det medisinske fakultet by Author "Vaage, John T."

Now showing items 1-20 of 24

  • Covid-19-pasienter behandlet med rekonvalesensplasma 
    Nissen-Meyer, Lise Sofie Haug; Macpherson, Magnhild Eide; Skeie, Linda Gail; Hvalryg, Marte; LLOHN, ABID HUSSAIN; Steinsvåg, Tine Torsvik; Fenstad, Mona H.; Tveita, Anders; Kristoffersen, Einar Klæboe; Sundic, Tatjana; Lund-Johansen, Fridtjof; Vaage, John T.; Flesland, Øystein; Dyrhol-Riise, Anne Ma; Holter, Jan Cato; Hervig, Tor Audun; Fevang, Børre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    BAKGRUNN I Norge er behandling med covid-19-rekonvalesensplasma gitt gjennom NORPLASMA-prosjektet. I begynnelsen ble behandlingen tilbudt kritisk syke pasienter etter individuell vurdering, men fra desember 2020 ble ...
  • Degranulation Response in Cytotoxic Rat Lymphocytes Measured with a Novel CD107a Antibody 
    Sudworth, Amanda; Dai, Kezheng; Vaage, John T.; Kveberg, Lise (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Measuring degranulation through CD107a expression has become an advantageous tool for testing the functional capacity of cytotoxic cells. Such functional studies have been hampered in the rat by the lack of a suitable ...
  • Frontline Science: A hyporesponsive subset of rat NK cells negative for Ly49s3 and NKR-P1B are precursors to the functionally mature NKR-P1B+ subset 
    Sudworth, Amanda; Vaage, John T.; Inngjerdingen, Marit; Kveberg, Lise (Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
    Rat NK cells are divided into major subsets expressing either Ly49 receptors or the inhibitory NKR‐P1B receptor in conjunction with NKG2A/C/E receptors. A minor subset of NKp46+ cells lacking expression of both Ly49 receptors ...
  • HLA-DRB3*01:01 exhibits a dose-dependent impact on HPA-1a antibody levels in HPA-1a-immunized women 
    Kjeldsen-Kragh, Jens; Titze, Thomas Larsen; Lie, Benedicte Alexandra; Vaage, John T.; Kjær, Mette (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    HLA-DRB3*01:01 is a predisposing factor for human platelet antigen 1a (HPA-1a) immunization, which is responsible for most cases of fetal and neonatal alloimmune thrombocytopenia. The aim of this study was to investigate ...
  • Humoral and cellular immune responses to two and three doses of SARS-CoV-2 vaccines in rituximab-treated patients with rheumatoid arthritis: a prospective, cohort study 
    Jyssum, Ingrid; Kared, Hassen; Tran, Trung; Tveter, Anne Therese; Provan, Sella Aarrestad; Sexton, Joseph; Jørgensen, Kristin Kaasen; Jahnsen, Jørgen; Kro, Grete Anette Birkeland; Warren, David; Vaage, Eline Benno; Kvien, Tore Kristian; Nissen-Meyer, Lise Sofie Haug; Anderson, Ane Marie; Grødeland, Gunnveig; Haavardsholm, Espen A.; Vaage, John T.; Mjaaland, Siri; Syversen, Silje Watterdal; Lund-Johansen, Fridtjof; Munthe, Ludvig Andre; Goll, Guro Løvik (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
    Background In rituximab-treated patients with rheumatoid arthritis, humoral and cellular immune responses after two or three doses of SARS-CoV-2 vaccines are not well characterised. We aimed to address this knowledge ...
  • Humoral immune response to SARS-CoV-2 vaccination in patients with inflammatory bowel disease on immunosuppressive medication: association to serum drug levels and disease type 
    Jørgensen, Kristin Kaasen; Høivik, Marte Lie; Chopra, Adity; Saltyte Benth, Jurate; Ricanek, Petr; Moum, Bjørn Allan; Jyssum, Ingrid; Bolstad, Nils; Warren, David; Vaage, John T.; Munthe, Ludvig Andre; Lundin, Knut Erik Aslaksen; Anisdahl, Karoline; Syversen, Silje Watterdal; Goll, Guro Løvik; Lund-Johansen, Fridtjof; Medhus, Asle Wilhelm; Jahnsen, Jørgen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Objectives Immune responses following SARS-CoV-2 vaccination in patients with inflammatory bowel disease (IBD) are not well characterized. The aims of this study were to explore the serological response associated with ...
  • Humoral Response After 6 or More Successive Doses of SARS-CoV-2 mRNA Vaccines in Kidney Transplant Recipients-Should We Keep Vaccinating? 
    Åsberg, Anders; Hovd, Markus Herberg; Kjellevold, Stig Arne; Stenehjem, Aud Eldrid; Wien, Tale Norbye; Broch, Lars Ulrik; Reier-Nielsen, Morten; Hatlestad Qvale, Tor; Marti, Hans-Peter; Heldal, Kristian; Bitter, Jan; Hagelsteen Kvien, Elisabeth; Vaage, John T.; Lund-Johansen, Fridtjof; Midtvedt, Karsten (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
  • Humoral vaccine response and breakthrough infections in kidney transplant recipients during the COVID-19 pandemic: a nationwide cohort study 
    Hovd, Markus Herberg; Åsberg, Anders; Munthe, Ludvig Andre; Heldal, Kristian; Reisæter, Anna Varberg; Vaage, John T.; Lund-Johansen, Fridtjof; Midtvedt, Karsten (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background Kidney transplant recipients (KTRs) experienced reduced SARS-CoV-2 vaccine response and were at increased risk of severe COVID-19. It is unknown if level of vaccine induced anti-receptor binding domain IgG ...
  • Hybrid and SARS-CoV-2-vaccine immunity in kidney transplant recipients 
    Kared, Hassen; Alirezaylavasani, Amin; Lund, Katrine Persgård; Chopra, Adity; Tietze, Lisa; de Matos Kasahara, Taissa; Goll, Guro Løvik; Grødeland, Gunnveig; Kaarbø, Mari; Reisæter, Anna Varberg; Hovd, Markus Herberg; Vaage, John T.; Lund-Johansen, Fridtjof; Midtvedt, Karsten; Åsberg, Anders; Munthe, Ludvig Andre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background Kidney transplant recipients (KTR) are at high risk for severe COVID-19 and have demonstrated poor response to vaccination, making it unclear whether successive vaccinations offer immunity and protection. ...
  • Immune responses in Omicron SARS-CoV-2 breakthrough infection in vaccinated adults 
    Kared, Hassen; Wolf, Asia-Sophia Fumika Michaela; Alirezaylavasani, Amin; Ravussin, Anthony; Solum, Guri; Tran, Trung The; Lund-Johansen, Fridtjof; Vaage, John T.; Nissen-Meyer, Lise Sofie Haug; Nygaard, Unni Cecilie; Hungnes, Olav; Robertson, Anna Hayman; Næss, Lisbeth Meyer; Trogstad, Lill; Magnus, Per Minor; Munthe, Ludvig Andre; Mjaaland, Siri (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract The SARS-CoV-2 Omicron variant has more than 15 mutations in the receptor binding domain of the Spike protein enabling increased transmissibility and viral escape from antibodies in vaccinated individuals. It is ...
  • Immune responses to SARS-CoV-2 vaccines in celiac disease 
    Ibsen, Jostein Holen; Chopra, Adity; Vaage, Eline Benno; Vaage, John T.; Lund-Johansen, Fridtjof; Lundin, Knut (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background and aims SARS-CoV-2 infection and development of the disease COVID-19 is a serious threat to our society. Effective vaccines have now entered the market, but most patient populations were not included in the ...
  • Immunogenicity and safety of a three-dose SARS-CoV-2 vaccination strategy in patients with immune-mediated inflammatory diseases on immunosuppressive therapy 
    Syversen, Silje Watterdal; Jyssum, Ingrid; Tveter, Anne Therese; Sexton, Joseph; Christensen, Ingrid Egeland; Tran, Trung; Hammersbøen, Kristin Reine; Mjaaland, Siri; Warren, David; Kvien, Tore Kristian; Chopra, Adity; Kro, Grete Anette Birkeland; Jahnsen, Jørgen; Munthe, Ludvig Andre; Haavardsholm, Espen A.; Grødeland, Gunnveig; Vaage, John T.; Provan, Sella Aarrestad; Jørgensen, Kristin Kaasen; Goll, Guro Løvik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Objectives Humoral vaccine responses to SARS-CoV-2 vaccines are impaired and short lasting in patients with immune-mediated inflammatory diseases (IMID) following two vaccine doses. To protect these vulnerable patients ...
  • Immunogenicity and Safety of Standard and Third-Dose SARS-CoV-2 Vaccination in Patients Receiving Immunosuppressive Therapy 
    Syversen, Silje Watterdal; Jyssum, Ingrid; Tveter, Anne Therese; Tran, Trung; Sexton, Joseph; Provan, Sella Aarrestad; Mjaaland, Siri; Warren, David; Kvien, Tore Kristian; Grødeland, Gunnveig; Nissen-Meyer, Lise Sofie Haug; Ricanek, Petr; Chopra, Adity; Andersson, Ane Marte; Kro, Grete Anette Birkeland; Jahnsen, Jørgen; Munthe, Ludvig Andre; Haavardsholm, Espen A.; Vaage, John T.; Lund-Johansen, Fridtjof; Jørgensen, Kristin Kaasen; Goll, Guro Løvik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Objective Immunogenicity and safety following receipt of the standard SARS–CoV-2 vaccination regimen in patients with immune-mediated inflammatory diseases (IMIDs) are poorly characterized, and data after receipt of the ...
  • Mode of perfusion influences infarct size, coronary flow and stress kinases in the isolated mouse heart 
    Bliksøen, Marte; Rutkovskiy, Arkady; Vaage, John T.; Stensløkken, Kåre-Olav (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    Aim: The isolated, retrogradely perfused heart (modified Langendorff model) is a widely used method in experimental heart research. The presence of an intraventricular balloon is necessary to get functional measurements. ...
  • People who use drugs show no increase in pre-existing T-cell cross-reactivity toward SARS-CoV-2 but develop a normal polyfunctional T-cell response after standard mRNA vaccination 
    Gainullin, Murat; Federico, Lorenzo; Osen, Julie Røkke; Chaban, Viktoriia; Kared, Hassen; Alirezaylavasani, Amin; Lund-Johansen, Fridtjof; Wildendahl, Gull; Jacobsen, Jon-Aksel; Sarwar Anjum, Hina; Stratford, Richard; Tennøe, Simen; Malone, Brandon; Clancy, Trevor; Vaage, John T.; Henriksen, Kathleen; Wüsthoff, Linda Elise; Munthe, Ludvig Andre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    People who use drugs (PWUD) are at a high risk of contracting and developing severe coronavirus disease 2019 (COVID-19) and other infectious diseases due to their lifestyle, comorbidities, and the detrimental effects of ...
  • Prevalence of antibodies against SARS-CoV-2 in the Norwegian population, August 2021 
    Tunheim, Gro; Rø, Gunnar Øyvind Isaksson; Chopra, Adity; Aase, Audun; Kran, Anne-Marte Bakken; Vaage, John T.; Lund-Johansen, Fridtjof; Hungnes, Olav (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background One year into the COVID-19 pandemic, the cumulative number of confirmed COVID-19 cases in Norway was still low. In January 2021, when the Norwegian COVID-19 vaccination campaign started, the national ...
  • Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants 
    Meyer, Saskia; Blaas, Isaac; Bollineni, Ravi Chand; Delic-Sarac, Marina; Tran, Trung; Knetter, Cathrine; Dai, Kezheng; Madssen, Torfinn Støve; Vaage, John T.; Gustavsen, Alice; Yang, Weiwen; Nissen-Meyer, Lise Sofie Haug; Douvlataniotis, Karolos; Laos, Maarja; Nielsen, Morten Milek; Thiede, Bernd; Søraas, Arne Vasli Lund; Lund-Johansen, Fridtjof; Rustad, Even Holth; Olweus, Johanna (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    The emergence of SARS-CoV-2 variants of concern (VOC) is driven by mutations that mediate escape from neutralizing antibodies. There is also evidence that mutations can cause loss of T cell epitopes. However, studies on ...
  • Rituximab-treated patients with lymphoma develop strong CD8 T-cell responses following COVID-19 vaccination 
    Riise, Jon; Meyer, Saskia; Blaas, Isaac; Chopra, Adity; Tran, Trung; Delic-Sarac, Marina; Hestdalen, Malu Lian; Brodin, Ellen Elisabeth; Rustad, Even Holth; Dai, Ke-Zheng; Vaage, John T.; Nissen-Meyer, Lise Sofie Haug; Sund, Fredrik; Wader, Karin Fahl; Bjørnevik, Anne Turid; Meyer, Peter Albert; Nygaard, Gro Owren; König, Marton; Smeland, Sigbjørn; Lund-Johansen, Fridtjof; Olweus, Johanna; Kolstad, Arne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    B-cell depletion induced by anti-cluster of differentiation 20 (CD20) monoclonal antibody (mAb) therapy of patients with lymphoma is expected to impair humoral responses to severe acute respiratory syndrome coronavirus-2 ...
  • Robust spike-specific CD4+ and CD8+ T cell responses in SARS-CoV-2 vaccinated hematopoietic cell transplantation recipients: a prospective, cohort study 
    Federico, Lorenzo; Tvedt, Tor Henrik Anderson; Gainullin, Murat; Osen, Julie Røkke; Chaban, Viktoriia; Lund, Kathrine Persgård; Tietze, Lisa; Tran, Trung; Lund-Johansen, Fridtjof; Kared, Hassen; Lind, Andreas; Vaage, John T.; Stratford, Richard; Tennøe, Simen; Malone, Brandon; Clancy, Trevor; Myhre, Anders Eivind; Gedde-Dahl, Tobias; Munthe, Ludvig Andre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Poor overall survival of hematopoietic stem cell transplantation (HSCT) recipients who developed COVID-19 underlies the importance of SARS-CoV-2 vaccination. Previous studies of vaccine efficacy have reported weak humoral ...
  • Seroprevalence of SARS-CoV-2 and humoral immune responses to COVID-19 mRNA vaccines among people who use drugs - in the light of tailored mitigating strategies 
    Wüsthoff, Linda E. C.; Lund-Johansen, Fridtjof; Henriksen, Kathleen; Wildendahl, Gull; Jacobsen, Jon-Aksel; Gomes, Leni; Anjum, Hina S.; Barlinn, Regine; Kran, Anne-Marte B.; Munthe, Ludvig A.; Vaage, John T. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
    Background During the initial wave of the COVID-19 pandemic, there was a surprisingly low incidence of SARS-CoV-2 among People Who Use Drugs (PWUD) in Oslo, Norway, despite their heightened vulnerability ...