dc.date.accessioned | 2023-02-10T18:14:26Z | |
dc.date.available | 2023-02-10T18:14:26Z | |
dc.date.created | 2022-05-13T11:01:07Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | Eskild, Anne Mørkrid, Lars Mortensen, Siri Beisland Leegaard, Truls Michael . Prevalence of antibodies against SARS-CoV-2 among pregnant women in Norway during the period December 2019 through December 2020. Epidemiology and Infection. 2022, 150:e28, 1-3 | |
dc.identifier.uri | http://hdl.handle.net/10852/99878 | |
dc.description.abstract | We studied severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence among pregnant women in Norway by including all women who were first trimester pregnant (n = 6520), each month from December 2019 through December 2020, in the catchment region of Norway's second-largest hospital. We used sera that had been frozen stored after compulsory testing for syphilis antibodies in antenatal care. The sera were analysed with the Elecsys® Anti-SARS-CoV-2 immunoassay (Roche Diagnostics, Cobas e801). This immunoassay detects IgG/IgM against SARS-CoV-2 nucleocapsid antigen. Sera with equivocal or positive test results were retested with the Liaison® SARS-CoV-2 S1/S2 IgG (DiaSorin), which detects IgG against the spike (S)1 and S2 protein on the SARS-CoV-2 virus. In total, 98 women (adjusted prevalence 1.7%) had SARS CoV-2 antibodies. The adjusted seroprevalence increased from 0.3% (1/445) in December 2019 to 5.7% (21/418) in December 2020. Out of the 98 seropositive women, 36 (36.7%) had serological signs of current SARS-CoV-2 infection at the time of serum sampling, and the incidence remained low during the study period. This study suggests that SARS CoV-2 was present in the first half of December 2019, 6 weeks before the first case was recognised in Norway. The low occurrence of SARS-CoV-2 infection during 2020, may be explained by high compliance to extensive preventive measures implemented early in the epidemic. | |
dc.language | EN | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.title | Prevalence of antibodies against SARS-CoV-2 among pregnant women in Norway during the period December 2019 through December 2020 | |
dc.title.alternative | ENEngelskEnglishPrevalence of antibodies against SARS-CoV-2 among pregnant women in Norway during the period December 2019 through December 2020 | |
dc.type | Journal article | |
dc.creator.author | Eskild, Anne | |
dc.creator.author | Mørkrid, Lars | |
dc.creator.author | Mortensen, Siri Beisland | |
dc.creator.author | Leegaard, Truls Michael | |
cristin.unitcode | 185,53,83,0 | |
cristin.unitname | Klinikk for kirurgiske fag | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 2024285 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Epidemiology and Infection&rft.volume=150:e28&rft.spage=1&rft.date=2022 | |
dc.identifier.jtitle | Epidemiology and Infection | |
dc.identifier.volume | 150 | |
dc.identifier.doi | https://doi.org/10.1017/S0950268822000073 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 0950-2688 | |
dc.type.version | PublishedVersion | |
cristin.articleid | e28 | |