dc.date.accessioned | 2023-02-09T18:07:09Z | |
dc.date.available | 2023-02-09T18:07:09Z | |
dc.date.created | 2021-01-13T16:42:50Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Fjell, Anders Martin Sørensen, Øystein Amlien, Inge Kasbohm Bartrés-Faz, David Brandmaier, Andreas M. Buchmann, Nikolaus Demuth, Ilja Drevon, Christian A Düzel, Sandra Ebmeier, Klaus Ghisletta, Paolo Idland, Ane-Victoria Kietzmann, Tim C Kievit, Rogier A. Kühn, Simone Lindenberger, Ulman Magnussen, Fredrik Macià Bros, Didac Mowinckel, Athanasia Monika Nyberg, Lars Erik Sexton, Claire E Sole-Padulles, Cristina Pudas, Sara Roe, James Michael Sederevicius, Donatas Suri, Sana Vidal-Piñeiro, Didac Wagner, Gerd Watne, Leiv Otto Westerhausen, Rene Zsoldos, Eniko Walhovd, Kristine B . Poor Self-Reported Sleep is Related to Regional Cortical Thinning in Aging but not Memory Decline-Results From the Lifebrain Consortium. Cerebral Cortex. 2020, 1-17 | |
dc.identifier.uri | http://hdl.handle.net/10852/99847 | |
dc.description.abstract | We examined whether sleep quality and quantity are associated with cortical and memory changes in cognitively healthy participants across the adult lifespan. Associations between self-reported sleep parameters (Pittsburgh Sleep Quality Index, PSQI) and longitudinal cortical change were tested using five samples from the Lifebrain consortium (n = 2205, 4363 MRIs, 18–92 years). In additional analyses, we tested coherence with cell-specific gene expression maps from the Allen Human Brain Atlas, and relations to changes in memory performance. “PSQI # 1 Subjective sleep quality” and “PSQI #5 Sleep disturbances” were related to thinning of the right lateral temporal cortex, with lower quality and more disturbances being associated with faster thinning. The association with “PSQI #5 Sleep disturbances” emerged after 60 years, especially in regions with high expression of genes related to oligodendrocytes and S1 pyramidal neurons. None of the sleep scales were related to a longitudinal change in episodic memory function, suggesting that sleep-related cortical changes were independent of cognitive decline. The relationship to cortical brain change suggests that self-reported sleep parameters are relevant in lifespan studies, but small effect sizes indicate that self-reported sleep is not a good biomarker of general cortical degeneration in healthy older adults. | |
dc.language | EN | |
dc.rights | Attribution-NonCommercial 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | |
dc.title | Poor Self-Reported Sleep is Related to Regional Cortical Thinning in Aging but not Memory Decline-Results From the Lifebrain Consortium | |
dc.title.alternative | ENEngelskEnglishPoor Self-Reported Sleep is Related to Regional Cortical Thinning in Aging but not Memory Decline-Results From the Lifebrain Consortium | |
dc.type | Journal article | |
dc.creator.author | Fjell, Anders Martin | |
dc.creator.author | Sørensen, Øystein | |
dc.creator.author | Amlien, Inge Kasbohm | |
dc.creator.author | Bartrés-Faz, David | |
dc.creator.author | Brandmaier, Andreas M. | |
dc.creator.author | Buchmann, Nikolaus | |
dc.creator.author | Demuth, Ilja | |
dc.creator.author | Drevon, Christian A | |
dc.creator.author | Düzel, Sandra | |
dc.creator.author | Ebmeier, Klaus | |
dc.creator.author | Ghisletta, Paolo | |
dc.creator.author | Idland, Ane-Victoria | |
dc.creator.author | Kietzmann, Tim C | |
dc.creator.author | Kievit, Rogier A. | |
dc.creator.author | Kühn, Simone | |
dc.creator.author | Lindenberger, Ulman | |
dc.creator.author | Magnussen, Fredrik | |
dc.creator.author | Macià Bros, Didac | |
dc.creator.author | Mowinckel, Athanasia Monika | |
dc.creator.author | Nyberg, Lars Erik | |
dc.creator.author | Sexton, Claire E | |
dc.creator.author | Sole-Padulles, Cristina | |
dc.creator.author | Pudas, Sara | |
dc.creator.author | Roe, James Michael | |
dc.creator.author | Sederevicius, Donatas | |
dc.creator.author | Suri, Sana | |
dc.creator.author | Vidal-Piñeiro, Didac | |
dc.creator.author | Wagner, Gerd | |
dc.creator.author | Watne, Leiv Otto | |
dc.creator.author | Westerhausen, Rene | |
dc.creator.author | Zsoldos, Eniko | |
dc.creator.author | Walhovd, Kristine B | |
cristin.unitcode | 185,53,63,10 | |
cristin.unitname | Avdeling for radiologi-nukleærmedisin | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.fulltext | original | |
cristin.qualitycode | 2 | |
dc.identifier.cristin | 1870862 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Cerebral Cortex&rft.volume=&rft.spage=1&rft.date=2020 | |
dc.identifier.jtitle | Cerebral Cortex | |
dc.identifier.volume | 31 | |
dc.identifier.issue | 4 | |
dc.identifier.startpage | 1953 | |
dc.identifier.endpage | 1969 | |
dc.identifier.doi | https://doi.org/10.1093/cercor/bhaa332 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 1047-3211 | |
dc.type.version | PublishedVersion | |
dc.relation.project | SIGMA2/NS9084S | |
dc.relation.project | SIGMA2/NS9737S | |
dc.relation.project | EC/H2020/732592 | |
dc.relation.project | ERC/725025 | |
dc.relation.project | ERC/313440 | |
dc.relation.project | NFR/262453 | |
dc.relation.project | ERC/283634 | |
dc.relation.project | NFR/249931 | |