dc.date.accessioned | 2023-01-21T18:01:49Z | |
dc.date.available | 2023-01-21T18:01:49Z | |
dc.date.created | 2022-08-31T09:50:40Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | Øvrebotten, Tarjei Myhre, Peder Langeland Grimsmo, Jostein Mecinaj, Albulena Trebinjac, Divna Nossen, Magnus Berger Andrup, Simon Johan Mattias Josefsen, Tony Andre Einvik, Gunnar Stavem, Knut Omland, Torbjørn Ingul, Charlotte Ingeborg Björk . Changes in cardiac structure and function from 3 to 12 months after hospitalization for COVID-19. Clinical Cardiology. 2022, 45(10), 1044-1052 | |
dc.identifier.uri | http://hdl.handle.net/10852/99051 | |
dc.description.abstract | Background
Cardiac function may be impaired during and early after hospitalization for COVID-19, but little is known about the progression of cardiac dysfunction and the association with postacute COVID syndrome (PACS).
Methods
In a multicenter prospective cohort study, patients who had been hospitalized with COVID-19 were enrolled and comprehensive echocardiography was performed 3 and 12 months after discharge. Twenty-four-hour electrocardiogram (ECG) was performed at 3 and 12 months in patients with arrhythmias at 3 months.
Results
In total, 182 participants attended the 3 and 12 months visits (age 58 ± 14 years, 59% male, body mass index 28.2 ± 4.2 kg/m2). Of these, 35 (20%) had severe COVID-19 (treatment in the intensive care unit) and 74 (52%) had self-reported dyspnea at 3 months. From 3 to 12 months there were no significant overall changes in any measures of left or right ventricle (LV; RV) structure and function (p > .05 for all), including RV strain (from 26.2 ± 3.9% to 26.5 ± 3.1%, p = .29) and LV global longitudinal strain (from 19.2 ± 2.3% to 19.3 ± 2.3%, p = .64). Changes in echocardiographic parameters from 3 to 12 months did not differ by COVID-19 severity or by the presence of persistent dyspnea (p > .05 for all). Among patients with arrhythmia at 3 months, there was no significant change in arrhythmia burden to 12 months.
Conclusion
Following COVID-19, cardiac structure and function remained unchanged from 3 to 12 months after the index hospitalization, irrespective of COVID-19 severity and presence of persistent dyspnea. These results suggest that progression of cardiac dysfunction after COVID-19 is rare and unlikely to play an important role in PACS. | |
dc.language | EN | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.title | Changes in cardiac structure and function from 3 to 12 months after hospitalization for COVID-19 | |
dc.title.alternative | ENEngelskEnglishChanges in cardiac structure and function from 3 to 12 months after hospitalization for COVID-19 | |
dc.type | Journal article | |
dc.creator.author | Øvrebotten, Tarjei | |
dc.creator.author | Myhre, Peder Langeland | |
dc.creator.author | Grimsmo, Jostein | |
dc.creator.author | Mecinaj, Albulena | |
dc.creator.author | Trebinjac, Divna | |
dc.creator.author | Nossen, Magnus Berger | |
dc.creator.author | Andrup, Simon Johan Mattias | |
dc.creator.author | Josefsen, Tony Andre | |
dc.creator.author | Einvik, Gunnar | |
dc.creator.author | Stavem, Knut | |
dc.creator.author | Omland, Torbjørn | |
dc.creator.author | Ingul, Charlotte Ingeborg Björk | |
cristin.unitcode | 185,90,0,0 | |
cristin.unitname | Universitetet i Oslo | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 2047440 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Clinical Cardiology&rft.volume=45&rft.spage=1044&rft.date=2022 | |
dc.identifier.jtitle | Clinical Cardiology | |
dc.identifier.volume | 45 | |
dc.identifier.issue | 10 | |
dc.identifier.startpage | 1044 | |
dc.identifier.endpage | 1052 | |
dc.identifier.doi | https://doi.org/10.1002/clc.23891 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 0160-9289 | |
dc.type.version | PublishedVersion | |