dc.date.accessioned | 2022-04-21T16:20:42Z | |
dc.date.available | 2022-04-21T16:20:42Z | |
dc.date.created | 2022-02-18T08:25:20Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Alidjanov, Jakhongir F. Cai, Tommaso Bartoletti, Riccardo Bonkat, Gernot Bruyere, Franck Köves, Bela Kulchavenya, Ekaterina Medina-Polo, José Naber, Kurt Perepanova, Tamara Pilatz, Adrian Tandogdu, Zafer Johansen, Truls Erik Bjerklund Wagenlehner, Florian M. . The negative aftermath of prostate biopsy: prophylaxis, complications and antimicrobial stewardship: results of the global prevalence study of infections in urology 2010-2019. World Journal of Urology. 2021 | |
dc.identifier.uri | http://hdl.handle.net/10852/93668 | |
dc.description.abstract | Abstract
Purpose
To evaluate and report the complications, and to analyse antimicrobial stewardship aspects following prostate biopsies (P-Bx) based on the data from a 9-year global study.
Methods
The primary outcome was to compare complications after P-Bx between patients of two cohorts: 2010–2014 and 2016–2019. Primary outcomes included symptoms of lower and severe/systemic urinary tract infection (LUTIS and SUTIS, respectively), and positive urine culture. Readmission to hospital after P-Bx, need for additional antimicrobial therapy, consumption of different antimicrobial agents for prophylaxis and therapy were evaluated. Students t test and chi-square test were used for comparative analyses.
Results
Outcome data were available for 1615 men. Fluoroquinolones-based prophylaxis rate increased from 72.0% in 2010–2014 to 78.6% in 2015–2019. Overall rates of complications increased from 6 to 11.7% including an increase in symptomatic complications from 4.7 to 10.2%, mainly due to an increase in LUTIS. Rates of patients seeking additional medical help in primary care after P-Bx increased from 7.4 to 14.4%; cases requiring post P-Bx antibiotic treatment increased from 6.1 to 9.7%, most of which received fluoroquinolones. Transperineal P-Bx was significantly associated with LUTIS. Following transrectal P-Bx, 2.8% developed febrile infections and 4.0% required hospitalisation. Two men (0.12%) died after transrectal P-Bx due to sepsis.
Conclusions
The rates of complications after P-Bx tended to increase in time, as well as rates of patients seeking additional medical help in the post-P-Bx period. To reduce the risk of infectious complications and to comply with the principles of antibiotic stewardship, clinicians should switch to the transperineal biopsy route. | |
dc.language | EN | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.title | The negative aftermath of prostate biopsy: prophylaxis, complications and antimicrobial stewardship: results of the global prevalence study of infections in urology 2010-2019 | |
dc.type | Journal article | |
dc.creator.author | Alidjanov, Jakhongir F. | |
dc.creator.author | Cai, Tommaso | |
dc.creator.author | Bartoletti, Riccardo | |
dc.creator.author | Bonkat, Gernot | |
dc.creator.author | Bruyere, Franck | |
dc.creator.author | Köves, Bela | |
dc.creator.author | Kulchavenya, Ekaterina | |
dc.creator.author | Medina-Polo, José | |
dc.creator.author | Naber, Kurt | |
dc.creator.author | Perepanova, Tamara | |
dc.creator.author | Pilatz, Adrian | |
dc.creator.author | Tandogdu, Zafer | |
dc.creator.author | Johansen, Truls Erik Bjerklund | |
dc.creator.author | Wagenlehner, Florian M. | |
cristin.unitcode | 185,53,48,11 | |
cristin.unitname | Avdeling for urologi | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 2 | |
dc.identifier.cristin | 2003138 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=World Journal of Urology&rft.volume=&rft.spage=&rft.date=2021 | |
dc.identifier.jtitle | World Journal of Urology | |
dc.identifier.volume | 39 | |
dc.identifier.issue | 9 | |
dc.identifier.startpage | 3423 | |
dc.identifier.endpage | 3432 | |
dc.identifier.doi | https://doi.org/10.1007/s00345-021-03614-8 | |
dc.identifier.urn | URN:NBN:no-96229 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 0724-4983 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/93668/1/Alidjanov2021_Article_TheNegativeAftermathOfProstate%2B%25281%2529.pdf | |
dc.type.version | PublishedVersion | |