Can We Cluster ICU Treatment Strategies for Traumatic Brain Injury by Hospital Treatment Preferences?
dc.date.accessioned | 2022-04-01T17:13:24Z | |
dc.date.available | 2022-04-01T17:13:24Z | |
dc.date.created | 2022-02-21T00:48:50Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Ceyisakar, Iris Huijben, Jilske A. Maas, Andrew I. R. Lingsma, Hester F. van Leeuwen, Nikki Andelic, Nada Andreassen, Lasse Anke, Audny Gabriele Wagner Frisvold, Shirin Helseth, Eirik Røe, Cecilie Røise, Olav Skandsen, Toril Vik, Anne Åkerlund, Cecilia Amrein, Krisztina Antoni, Anna Audibert, Gerard Azouvi, Philippe Azzolini, Maria luisa Bartels, Ronald Barzo, Pal Beauvais, Romuald Beer, Ronny Bellander, Bo-michael Belli, Antonio Benali, Habib Berardino, Maurizio Beretta, Luigi Blaabjerg, Morten Bragge, Peter Brazinova, Alexandra Brinck, Vibeke Brooker, Joanne Brorsson, Camilla Buki, Andras Bullinger, Monika Cabeleira, Manuel Caccioppola, Alessio Calappi, Emiliana Calvi, Maria rosa Cameron, Peter Lozano, Guillermo carbayo Carbonara, Marco Chevallard, Giorgio Chieregato, Arturo Citerio, Giuseppe Cnossen, Maryse Coburn, Mark . Can We Cluster ICU Treatment Strategies for Traumatic Brain Injury by Hospital Treatment Preferences?. Neurocritical Care. 2021 | |
dc.identifier.uri | http://hdl.handle.net/10852/93174 | |
dc.description.abstract | Abstract Background In traumatic brain injury (TBI), large between-center differences in treatment and outcome for patients managed in the intensive care unit (ICU) have been shown. The aim of this study is to explore if European neurotrauma centers can be clustered, based on their treatment preference in different domains of TBI care in the ICU. Methods Provider profiles of centers participating in the Collaborative European Neurotrauma Effectiveness Research in TBI study were used to assess correlations within and between the predefined domains: intracranial pressure monitoring, coagulation and transfusion, surgery, prophylactic antibiotics, and more general ICU treatment policies. Hierarchical clustering using Ward’s minimum variance method was applied to group data with the highest similarity. Heat maps were used to visualize whether hospitals could be grouped to uncover types of hospitals adhering to certain treatment strategies. Results Provider profiles were available from 66 centers in 20 different countries in Europe and Israel. Correlations within most of the predefined domains varied from low to high correlations (mean correlation coefficients 0.2–0.7). Correlations between domains were lower, with mean correlation coefficients of 0.2. Cluster analysis showed that policies could be grouped, but hospitals could not be grouped based on their preference. Conclusions Although correlations between treatment policies within domains were found, the failure to cluster hospitals indicates that a specific treatment choice within a domain is not a proxy for other treatment choices within or outside the domain. These results imply that studying the effects of specific TBI interventions on outcome can be based on between-center variation without being substantially confounded by other treatments. Trial registration We do not report the results of a health care intervention. | |
dc.language | EN | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.title | Can We Cluster ICU Treatment Strategies for Traumatic Brain Injury by Hospital Treatment Preferences? | |
dc.type | Journal article | |
dc.creator.author | Ceyisakar, Iris | |
dc.creator.author | Huijben, Jilske A. | |
dc.creator.author | Maas, Andrew I. R. | |
dc.creator.author | Lingsma, Hester F. | |
dc.creator.author | van Leeuwen, Nikki | |
dc.creator.author | Andelic, Nada | |
dc.creator.author | Andreassen, Lasse | |
dc.creator.author | Anke, Audny Gabriele Wagner | |
dc.creator.author | Frisvold, Shirin | |
dc.creator.author | Helseth, Eirik | |
dc.creator.author | Røe, Cecilie | |
dc.creator.author | Røise, Olav | |
dc.creator.author | Skandsen, Toril | |
dc.creator.author | Vik, Anne | |
dc.creator.author | Åkerlund, Cecilia | |
dc.creator.author | Amrein, Krisztina | |
dc.creator.author | Antoni, Anna | |
dc.creator.author | Audibert, Gerard | |
dc.creator.author | Azouvi, Philippe | |
dc.creator.author | Azzolini, Maria luisa | |
dc.creator.author | Bartels, Ronald | |
dc.creator.author | Barzo, Pal | |
dc.creator.author | Beauvais, Romuald | |
dc.creator.author | Beer, Ronny | |
dc.creator.author | Bellander, Bo-michael | |
dc.creator.author | Belli, Antonio | |
dc.creator.author | Benali, Habib | |
dc.creator.author | Berardino, Maurizio | |
dc.creator.author | Beretta, Luigi | |
dc.creator.author | Blaabjerg, Morten | |
dc.creator.author | Bragge, Peter | |
dc.creator.author | Brazinova, Alexandra | |
dc.creator.author | Brinck, Vibeke | |
dc.creator.author | Brooker, Joanne | |
dc.creator.author | Brorsson, Camilla | |
dc.creator.author | Buki, Andras | |
dc.creator.author | Bullinger, Monika | |
dc.creator.author | Cabeleira, Manuel | |
dc.creator.author | Caccioppola, Alessio | |
dc.creator.author | Calappi, Emiliana | |
dc.creator.author | Calvi, Maria rosa | |
dc.creator.author | Cameron, Peter | |
dc.creator.author | Lozano, Guillermo carbayo | |
dc.creator.author | Carbonara, Marco | |
dc.creator.author | Chevallard, Giorgio | |
dc.creator.author | Chieregato, Arturo | |
dc.creator.author | Citerio, Giuseppe | |
dc.creator.author | Cnossen, Maryse | |
dc.creator.author | Coburn, Mark | |
cristin.unitcode | 185,53,42,10 | |
cristin.unitname | Avdeling for fysikalsk medisin og rehabilitering | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 2003863 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Neurocritical Care&rft.volume=&rft.spage=&rft.date=2021 | |
dc.identifier.jtitle | Neurocritical Care | |
dc.identifier.pagecount | 11 | |
dc.identifier.doi | https://doi.org/10.1007/s12028-021-01386-y | |
dc.identifier.urn | URN:NBN:no-95752 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 1541-6933 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/93174/1/Ceyisakar2021_Article_CanWeClusterICUTreatmentStrate.pdf | |
dc.type.version | PublishedVersion |
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