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dc.date.accessioned2022-02-28T18:27:05Z
dc.date.available2022-02-28T18:27:05Z
dc.date.created2022-01-11T13:32:21Z
dc.date.issued2021
dc.identifier.citationPontzer, Herman Yamada, Yosuke Sagayama, Hiroyuki Ainslie, Philip N. Andersen, Lene Frost Anderson, Liam J. Arab, Lenore Baddou, Issaad Bedu-Addo, Kweku Blaak, Ellen E. Blanc, Stéphane Bonomi, Alberto Bouten, Carlijn V.C. Bovet, Pascal Buchowski, Maciej S. Butte, Nancy F. Camps, Stefan G.J.A. Close, Graeme L. Cooper, Jamie A. Cooper, Richard Das, Sai Krupa Dugas, Lara R. Ekelund, Ulf Entringer, Sonja Forrester, Terrence Fudge, Barry W. Goris, Annelies Gurven, Michael Hambly, Catherine El Hamdouchi, Asmaa Hoos, Marjije B. Hu, Sumei Joonas, Noorjehan Joosen, Annemiek M. Katzmarzyk, Peter Kempen, Kitty P. Kimura, Misaka Kraus, William E. Kushner, Robert F. Lambert, Estelle V. Leonard, William R. Lessan, Nader Martin, Corby K. Medin, Anine Christine Meijer, Erwin P. Morehen, James C. Morton, James P. Neuhouser, Marian L. Nicklas, Theresa A. Ojiambo, Robert M. Pietiläinen, Kirsi H. Pitsiladis, Yannis P. Plange-Rhule, Jacob Plasqui, Guy Prentice, Ross L. Rabinovich, Roberto A. Racette, Susan B. Raichlen, David A. Ravussin, Eric Reynolds, Rebecca M. Roberts, Susan B. Schuit, Albertine J. Sjödin, Anders Stice, Eric Urlacher, Samuel S. Valenti, Giulio Van Etten, Ludo M. Van Mil, Edgar A. Wells, Jonathan C.K. Wilson, George Wood, Brian M. Yanovski, Jack Yoshida, Tsukasa Zhang, Xueying Murphy-Alford, Alexia J. Loechl, Cornelia U. Luke, Amy Rood, Jennifer C. Schoeller, Dale A. Westerterp, Klaas R. Wong, William W. Speakman, John R. . Daily energy expenditure through the human life course. Science. 2021, 373(6556), 808-812
dc.identifier.urihttp://hdl.handle.net/10852/91622
dc.description.abstractTotal daily energy expenditure (“total expenditure”) reflects daily energy needs and is a critical variable in human health and physiology, but its trajectory over the life course is poorly studied. We analyzed a large, diverse database of total expenditure measured by the doubly labeled water method for males and females aged 8 days to 95 years. Total expenditure increased with fat-free mass in a power-law manner, with four distinct life stages. Fat-free mass–adjusted expenditure accelerates rapidly in neonates to ~50% above adult values at ~1 year; declines slowly to adult levels by ~20 years; remains stable in adulthood (20 to 60 years), even during pregnancy; then declines in older adults. These changes shed light on human development and aging and should help shape nutrition and health strategies across the life span.
dc.languageEN
dc.publisherAmerican Association for the Advancement of Science
dc.titleDaily energy expenditure through the human life course
dc.typeJournal article
dc.creator.authorPontzer, Herman
dc.creator.authorYamada, Yosuke
dc.creator.authorSagayama, Hiroyuki
dc.creator.authorAinslie, Philip N.
dc.creator.authorAndersen, Lene Frost
dc.creator.authorAnderson, Liam J.
dc.creator.authorArab, Lenore
dc.creator.authorBaddou, Issaad
dc.creator.authorBedu-Addo, Kweku
dc.creator.authorBlaak, Ellen E.
dc.creator.authorBlanc, Stéphane
dc.creator.authorBonomi, Alberto
dc.creator.authorBouten, Carlijn V.C.
dc.creator.authorBovet, Pascal
dc.creator.authorBuchowski, Maciej S.
dc.creator.authorButte, Nancy F.
dc.creator.authorCamps, Stefan G.J.A.
dc.creator.authorClose, Graeme L.
dc.creator.authorCooper, Jamie A.
dc.creator.authorCooper, Richard
dc.creator.authorDas, Sai Krupa
dc.creator.authorDugas, Lara R.
dc.creator.authorEkelund, Ulf
dc.creator.authorEntringer, Sonja
dc.creator.authorForrester, Terrence
dc.creator.authorFudge, Barry W.
dc.creator.authorGoris, Annelies
dc.creator.authorGurven, Michael
dc.creator.authorHambly, Catherine
dc.creator.authorEl Hamdouchi, Asmaa
dc.creator.authorHoos, Marjije B.
dc.creator.authorHu, Sumei
dc.creator.authorJoonas, Noorjehan
dc.creator.authorJoosen, Annemiek M.
dc.creator.authorKatzmarzyk, Peter
dc.creator.authorKempen, Kitty P.
dc.creator.authorKimura, Misaka
dc.creator.authorKraus, William E.
dc.creator.authorKushner, Robert F.
dc.creator.authorLambert, Estelle V.
dc.creator.authorLeonard, William R.
dc.creator.authorLessan, Nader
dc.creator.authorMartin, Corby K.
dc.creator.authorMedin, Anine Christine
dc.creator.authorMeijer, Erwin P.
dc.creator.authorMorehen, James C.
dc.creator.authorMorton, James P.
dc.creator.authorNeuhouser, Marian L.
dc.creator.authorNicklas, Theresa A.
dc.creator.authorOjiambo, Robert M.
dc.creator.authorPietiläinen, Kirsi H.
dc.creator.authorPitsiladis, Yannis P.
dc.creator.authorPlange-Rhule, Jacob
dc.creator.authorPlasqui, Guy
dc.creator.authorPrentice, Ross L.
dc.creator.authorRabinovich, Roberto A.
dc.creator.authorRacette, Susan B.
dc.creator.authorRaichlen, David A.
dc.creator.authorRavussin, Eric
dc.creator.authorReynolds, Rebecca M.
dc.creator.authorRoberts, Susan B.
dc.creator.authorSchuit, Albertine J.
dc.creator.authorSjödin, Anders
dc.creator.authorStice, Eric
dc.creator.authorUrlacher, Samuel S.
dc.creator.authorValenti, Giulio
dc.creator.authorVan Etten, Ludo M.
dc.creator.authorVan Mil, Edgar A.
dc.creator.authorWells, Jonathan C.K.
dc.creator.authorWilson, George
dc.creator.authorWood, Brian M.
dc.creator.authorYanovski, Jack
dc.creator.authorYoshida, Tsukasa
dc.creator.authorZhang, Xueying
dc.creator.authorMurphy-Alford, Alexia J.
dc.creator.authorLoechl, Cornelia U.
dc.creator.authorLuke, Amy
dc.creator.authorRood, Jennifer C.
dc.creator.authorSchoeller, Dale A.
dc.creator.authorWesterterp, Klaas R.
dc.creator.authorWong, William W.
dc.creator.authorSpeakman, John R.
cristin.unitcode185,51,0,0
cristin.unitnameInstitutt for medisinske basalfag
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode2
dc.identifier.cristin1978386
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Science&rft.volume=373&rft.spage=808&rft.date=2021
dc.identifier.jtitleScience
dc.identifier.volume373
dc.identifier.issue6556
dc.identifier.startpage808
dc.identifier.endpage812
dc.identifier.doihttps://doi.org/10.1126/science.abe5017
dc.identifier.urnURN:NBN:no-94199
dc.type.documentTidsskriftartikkel
dc.type.peerreviewedPeer reviewed
dc.source.issn0036-8075
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/91622/1/abe5017_CombinedPDF_v3.pdf
dc.type.versionAcceptedVersion
dc.relation.projectUIA/689019


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