dc.date.accessioned | 2022-02-26T16:15:20Z | |
dc.date.available | 2022-02-26T16:15:20Z | |
dc.date.created | 2021-02-06T12:40:02Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Korytowska, Magdalena Schwab, Gabriela Giglio, Daniel Hirsch, Jan-Micháel Holmberg, Erik Kjeller, Göran Sand, Lars Peter Wallström, Mats Öhman, Jenny Braz-Silva, Paulo Hasséus, Bengt . Patient-reported pain after surgical removal of leukoplakia–an observational 1-year follow-up study. Acta Odontologica Scandinavica. 2021 | |
dc.identifier.uri | http://hdl.handle.net/10852/91564 | |
dc.description.abstract | Objective
Oral leukoplakia (OL) presents as a white lesion of the oral mucosa and is not typically associated with the sensation of pain. OL should be surgically removed when possible because it is considered a potentially malignant oral disorder (PMOD). This study assessed the pain sensations experienced by patients in association with the occurrence and surgical treatment of OL.
Methods
Inclusion criteria were: a clinical diagnosis of OL; biopsy excision; and observation for at least 12 months in the ORA-LEU-CAN study. At the first visit, all the patients were asked about the occurrence of symptoms within the lesion. Ninety-four subjects were assessed over a period of 1 year. All patients underwent complete removal of OL. The patient cohort was divided into three sub-groups: (i) no pain before excision and at the 1-year follow-up; (ii) pain before excision; and (iii) pain at the 1-year follow-up.
Results
Overall, pain was reported by 21.3% of the patients at the study start whereas 13.8% of the patients reported pain 1 year after surgical treatment. Patient-reported pain from the lesion at study inclusion was significantly associated with lesions found on the lateral side of the tongue (p=.002). Pain reported by patients one year after surgery was significantly related to female gender (p=.038) and the presence of epithelial cell dysplasia (p=.022).
Conclusion
We conclude that surgical removal of OL results in a low risk of long-term post-surgical pain. However, OL located on the lateral side of the tongue and in OL with dysplasia are more likely to be associated with pain. | |
dc.language | EN | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.title | Patient-reported pain after surgical removal of leukoplakia–an observational 1-year follow-up study | |
dc.type | Journal article | |
dc.creator.author | Korytowska, Magdalena | |
dc.creator.author | Schwab, Gabriela | |
dc.creator.author | Giglio, Daniel | |
dc.creator.author | Hirsch, Jan-Micháel | |
dc.creator.author | Holmberg, Erik | |
dc.creator.author | Kjeller, Göran | |
dc.creator.author | Sand, Lars Peter | |
dc.creator.author | Wallström, Mats | |
dc.creator.author | Öhman, Jenny | |
dc.creator.author | Braz-Silva, Paulo | |
dc.creator.author | Hasséus, Bengt | |
cristin.unitcode | 185,16,15,0 | |
cristin.unitname | Institutt for oral biologi | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 1887268 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Acta Odontologica Scandinavica&rft.volume=&rft.spage=&rft.date=2021 | |
dc.identifier.jtitle | Acta Odontologica Scandinavica | |
dc.identifier.volume | 79 | |
dc.identifier.issue | 5 | |
dc.identifier.startpage | 383 | |
dc.identifier.endpage | 389 | |
dc.identifier.pagecount | 0 | |
dc.identifier.doi | https://doi.org/10.1080/00016357.2020.1869826 | |
dc.identifier.urn | URN:NBN:no-94165 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 0001-6357 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/91564/1/Patient%2Breported%2Bpain%2Bafter%2Bsurgical%2Bremoval%2Bof%2Bleukoplakia%2Ban%2Bobservational%2B1%2Byear%2Bfollow%2Bup%2Bstudy.pdf | |
dc.type.version | PublishedVersion | |