dc.date.accessioned | 2022-02-17T18:19:54Z | |
dc.date.available | 2022-02-17T18:19:54Z | |
dc.date.created | 2022-01-04T18:01:23Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Johansen, Silje Lægreid, Ingvild Jenssen Ernstsen, Siw Leiknes Azrakhsh, Nessar Ahmad Kittang, Astrid Marta Olsnes Lindås, Roald Gjertsen, Bjørn Tore Vetti, Nils Mørtberg, Trude Victoria Sørvoll, Ingvild Hausberg Holme, Pål Andre Ahlen, Maria Therese Reikvam, Håkon . Thrombosis and thrombocytopenia after HPV vaccination. Journal of Thrombosis and Haemostasis. 2021 | |
dc.identifier.uri | http://hdl.handle.net/10852/91054 | |
dc.description.abstract | Background
Vaccine-induced immune thrombotic thrombocytopenia (VITT) has so far only been reported after adenovirus vector severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines.
Objective
We report findings in a 25-year-old woman who presented with thrombocytopenia, venous thrombosis, elevated D-dimer levels, and high levels of platelet-activating antibodies to platelet factor 4-polyanion complexes 10 days after Gardasil 9 vaccination for human papillomavirus (HPV). The patient exhibited clinical and laboratory features in line with the recently defined VITT syndrome, described after adenoviral vector vaccination to prevent coronavirus disease 2019.
Conclusion
We report a case of VITT following HPV vaccination. This should raise awareness of the possibility of VITT also occurring after other vaccines, not exclusively adenoviral vector-based SARS-CoV-2 vaccines. | |
dc.language | EN | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.title | Thrombosis and thrombocytopenia after HPV vaccination | |
dc.type | Journal article | |
dc.creator.author | Johansen, Silje | |
dc.creator.author | Lægreid, Ingvild Jenssen | |
dc.creator.author | Ernstsen, Siw Leiknes | |
dc.creator.author | Azrakhsh, Nessar Ahmad | |
dc.creator.author | Kittang, Astrid Marta Olsnes | |
dc.creator.author | Lindås, Roald | |
dc.creator.author | Gjertsen, Bjørn Tore | |
dc.creator.author | Vetti, Nils | |
dc.creator.author | Mørtberg, Trude Victoria | |
dc.creator.author | Sørvoll, Ingvild Hausberg | |
dc.creator.author | Holme, Pål Andre | |
dc.creator.author | Ahlen, Maria Therese | |
dc.creator.author | Reikvam, Håkon | |
cristin.unitcode | 185,53,49,11 | |
cristin.unitname | Avdeling for blodsykdommer | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 2 | |
dc.identifier.cristin | 1974685 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal of Thrombosis and Haemostasis&rft.volume=&rft.spage=&rft.date=2021 | |
dc.identifier.jtitle | Journal of Thrombosis and Haemostasis | |
dc.identifier.pagecount | 0 | |
dc.identifier.doi | https://doi.org/10.1111/jth.15604 | |
dc.identifier.urn | URN:NBN:no-93669 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 1538-7933 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/91054/1/Thrombosis%2Band%2Bthrombocytopenia%2Bafter%2BHPV%2Bvaccination.pdf | |
dc.type.version | PublishedVersion | |