dc.date.accessioned | 2021-04-23T20:05:34Z | |
dc.date.available | 2021-04-23T20:05:34Z | |
dc.date.created | 2021-02-26T11:05:13Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Kokurewicz, Karolina Brunetti, Enrico Curcio, Alessandro Gamba, Davide Garolfi, Luca Gilardi, Antonio Senes, Eugenio Sjobak, Kyrre Ness Farabolini, Wilfrid Corsini, Roberto Jaroszynski, Dino Anthony . An experimental study of focused very high energy electron beams for radiotherapy. Communications Physics. 2021, 4 | |
dc.identifier.uri | http://hdl.handle.net/10852/85521 | |
dc.description.abstract | Abstract Very high energy electron (VHEE) beams have been proposed as an alternative radiotherapy modality to megavoltage photons; they penetrate deeply without significant scattering in inhomogeneous tissue because of their high relativistic inertia. However, the depth dose distribution of a single, collimated VHEE beam is quasi-uniform, which can lead to healthy tissue being overexposed. This can be largely overcome by focusing the VHEE beam to a small spot. Here, we present experiments to demonstrate focusing as a means of concentrating dose into small volumetric elements inside a target. We find good agreement between measured dose distributions and Monte Carlo simulations. Focused radiation beams could be used to precisely target tumours or hypoxic regions of a tumour, which would enhance the efficacy of radiotherapy. The development of new accelerator technologies may provide future compact systems for delivering these focused beams to tumours, a concept that can also be extended to X-rays and hadrons. | |
dc.language | EN | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.title | An experimental study of focused very high energy electron beams for radiotherapy | |
dc.type | Journal article | |
dc.creator.author | Kokurewicz, Karolina | |
dc.creator.author | Brunetti, Enrico | |
dc.creator.author | Curcio, Alessandro | |
dc.creator.author | Gamba, Davide | |
dc.creator.author | Garolfi, Luca | |
dc.creator.author | Gilardi, Antonio | |
dc.creator.author | Senes, Eugenio | |
dc.creator.author | Sjobak, Kyrre Ness | |
dc.creator.author | Farabolini, Wilfrid | |
dc.creator.author | Corsini, Roberto | |
dc.creator.author | Jaroszynski, Dino Anthony | |
cristin.unitcode | 185,15,4,60 | |
cristin.unitname | Høyenergifysikk | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 1893987 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Communications Physics&rft.volume=4&rft.spage=&rft.date=2021 | |
dc.identifier.jtitle | Communications Physics | |
dc.identifier.volume | 4 | |
dc.identifier.issue | 1 | |
dc.identifier.pagecount | 7 | |
dc.identifier.doi | https://doi.org/10.1038/s42005-021-00536-0 | |
dc.identifier.urn | URN:NBN:no-88179 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 2399-3650 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/85521/2/s42005-021-00536-0.pdf | |
dc.type.version | PublishedVersion | |
cristin.articleid | 33 | |