dc.date.accessioned | 2021-03-14T21:05:23Z | |
dc.date.available | 2021-03-14T21:05:23Z | |
dc.date.created | 2020-03-27T12:19:36Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Martîn, Ruth Martîn Stonyte, Vilte Lopez Aviles, Sandra . Protein phosphatases in G1 regulation. International Journal of Molecular Sciences. 2020, 21:395(2), 1-15 | |
dc.identifier.uri | http://hdl.handle.net/10852/84038 | |
dc.description.abstract | Eukaryotic cells make the decision to proliferate, to differentiate or to cease dividing during G1, before passage through the restriction point or Start. Keeping cyclin-dependent kinase (CDK) activity low during this period restricts commitment to a new cell cycle and is essential to provide the adequate timeframe for the sensing of environmental signals. Here, we review the role of protein phosphatases in the modulation of CDK activity and as the counteracting force for CDK-dependent substrate phosphorylation, in budding and fission yeast. Moreover, we discuss recent findings that place protein phosphatases in the interface between nutritional signalling pathways and the cell cycle machinery. | |
dc.language | EN | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.title | Protein phosphatases in G1 regulation | |
dc.type | Journal article | |
dc.creator.author | Martîn, Ruth Martîn | |
dc.creator.author | Stonyte, Vilte | |
dc.creator.author | Lopez Aviles, Sandra | |
cristin.unitcode | 185,57,53,0 | |
cristin.unitname | Sandra Lopez-Aviles Group - Cell Cycle Regulations | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 1803926 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=International Journal of Molecular Sciences&rft.volume=21:395&rft.spage=1&rft.date=2020 | |
dc.identifier.jtitle | International Journal of Molecular Sciences | |
dc.identifier.volume | 21 | |
dc.identifier.issue | 2 | |
dc.identifier.doi | https://doi.org/10.3390/ijms21020395 | |
dc.identifier.urn | URN:NBN:no-86771 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 1422-0067 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/84038/1/ijms-21-00395.pdf | |
dc.type.version | PublishedVersion | |
cristin.articleid | 395 | |
dc.relation.project | NFR/187615 | |