dc.date.accessioned | 2021-03-10T20:30:56Z | |
dc.date.available | 2021-03-10T20:30:56Z | |
dc.date.created | 2020-09-30T11:00:08Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Sævik, Marte Beitnes, Jan Otto Aaberge, Lars Halvorsen, Per Steinar . Safety and feasibility of dobutamine stress echocardiography in symptomatic high gradient aortic stenosis patients scheduled for transcatheter aortic valve implantation. Journal of Clinical Ultrasound. 2020 | |
dc.identifier.uri | http://hdl.handle.net/10852/83865 | |
dc.description.abstract | Purpose
We aimed to study the safety and feasibility of low‐dose dobutamine stress echocardiography in a symptomatic high gradient aortic stenosis population scheduled for transfemoral transcatheter aortic valve implantation (TAVI) and to quantify left ventricular (LV) flow reserve.
Methods
Fifty patients underwent dobutamine stress echocardiography with 5 minutes increments of 5 μg/kg/min up to 20 μg/kg/min until the heart rate increased ≥20 beats/min from baseline or exceeded 100 beats/min. Other criteria for discontinuing the infusion were major adverse events: ventricular arrhythmia, persistent supraventricular arrhythmia, pulmonary edema, chest pain with significant ST‐changes, or minor events: ST‐changes, drop in systolic blood pressure >30 mmHg, mild chest pain, and/or dyspnea. LV flow reserve was defined as an increase in stroke volume ≥20% during the test.
Results
Of 50 patients, 45 completed the test according to protocol. No patient had major adverse event. Five patients experienced minor side effects: mild chest pain/dyspnea in three, self‐terminating atrial flutter in one, and decrease in blood pressure in one. Significant LV flow reserve was observed in 20 patients (40%).
Conclusion
Low‐dose dobutamine stress test appeared safe and feasible patients with high gradient aortic stenosis, and showed LV flow reserve in a minority of them. | |
dc.language | EN | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.title | Safety and feasibility of dobutamine stress echocardiography in symptomatic high gradient aortic stenosis patients scheduled for transcatheter aortic valve implantation | |
dc.type | Journal article | |
dc.creator.author | Sævik, Marte | |
dc.creator.author | Beitnes, Jan Otto | |
dc.creator.author | Aaberge, Lars | |
dc.creator.author | Halvorsen, Per Steinar | |
cristin.unitcode | 185,53,60,11 | |
cristin.unitname | Intervensjonssenteret | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 1835385 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal of Clinical Ultrasound&rft.volume=&rft.spage=&rft.date=2020 | |
dc.identifier.jtitle | Journal of Clinical Ultrasound | |
dc.identifier.volume | 49 | |
dc.identifier.issue | 1 | |
dc.identifier.startpage | 38 | |
dc.identifier.endpage | 48 | |
dc.identifier.pagecount | 0 | |
dc.identifier.doi | https://doi.org/10.1002/jcu.22915 | |
dc.identifier.urn | URN:NBN:no-86592 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 0091-2751 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/83865/1/S%25C3%25A6vik%2Bet%2Bal.pdf | |
dc.type.version | PublishedVersion | |