dc.date.accessioned | 2021-02-10T20:52:36Z | |
dc.date.available | 2021-12-10T23:45:40Z | |
dc.date.created | 2020-12-18T13:01:30Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Knudsen, Markus Dines Botteri, Edoardo Holme, Øyvind Hjartåker, Anette Song, Mingyang Thiis-Evensen, Espen Norvard, Espen Schult, Anna Lisa Randel, Kristin Ranheim Hoff, Geir Berstad, Paula . Association between lifestyle and site-specific advanced colorectal lesions in screening with faecal immunochemical test and sigmoidoscopy. Digestive and Liver Disease. 2020, 1-7 | |
dc.identifier.uri | http://hdl.handle.net/10852/83118 | |
dc.description.abstract | Background: Lifestyle factors may help to identify individuals at high-risk for colorectal cancer (CRC). Aims: To examine the association between lifestyle, referral for follow-up colonoscopy and proximal neoplasia detection in CRC screening. Methods: In this observational study, 14,832 individuals aged 50-74 years were invited to faecal immunochemical test (FIT) or sigmoidoscopy screening. Advanced lesions (AL), including advanced adenomas, advanced serrated lesions and CRC were divided according to location: distal-only, or proximal with or without distal AL. We collected information on smoking habit, body mass index and alcohol intake through a questionnaire. Results: Out of 3,318 FIT and 2,988 sigmoidoscopy participants, 516 (16%) and 338 (11%), respectively, were referred for follow-up colonoscopy after a positive screening test. Two-hundred-and-fifty-six (4%) had distal-only and 119 (2%) proximal AL. In FIT participants, obesity and high alcohol intake were associated with proximal AL; odds ratio (95% confidence interval) 2.68 (1.36-5.26) and 2.16 (1.08-4.30), respectively. In sigmoidoscopy participants, current smoking was associated with proximal AL; 4.58 (2.24-9.38), and current smoking and obesity were associated with referral for colonoscopy; 2.80 (2.02-3.89) and 1.42 (1.01-2.00), respectively. Conclusion: Current smoking, obesity and high alcohol intake were associated with screen-detected proximal colorectal AL. Current smoking and obesity were associated with referral for follow-up colonoscopy in sigmoidoscopy screening. | |
dc.language | EN | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.title | Association between lifestyle and site-specific advanced colorectal lesions in screening with faecal immunochemical test and sigmoidoscopy | |
dc.type | Journal article | |
dc.creator.author | Knudsen, Markus Dines | |
dc.creator.author | Botteri, Edoardo | |
dc.creator.author | Holme, Øyvind | |
dc.creator.author | Hjartåker, Anette | |
dc.creator.author | Song, Mingyang | |
dc.creator.author | Thiis-Evensen, Espen | |
dc.creator.author | Norvard, Espen | |
dc.creator.author | Schult, Anna Lisa | |
dc.creator.author | Randel, Kristin Ranheim | |
dc.creator.author | Hoff, Geir | |
dc.creator.author | Berstad, Paula | |
cristin.unitcode | 185,52,11,0 | |
cristin.unitname | Avdeling for helseledelse og helseøkonomi | |
cristin.ispublished | true | |
cristin.fulltext | postprint | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 1861583 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Digestive and Liver Disease&rft.volume=&rft.spage=1&rft.date=2020 | |
dc.identifier.jtitle | Digestive and Liver Disease | |
dc.identifier.startpage | 1 | |
dc.identifier.endpage | 7 | |
dc.identifier.doi | https://doi.org/10.1016/j.dld.2020.11.021 | |
dc.identifier.urn | URN:NBN:no-85887 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 1590-8658 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/83118/2/Manuscript_Anatomicsite_141020.pdf | |
dc.type.version | AcceptedVersion | |