Original version
Proceedings of the National Academy of Sciences of the United States of America. 2020, 117 (48), 30088-30095, DOI: https://doi.org/10.1073/pnas.1907377117
Abstract
Deep learning, due to its unprecedented success in tasks such as image classification, has emerged as a new tool in image reconstruction with potential to change the field. In this paper we demonstrate a crucial phenomenon: deep learning typically yields unstable methods for image reconstruction. The instabilities usually occur in several forms: (1) certain tiny, almost undetectable perturbations, both in the image and sampling domain, may result in severe artefacts in the reconstruction, (2) a small structural change, for example a tumour, may not be captured in the reconstructed image and (3) (a counterintuitive type of instability) more samples may yield poorer performance. Our new stability test with algorithms and easy to use software detects the instability phenomena. The test is aimed at researchers to test their networks for instabilities and for government agencies, such as the Food and Drug Administration (FDA), to secure safe use of deep learning methods.