dc.date.accessioned | 2020-11-24T20:13:32Z | |
dc.date.available | 2020-11-24T20:13:32Z | |
dc.date.created | 2020-11-05T15:12:34Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Møller, Peter Azqueta, Amaya Boutet-Robinet, Elisa Koppen, Gudrun Bonassi, Stefano Milic, Mirta Gajski, Goran Costa, Solange Teixeira, João Paulo Pereira, Cristiana Costa Dusinska, Maria Godschalk, Roger Brunborg, Gunnar Gutzkow, Kristine Bjerve Giovannelli, Lisa Cooke, Marcus S. Richling, Elke Laffon, Blanca Valdiglesias, Vanessa Basaran, Nursen Del Bo, Cristian Zegura, Bojana Novak, Matjaz Stopper, Helga Vodicka, Pavel Vodenkova, Sona de Andrade, Vanessa Moraes Srámková, Monika Gábelová, Alena Collins, Andrew Richard Langie, Sabine A.S. . Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results. Nature Protocols. 2020 | |
dc.identifier.uri | http://hdl.handle.net/10852/81168 | |
dc.description.abstract | The comet assay is a widely used test for the detection of DNA damage and repair activity. However, there are interlaboratory differences in reported levels of baseline and induced damage in the same experimental systems. These differences may be attributed to protocol differences, although it is difficult to identify the relevant conditions because detailed comet assay procedures are not always published. Here, we present a Consensus Statement for the Minimum Information for Reporting Comet Assay (MIRCA) providing recommendations for describing comet assay conditions and results. These recommendations differentiate between ‘desirable’ and ‘essential’ information: ‘essential’ information refers to the precise details that are necessary to assess the quality of the experimental work, whereas ‘desirable’ information relates to technical issues that might be encountered when repeating the experiments. Adherence to MIRCA recommendations should ensure that comet assay results can be easily interpreted and independently verified by other researchers. | |
dc.language | EN | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.title | Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results | |
dc.type | Journal article | |
dc.creator.author | Møller, Peter | |
dc.creator.author | Azqueta, Amaya | |
dc.creator.author | Boutet-Robinet, Elisa | |
dc.creator.author | Koppen, Gudrun | |
dc.creator.author | Bonassi, Stefano | |
dc.creator.author | Milic, Mirta | |
dc.creator.author | Gajski, Goran | |
dc.creator.author | Costa, Solange | |
dc.creator.author | Teixeira, João Paulo | |
dc.creator.author | Pereira, Cristiana Costa | |
dc.creator.author | Dusinska, Maria | |
dc.creator.author | Godschalk, Roger | |
dc.creator.author | Brunborg, Gunnar | |
dc.creator.author | Gutzkow, Kristine Bjerve | |
dc.creator.author | Giovannelli, Lisa | |
dc.creator.author | Cooke, Marcus S. | |
dc.creator.author | Richling, Elke | |
dc.creator.author | Laffon, Blanca | |
dc.creator.author | Valdiglesias, Vanessa | |
dc.creator.author | Basaran, Nursen | |
dc.creator.author | Del Bo, Cristian | |
dc.creator.author | Zegura, Bojana | |
dc.creator.author | Novak, Matjaz | |
dc.creator.author | Stopper, Helga | |
dc.creator.author | Vodicka, Pavel | |
dc.creator.author | Vodenkova, Sona | |
dc.creator.author | de Andrade, Vanessa Moraes | |
dc.creator.author | Srámková, Monika | |
dc.creator.author | Gábelová, Alena | |
dc.creator.author | Collins, Andrew Richard | |
dc.creator.author | Langie, Sabine A.S. | |
cristin.unitcode | 185,51,13,0 | |
cristin.unitname | Avdeling for ernæringsvitenskap | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 2 | |
dc.identifier.cristin | 1845352 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Nature Protocols&rft.volume=&rft.spage=&rft.date=2020 | |
dc.identifier.jtitle | Nature Protocols | |
dc.identifier.doi | https://doi.org/10.1038/s41596-020-0398-1 | |
dc.identifier.urn | URN:NBN:no-84237 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 1754-2189 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/81168/2/M%25C3%25B8ller%2Bet%2Bal_Nat%2BProtoc_2020.pdf | |
dc.type.version | PublishedVersion | |