| dc.date.accessioned | 2020-08-19T11:13:04Z | |
| dc.date.available | 2020-08-19T11:13:04Z | |
| dc.date.created | 2020-04-24T14:09:10Z | |
| dc.date.issued | 2020 | |
| dc.identifier.uri | http://hdl.handle.net/10852/78587 | |
| dc.language | EN | |
| dc.publisher | Faculty of Medicine, University of Oslo | |
| dc.relation.haspart | I. A three-dimensional ex vivo viability assay reveals a strong correlation between response to targeted inhibitors and mutation status in melanoma lymph node metastases. Flørenes VA, Flem-Karlsen K, McFadden E, Bergheim IR, Nygaard V, Nygård V, Farstad IN, Øy GF, Emilsen E, Giller-Fleten K, Ree AH, Flatmark K, Gullestad HP, Hermann R, Ryder T, Wernhoff P, Mælandsmo GM. Translational Oncology. 2019 Jul;12(7):951-958. The paper is included in the thesis, and is also available at: https://doi.org/10.1016/j.tranon.2019.04.001 | |
| dc.relation.haspart | II. Targeting AXL and the DNA damage response pathway as a novel therapeutic strategy in melanoma. Flem-Karlsen K, McFadden E, Omar N, Haugen MH, Øy GF, Ryder T, Gullestad HP, Hermann R, Mælandsmo GM, Flørenes VA. Molecular Cancer Therapeutics. 2020 19(3):895-905. An author version is included in the thesis, the published version is available at: https://doi.org/10.1158/1535-7163.MCT-19-0290 | |
| dc.relation.haspart | III. Soluble AXL as a marker of disease progression and survival in melanoma. Flem-Karlsen K, Nyakas M, McFadden E, Wernhoff P, Farstad IN, Flørenes VA, Mælandsmo GM. PLOS ONE. 2020, 15 (1):e0227187. An author version is included in the thesis, the published version is available at: https://doi.org/10.1371/journal.pone.0227187 | |
| dc.relation.haspart | IV. p38 MAPK activation through B7-H3-mediated DUSP10 repression promotes chemoresistance. Flem-Karlsen K, Tekle C, Øyjord T, Flørenes VA, Mælandsmo GM, Fodstad Ø, Nunes-Xavier CE. Scientific Reports. 2019 April;9(1):5839. The paper is included in the thesis, and is also available at: https://doi.org/10.1038/s41598-019-42303-w | |
| dc.relation.uri | https://doi.org/10.1016/j.tranon.2019.04.001 | |
| dc.relation.uri | https://doi.org/10.1158/1535-7163.MCT-19-0290 | |
| dc.relation.uri | https://doi.org/10.1371/journal.pone.0227187 | |
| dc.relation.uri | https://doi.org/10.1038/s41598-019-42303-w | |
| dc.title | Investigating therapeutic candidates and the use of preclinical models to predict treatment response in melanoma | |
| dc.type | Doctoral thesis | |
| dc.creator.author | Flem-Karlsen, Karine | |
| cristin.unitcode | 185,50,0,0 | |
| cristin.unitname | Det medisinske fakultet | |
| cristin.ispublished | true | |
| cristin.fulltext | original | |
| dc.identifier.cristin | 1807939 | |
| dc.identifier.pagecount | 192 | |
| dc.identifier.urn | URN:NBN:no-81673 | |
| dc.type.document | Doktoravhandling | |
| dc.source.isbn | 978-82-8377-614-0 | |
| dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/78587/1/Avhandling%2BKarine%2BFlem%2BKarlsen.pdf | |