dc.date.accessioned | 2020-08-12T18:32:05Z | |
dc.date.available | 2020-08-12T18:32:05Z | |
dc.date.created | 2020-07-03T18:24:31Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Banono, Nancy Saana Esguerra, Camila . Pharmacological Validation of the Prepulse Inhibition of Startle Response in Larval Zebrafish using a Commercial Automated System and Software. Journal of Visualized Experiments. 2020, 161 | |
dc.identifier.uri | http://hdl.handle.net/10852/78300 | |
dc.description.abstract | While there is an abundance of commercial and standardized automated systems and software for performing the prepulse inhibition (PPI) assay in rodents, to the best of our knowledge, all PPI assays performed in the zebrafish have, until now, been done using custom made systems which were only available to individual groups. This has thereby presented challenges, particularly with regard to issues of data reproducibility and standardization. In the present work, we generated a protocol that utilizes commercially available automated systems to pharmacologically validate the PPI assay in larval zebrafish. Consistent with published findings, we were able to replicate the results of apomorphine, haloperidol and ketamine on the PPI response of 6 days post-fertilization zebrafish larvae. | |
dc.language | EN | |
dc.publisher | Journal of Visualized Experiments | |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Unported | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/3.0/ | |
dc.title | Pharmacological Validation of the Prepulse Inhibition of Startle Response in Larval Zebrafish using a Commercial Automated System and Software | |
dc.type | Journal article | |
dc.creator.author | Banono, Nancy Saana | |
dc.creator.author | Esguerra, Camila | |
cristin.unitcode | 185,57,54,0 | |
cristin.unitname | Camila Esguerra Group - Chemical Neuroscience | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 1818520 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal of Visualized Experiments&rft.volume=161&rft.spage=&rft.date=2020 | |
dc.identifier.jtitle | Journal of Visualized Experiments | |
dc.identifier.volume | 161 | |
dc.identifier.issue | 161 | |
dc.identifier.doi | https://doi.org/10.3791/61423 | |
dc.identifier.urn | URN:NBN:no-81437 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 1940-087X | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/78300/2/Banono%2B%2526%2BEsguerra_JoVE%2B2020.pdf | |
dc.type.version | PublishedVersion | |
cristin.articleid | e61423 | |
dc.relation.project | NFR/ISP, BIOTEK2021/ DigiBrain | |