Minimally invasive versus open distal pancreatectomy for ductal adenocarcinoma (DIPLOMA): A pan-European propensity score matched study
dc.date.accessioned | 2020-07-16T17:55:48Z | |
dc.date.available | 2020-07-16T17:55:48Z | |
dc.date.created | 2020-03-16T12:27:55Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | van Hilst, Jony de Rooij, Thijs Klompmaker, Sjors Rawashdeh, Majd Aleotti, Francesca Al-Sarireh, Bilal Alseidi, Adnan Ateeb, Zeeshan Balzano, Gianpaolo Berrevoet, Frederik Björnsson, Bergthor Boggi, Ugo Busch, Olivier R. Butturini, Giovanni Casadei, Riccardo Del Chiaro, Marco Chikhladze, Sophia Cipriani, Federica Van Dam, Ronald Damoli, Isacco van Dieren, Susan Dokmak, Safi Edwin, Bjørn van Eijck, Casper Fabre, Jean-Marie Falconi, Massimo Farges, Olivier Fernández-Cruz, Laureano Forgione, Antonello Frigerio, Isabella Fuks, David Gavazzi, Francesca Gayet, Brice Giardino, Alessandro Groot Koerkamp, Bas Hackert, Thilo Hassenpflug, Matthias Kabir, Irfan Keck, Tobias Khatkov, Igor Kusar, Masa Lombardo, Carlo Marchegiani, Giovanni Marshall, Ryne Menon, Krish V. Montorsi, Marco Orville, Marion de Pastena, Matteo Pietrabissa, Andrea Poves, Ignaci Primrose, John Pugliese, Raffaele Ricci, Claudio Roberts, Keith Røsok, Bård Ingvald Sahakyan, Mushegh Sánchez-Cabús, Santiago Sandström, Per Scovel, Lauren Solaini, Leonardo Soonawalla, Zahir Souche, F. Régis Sutcliffe, Robert P. Tiberio, Guido A. Tomazic, Aleš Troisi, Roberto Wellner, Ulrich White, Steven Wittel, Uwe A. Zerbi, Alessandro Bassi, Claudio Besselink, Marc G. Abu Hilal, Mohammad . Minimally invasive versus open distal pancreatectomy for ductal adenocarcinoma (DIPLOMA): A pan-European propensity score matched study. Annals of Surgery. 2019, 269(1), 10-17 | |
dc.identifier.uri | http://hdl.handle.net/10852/78005 | |
dc.description.abstract | Objective: The aim of this study was to compare oncological outcomes after minimally invasive distal pancreatectomy (MIDP) with open distal pancreatectomy (ODP) in patients with pancreatic ductal adenocarcinoma (PDAC). Background: Cohort studies have suggested superior short-term outcomes of MIDP vs. ODP. Recent international surveys, however, revealed that surgeons have concerns about the oncological outcomes of MIDP for PDAC. Methods: This is a pan-European propensity score matched study including patients who underwent MIDP (laparoscopic or robot-assisted) or ODP for PDAC between January 1, 2007 and July 1, 2015. MIDP patients were matched to ODP patients in a 1:1 ratio. Main outcomes were radical (R0) resection, lymph node retrieval, and survival. Results: In total, 1212 patients were included from 34 centers in 11 countries. Of 356 (29%) MIDP patients, 340 could be matched. After matching, the MIDP conversion rate was 19% (n = 62). Median blood loss [200 mL (60–400) vs 300 mL (150–500), P = 0.001] and hospital stay [8 (6–12) vs 9 (7–14) days, P < 0.001] were lower after MIDP. Clavien-Dindo grade ≥3 complications (18% vs 21%, P = 0.431) and 90-day mortality (2% vs 3%, P > 0.99) were comparable for MIDP and ODP, respectively. R0 resection rate was higher (67% vs 58%, P = 0.019), whereas Gerota's fascia resection (31% vs 60%, P < 0.001) and lymph node retrieval [14 (8–22) vs 22 (14–31), P < 0.001] were lower after MIDP. Median overall survival was 28 [95% confidence interval (CI), 22–34] versus 31 (95% CI, 26–36) months (P = 0.929). Conclusions: Comparable survival was seen after MIDP and ODP for PDAC, but the opposing differences in R0 resection rate, resection of Gerota's fascia, and lymph node retrieval strengthen the need for a randomized trial to confirm the oncological safety of MIDP. | en_US |
dc.language | EN | |
dc.publisher | Lippincott Williams & Wilkins | |
dc.title | Minimally invasive versus open distal pancreatectomy for ductal adenocarcinoma (DIPLOMA): A pan-European propensity score matched study | en_US |
dc.type | Journal article | en_US |
dc.creator.author | van Hilst, Jony | |
dc.creator.author | de Rooij, Thijs | |
dc.creator.author | Klompmaker, Sjors | |
dc.creator.author | Rawashdeh, Majd | |
dc.creator.author | Aleotti, Francesca | |
dc.creator.author | Al-Sarireh, Bilal | |
dc.creator.author | Alseidi, Adnan | |
dc.creator.author | Ateeb, Zeeshan | |
dc.creator.author | Balzano, Gianpaolo | |
dc.creator.author | Berrevoet, Frederik | |
dc.creator.author | Björnsson, Bergthor | |
dc.creator.author | Boggi, Ugo | |
dc.creator.author | Busch, Olivier R. | |
dc.creator.author | Butturini, Giovanni | |
dc.creator.author | Casadei, Riccardo | |
dc.creator.author | Del Chiaro, Marco | |
dc.creator.author | Chikhladze, Sophia | |
dc.creator.author | Cipriani, Federica | |
dc.creator.author | Van Dam, Ronald | |
dc.creator.author | Damoli, Isacco | |
dc.creator.author | van Dieren, Susan | |
dc.creator.author | Dokmak, Safi | |
dc.creator.author | Edwin, Bjørn | |
dc.creator.author | van Eijck, Casper | |
dc.creator.author | Fabre, Jean-Marie | |
dc.creator.author | Falconi, Massimo | |
dc.creator.author | Farges, Olivier | |
dc.creator.author | Fernández-Cruz, Laureano | |
dc.creator.author | Forgione, Antonello | |
dc.creator.author | Frigerio, Isabella | |
dc.creator.author | Fuks, David | |
dc.creator.author | Gavazzi, Francesca | |
dc.creator.author | Gayet, Brice | |
dc.creator.author | Giardino, Alessandro | |
dc.creator.author | Groot Koerkamp, Bas | |
dc.creator.author | Hackert, Thilo | |
dc.creator.author | Hassenpflug, Matthias | |
dc.creator.author | Kabir, Irfan | |
dc.creator.author | Keck, Tobias | |
dc.creator.author | Khatkov, Igor | |
dc.creator.author | Kusar, Masa | |
dc.creator.author | Lombardo, Carlo | |
dc.creator.author | Marchegiani, Giovanni | |
dc.creator.author | Marshall, Ryne | |
dc.creator.author | Menon, Krish V. | |
dc.creator.author | Montorsi, Marco | |
dc.creator.author | Orville, Marion | |
dc.creator.author | de Pastena, Matteo | |
dc.creator.author | Pietrabissa, Andrea | |
dc.creator.author | Poves, Ignaci | |
dc.creator.author | Primrose, John | |
dc.creator.author | Pugliese, Raffaele | |
dc.creator.author | Ricci, Claudio | |
dc.creator.author | Roberts, Keith | |
dc.creator.author | Røsok, Bård Ingvald | |
dc.creator.author | Sahakyan, Mushegh | |
dc.creator.author | Sánchez-Cabús, Santiago | |
dc.creator.author | Sandström, Per | |
dc.creator.author | Scovel, Lauren | |
dc.creator.author | Solaini, Leonardo | |
dc.creator.author | Soonawalla, Zahir | |
dc.creator.author | Souche, F. Régis | |
dc.creator.author | Sutcliffe, Robert P. | |
dc.creator.author | Tiberio, Guido A. | |
dc.creator.author | Tomazic, Aleš | |
dc.creator.author | Troisi, Roberto | |
dc.creator.author | Wellner, Ulrich | |
dc.creator.author | White, Steven | |
dc.creator.author | Wittel, Uwe A. | |
dc.creator.author | Zerbi, Alessandro | |
dc.creator.author | Bassi, Claudio | |
dc.creator.author | Besselink, Marc G. | |
dc.creator.author | Abu Hilal, Mohammad | |
cristin.unitcode | 185,53,60,11 | |
cristin.unitname | Intervensjonssenteret | |
cristin.ispublished | true | |
cristin.fulltext | postprint | |
cristin.qualitycode | 2 | |
dc.identifier.cristin | 1801829 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Annals of Surgery&rft.volume=269&rft.spage=10&rft.date=2019 | |
dc.identifier.jtitle | Annals of Surgery | |
dc.identifier.volume | 269 | |
dc.identifier.issue | 1 | |
dc.identifier.startpage | 10 | |
dc.identifier.endpage | 17 | |
dc.identifier.doi | https://doi.org/10.1097/SLA.0000000000002561 | |
dc.identifier.urn | URN:NBN:no-81111 | |
dc.type.document | Tidsskriftartikkel | en_US |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 0003-4932 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/78005/1/van%2BHilst%2Bet%2Bal%2B-%2BDIPLOMA%2Bcohort%2Bstudy%2B-%2BManuscript%2B-%2Bv10-8.pdf | |
dc.type.version | AcceptedVersion |
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