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Common brain disorders are associated with heritable patterns of apparent aging of the brain

dc.date.accessioned2020-04-28T18:34:25Z
dc.date.available2020-04-28T18:34:25Z
dc.date.created2019-08-21T17:49:31Z
dc.date.issued2019
dc.identifier.citationKaufmann, Tobias van der Meer, Dennis Doan, Nhat Trung Schwarz, Emanuel Lund, Martina Jonette Agartz, Ingrid Alnæs, Dag Barch, Deanna M. Baur-Streubel, Ramona Bertolino, Alessandro Bettella, Francesco Beyer, Mona K. Bøen, Erlend Borgwardt, Stefan Brandt, Christine Lycke Buitelaar, Jan Celius, Elisabeth Gulowsen Cervenka, Simon Conzelmann, Annette Còrdova Palomera, Aldo Dale, Anders de Quervain, Dominique J.F. di Carlo, Pasquale Djurovic, Srdjan Dørum, Erlend Solberg Eisenacher, Sarah Elvsåshagen, Torbjørn Espeseth, Thomas Fatouros-Bergman, Helena Flyckt, Lena Franke, Barbara Frei, Oleksandr Haatveit, Beathe Håberg, Asta Harbo, Hanne Flinstad Hartman, Catharina A Heslenfeld, Dirk J Hoekstra, Pieter J Høgestøl, Einar August Jernigan, Terry L. Jonassen, Rune Jönsson, Erik Gunnar Kirsch, Peter Kłoszewska, Iwona Kolskår, Knut-Kristian Landrø, Nils Inge Le Hellard, Stephanie Lesch, Klaus-Peter Lovestone, Simon Lundervold, Arvid Lundervold, Astri Maglanoc, Luigi Angelo Malt, Ulrik Fredrik Mecocci, Patrizia Melle, Ingrid Meyer-Lindenberg, Andreas Moberget, Torgeir Norbom, Linn Christin Bonaventure Nordvik, Jan Egil Nyberg, Lars Oosterlaan, Jaap Papalino, Marco Papassotiropoulos, Andreas Pauli, Paul Pergola, Giulio Persson, Karin Ester Torun Richard, Geneviève Rokicki, Jaroslav Sanders, Anne-Marthe Selbæk, Geir Shadrin, Alexey A. Smeland, Olav Bjerkehagen Soininen, Hilkka Sowa, Piotr Steen, Vidar Martin Tsolaki, Magda Ulrichsen, Kristine Moe Vellas, Bruno Wang, Lei Westman, Eric Ziegler, Georg C. Zink, Mathias Andreassen, Ole Andreas Westlye, Lars Tjelta . Common brain disorders are associated with heritable patterns of apparent aging of the brain. Nature Neuroscience. 2019, 22(10), 1617-1623
dc.identifier.urihttp://hdl.handle.net/10852/74921
dc.description.abstractCommon risk factors for psychiatric and other brain disorders are likely to converge on biological pathways influencing the development and maintenance of brain structure and function across life. Using structural MRI data from 45,615 individuals aged 3–96 years, we demonstrate distinct patterns of apparent brain aging in several brain disorders and reveal genetic pleiotropy between apparent brain aging in healthy individuals and common brain disorders.
dc.languageEN
dc.titleCommon brain disorders are associated with heritable patterns of apparent aging of the brain
dc.typeJournal article
dc.creator.authorKaufmann, Tobias
dc.creator.authorvan der Meer, Dennis
dc.creator.authorDoan, Nhat Trung
dc.creator.authorSchwarz, Emanuel
dc.creator.authorLund, Martina Jonette
dc.creator.authorAgartz, Ingrid
dc.creator.authorAlnæs, Dag
dc.creator.authorBarch, Deanna M.
dc.creator.authorBaur-Streubel, Ramona
dc.creator.authorBertolino, Alessandro
dc.creator.authorBettella, Francesco
dc.creator.authorBeyer, Mona K.
dc.creator.authorBøen, Erlend
dc.creator.authorBorgwardt, Stefan
dc.creator.authorBrandt, Christine Lycke
dc.creator.authorBuitelaar, Jan
dc.creator.authorCelius, Elisabeth Gulowsen
dc.creator.authorCervenka, Simon
dc.creator.authorConzelmann, Annette
dc.creator.authorCòrdova Palomera, Aldo
dc.creator.authorDale, Anders
dc.creator.authorde Quervain, Dominique J.F.
dc.creator.authordi Carlo, Pasquale
dc.creator.authorDjurovic, Srdjan
dc.creator.authorDørum, Erlend Solberg
dc.creator.authorEisenacher, Sarah
dc.creator.authorElvsåshagen, Torbjørn
dc.creator.authorEspeseth, Thomas
dc.creator.authorFatouros-Bergman, Helena
dc.creator.authorFlyckt, Lena
dc.creator.authorFranke, Barbara
dc.creator.authorFrei, Oleksandr
dc.creator.authorHaatveit, Beathe
dc.creator.authorHåberg, Asta
dc.creator.authorHarbo, Hanne Flinstad
dc.creator.authorHartman, Catharina A
dc.creator.authorHeslenfeld, Dirk J
dc.creator.authorHoekstra, Pieter J
dc.creator.authorHøgestøl, Einar August
dc.creator.authorJernigan, Terry L.
dc.creator.authorJonassen, Rune
dc.creator.authorJönsson, Erik Gunnar
dc.creator.authorKirsch, Peter
dc.creator.authorKłoszewska, Iwona
dc.creator.authorKolskår, Knut-Kristian
dc.creator.authorLandrø, Nils Inge
dc.creator.authorLe Hellard, Stephanie
dc.creator.authorLesch, Klaus-Peter
dc.creator.authorLovestone, Simon
dc.creator.authorLundervold, Arvid
dc.creator.authorLundervold, Astri
dc.creator.authorMaglanoc, Luigi Angelo
dc.creator.authorMalt, Ulrik Fredrik
dc.creator.authorMecocci, Patrizia
dc.creator.authorMelle, Ingrid
dc.creator.authorMeyer-Lindenberg, Andreas
dc.creator.authorMoberget, Torgeir
dc.creator.authorNorbom, Linn Christin Bonaventure
dc.creator.authorNordvik, Jan Egil
dc.creator.authorNyberg, Lars
dc.creator.authorOosterlaan, Jaap
dc.creator.authorPapalino, Marco
dc.creator.authorPapassotiropoulos, Andreas
dc.creator.authorPauli, Paul
dc.creator.authorPergola, Giulio
dc.creator.authorPersson, Karin Ester Torun
dc.creator.authorRichard, Geneviève
dc.creator.authorRokicki, Jaroslav
dc.creator.authorSanders, Anne-Marthe
dc.creator.authorSelbæk, Geir
dc.creator.authorShadrin, Alexey A.
dc.creator.authorSmeland, Olav Bjerkehagen
dc.creator.authorSoininen, Hilkka
dc.creator.authorSowa, Piotr
dc.creator.authorSteen, Vidar Martin
dc.creator.authorTsolaki, Magda
dc.creator.authorUlrichsen, Kristine Moe
dc.creator.authorVellas, Bruno
dc.creator.authorWang, Lei
dc.creator.authorWestman, Eric
dc.creator.authorZiegler, Georg C.
dc.creator.authorZink, Mathias
dc.creator.authorAndreassen, Ole Andreas
dc.creator.authorWestlye, Lars Tjelta
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dc.identifier.cristin1717835
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Nature Neuroscience&rft.volume=22&rft.spage=1617&rft.date=2019
dc.identifier.jtitleNature Neuroscience
dc.identifier.volume22
dc.identifier.issue10
dc.identifier.startpage1617
dc.identifier.endpage1623
dc.identifier.doihttps://doi.org/10.1038/s41593-019-0471-7
dc.identifier.urnURN:NBN:no-78044
dc.type.documentTidsskriftartikkel
dc.type.peerreviewedPeer reviewed
dc.source.issn1097-6256
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/74921/2/KaufmannNatureNeuro.pdf
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dc.relation.projectNOTUR/NORSTORE/NS9666S
dc.relation.projectNOTUR/NORSTORE/NS9114K
dc.relation.projectNOTUR/NORSTORE/NN9114K
dc.relation.projectNFR/213837


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