dc.date.accessioned | 2019-12-07T20:24:27Z | |
dc.date.available | 2019-12-07T20:24:27Z | |
dc.date.created | 2018-07-10T20:00:37Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | Balaban, Gabriel Finsberg, Henrik Nicolay Funke, Simon Wolfgang Håland, Trine Synnøve Fink Hopp, Einar Sundnes, Joakim Wall, Samuel T Rognes, Marie Elisabeth . In vivo estimation of elastic heterogeneity in an infarcted human heart. Biomechanics and Modeling in Mechanobiology. 2018, 1-13 | |
dc.identifier.uri | http://hdl.handle.net/10852/71370 | |
dc.description.abstract | In myocardial infarction, muscle tissue of the heart is damaged as a result of ceased or severely impaired blood flow. Survivors have an increased risk of further complications, possibly leading to heart failure. Material properties play an important role in determining post-infarction outcome. Due to spatial variation in scarring, material properties can be expected to vary throughout the tissue of a heart after an infarction. In this study we propose a data assimilation technique that can efficiently estimate heterogeneous elastic material properties in a personalized model of cardiac mechanics. The proposed data assimilation is tested on a clinical dataset consisting of regional left ventricular strains and in vivo pressures during atrial systole from a human with a myocardial infarction. Good matches to regional strains are obtained, and simulated equi-biaxial tests are carried out to demonstrate regional heterogeneities in stress–strain relationships. A synthetic data test shows a good match of estimated versus ground truth material parameter fields in the presence of no to low levels of noise. This study is the first to apply adjoint-based data assimilation to the important problem of estimating cardiac elastic heterogeneities in 3-D from medical images. | |
dc.language | EN | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.title | In vivo estimation of elastic heterogeneity in an infarcted human heart | |
dc.type | Journal article | |
dc.creator.author | Balaban, Gabriel | |
dc.creator.author | Finsberg, Henrik Nicolay | |
dc.creator.author | Funke, Simon Wolfgang | |
dc.creator.author | Håland, Trine Synnøve Fink | |
dc.creator.author | Hopp, Einar | |
dc.creator.author | Sundnes, Joakim | |
dc.creator.author | Wall, Samuel T | |
dc.creator.author | Rognes, Marie Elisabeth | |
cristin.unitcode | 185,15,5,0 | |
cristin.unitname | Institutt for informatikk | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 1596679 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Biomechanics and Modeling in Mechanobiology&rft.volume=&rft.spage=1&rft.date=2018 | |
dc.identifier.jtitle | Biomechanics and Modeling in Mechanobiology | |
dc.identifier.volume | 17 | |
dc.identifier.issue | 5 | |
dc.identifier.startpage | 1 | |
dc.identifier.startpage | 1317 | |
dc.identifier.endpage | 13 | |
dc.identifier.endpage | 1329 | |
dc.identifier.doi | https://doi.org/10.1007/s10237-018-1028-5 | |
dc.identifier.urn | URN:NBN:no-74492 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 1617-7959 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/71370/2/BiomechandModelinMechs10237-018-1028-5.pdf | |
dc.type.version | PublishedVersion | |