dc.date.accessioned | 2019-01-17T14:43:10Z | |
dc.date.available | 2019-03-16T23:46:48Z | |
dc.date.created | 2018-07-22T14:12:12Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | Bjørnland, Kristin Hinna, Maren Aksnes, Gunnar Stensrud, Kjetil Juul Ertresvåg, Kjetil Østensen, Inger Anniken Bjørnstad Sanengen, Truls Line, Pål Dag Aagenæs, Ingegerd Aabakken, Lars Emblem, Ragnhild Almaas, Runar . Outcome for biliary atresia patients treated at a low-volume centre. Scandinavian Journal of Gastroenterology. 2018, 53(4), 471-474 | |
dc.identifier.uri | http://hdl.handle.net/10852/66190 | |
dc.description.abstract | Objectives: The importance of case load for treatment of extrahepatic biliary atresia (BA) is debated. The aim of this study was to register results of BA treatment in a small volume centre.
Methods: Retrospective chart review study of patients with BA treated from 2000 to 2017. The institutional review board approved the study.
Results: 45 babies were identified of which 42 (93%) are alive. 41 patients had a Kasai portoenterostomy (PE), two a hepaticojejunostomy and two a primary liver transplantation. The age at PE/hepaticojejunostomy was median 63 (4-145 days). Seven surgeons performed the operations, and the median duration of the diagnostic work-up was 8 (3-24) days. Clearance of jaundice was achieved in 23/43 (53%) babies, and 3- and 5-year native liver survival was 47% and 40% respectively. Clearance of jaundice post PE/hepaticojejunostomy was a strong predictor of native liver survival (adjusted OR: 0.027; 95%; P=0.009). Plasma level of conjugated bilirubin at time of referral was also a significant predictor of native liver survival (adjusted OR: 1.053; P=0.017).
Conclusion: A small volume centre may achieve satisfactory results for BA patients. The study has, however, identified factors that may further improve results; earlier referral, optimizing diagnostic work-up, and establishing one dedicated surgical team. | en_US |
dc.language | EN | |
dc.publisher | Informa Healthcare | |
dc.title | Outcome for biliary atresia patients treated at a low-volume centre | en_US |
dc.title.alternative | ENEngelskEnglishOutcome for biliary atresia patients treated at a low-volume centre | |
dc.type | Journal article | en_US |
dc.creator.author | Bjørnland, Kristin | |
dc.creator.author | Hinna, Maren | |
dc.creator.author | Aksnes, Gunnar | |
dc.creator.author | Stensrud, Kjetil Juul | |
dc.creator.author | Ertresvåg, Kjetil | |
dc.creator.author | Østensen, Inger Anniken Bjørnstad | |
dc.creator.author | Sanengen, Truls | |
dc.creator.author | Line, Pål Dag | |
dc.creator.author | Aagenæs, Ingegerd | |
dc.creator.author | Aabakken, Lars | |
dc.creator.author | Emblem, Ragnhild | |
dc.creator.author | Almaas, Runar | |
cristin.unitcode | 185,53,48,10 | |
cristin.unitname | Avdeling for gastro- og barnekirurgi | |
cristin.ispublished | true | |
cristin.fulltext | postprint | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 1598236 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Scandinavian Journal of Gastroenterology&rft.volume=53&rft.spage=471&rft.date=2018 | |
dc.identifier.jtitle | Scandinavian Journal of Gastroenterology | |
dc.identifier.volume | 53 | |
dc.identifier.issue | 4 | |
dc.identifier.startpage | 471 | |
dc.identifier.endpage | 474 | |
dc.identifier.doi | http://dx.doi.org/10.1080/00365521.2018.1439097 | |
dc.identifier.urn | URN:NBN:no-69398 | |
dc.type.document | Tidsskriftartikkel | en_US |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 0036-5521 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/66190/2/Outcome%2Bfor%2Bbiliary%2Batresia%2Bpatients%2Btreated%2Bat%2Ba%2Blow%2Bvolume%2Bcentre%2B%2B05%2B02%2B18%2Bdocx%2B%2Bwithout%2Bcorrections.pdf | |
dc.type.version | AcceptedVersion | |