dc.date.accessioned | 2018-08-14T12:40:42Z | |
dc.date.available | 2018-08-14T12:40:42Z | |
dc.date.created | 2018-05-27T15:58:11Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | Zotcheva, Ekaterina Selbæk, Geir Bjertness, Espen Ernstsen, Linda Strand, Bjørn Heine . Leisure-Time Physical Activity Is Associated With Reduced Risk of Dementia-Related Mortality in Adults With and Without Psychological Distress: The Cohort of Norway. Frontiers in Aging Neuroscience. 2018, 10 | |
dc.identifier.uri | http://hdl.handle.net/10852/62936 | |
dc.description.abstract | Background: Leisure-time physical activity (PA) has been proposed as a protective factor against dementia, whereas psychological distress is associated with an increased risk of dementia. We investigated the associations of leisure-time PA and psychological distress with dementia-related mortality, and whether the association between leisure-time PA and dementia-related mortality differs according to level of psychological distress.
Methods: 36,945 individuals from the Cohort of Norway aged 50-74 years at baseline (1994–2002) were included and followed up until January 1st 2015. Leisure-time PA and psychological distress were assessed through questionnaires, whereas dementia-related mortality was obtained through the Norwegian Cause of Death Registry. Adjusted Cox regression analyses were used to estimate hazard ratios (HR) and 95% confidence intervals (95%CI).
Results: Compared to inactivity, leisure-time PA was associated with a decreased risk of dementia-related mortality; low intensity leisure-time PA (HR = 0.73, 95% CI 0.59–0.89); high intensity leisure-time PA (HR = 0.61, 95%CI 0.49-0.77). A statistically significant difference in dementia-related mortality risk was observed between low and high intensity leisure-time PA (p < 0.05). Psychological distress was associated with an increased risk of dementia-related mortality (HR = 1.45, 95% CI 1.16–1.81). Among non-distressed, leisure-time PA was associated with a decreased dementia-related mortality risk; low intensity leisure-time PA (HR = 0.77, 95% CI 0.61–0.97); high intensity leisure-time PA (HR = 0.65, 95% CI 0.51–0.84). The same applied for those with psychological distress; low intensity leisure-time PA (HR = 0.57, 95% CI 0.35–0.94); high intensity leisure-time PA (HR = 0.42, 95% CI 0.22–0.82). The interaction between leisure-time PA and psychological distress on dementia-related mortality was not statistically significant (p = 0.38).
Conclusions: Participating in leisure-time PA was associated with a reduced risk of dementia-related mortality, whereas psychological distress was associated with an increased risk of dementia-related mortality. Leisure-time PA appears to be equally strongly related with dementia-related mortality among those with and without psychological distress, underlining the importance of leisure-time PA for various groups of middle-aged and older adults. | en_US |
dc.language | EN | |
dc.language.iso | en | en_US |
dc.publisher | Frontiers Research Foundation | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.title | Leisure-Time Physical Activity Is Associated With Reduced Risk of Dementia-Related Mortality in Adults With and Without Psychological Distress: The Cohort of Norway | en_US |
dc.title.alternative | ENEngelskEnglishLeisure-Time Physical Activity Is Associated With Reduced Risk of Dementia-Related Mortality in Adults With and Without Psychological Distress: The Cohort of Norway | |
dc.type | Journal article | en_US |
dc.creator.author | Zotcheva, Ekaterina | |
dc.creator.author | Selbæk, Geir | |
dc.creator.author | Bjertness, Espen | |
dc.creator.author | Ernstsen, Linda | |
dc.creator.author | Strand, Bjørn Heine | |
cristin.unitcode | 185,52,14,0 | |
cristin.unitname | Avdeling for samfunnsmedisin og global helse | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 1586993 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Frontiers in Aging Neuroscience&rft.volume=10&rft.spage=&rft.date=2018 | |
dc.identifier.jtitle | Frontiers in Aging Neuroscience | |
dc.identifier.volume | 10 | |
dc.identifier.doi | http://dx.doi.org/10.3389/fnagi.2018.00151 | |
dc.identifier.urn | URN:NBN:no-65511 | |
dc.type.document | Tidsskriftartikkel | en_US |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 1663-4365 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/62936/2/Final_FagiN_Zotcheva.pdf | |
dc.type.version | PublishedVersion | |
cristin.articleid | 151 | |
dc.relation.project | NFR/213805 | |