Nodding Syndrome in the Spotlight - Placing Recent Findings in Perspective.

Abstract

Nodding syndrome (NS) is a debated scientific topic. A recently published study suggests that NS is an autoimmune disorder based on findings of cross-reacting antibodies between neuronal structures and a protein present in Onchocerca volvulus (OV). In our opinion, the proposed causal relationship between OV infection and NS has yet to be demonstrated and, instead, OV infection in NS may be opportunistic. Spencer, Peter S., Erich Schmutzhard, and Andrea S. Winkler. "Nodding syndrome in the spotlight–placing recent findings in perspective." Trends in parasitology 33.7 (2017): 490-492. © 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license.