Hide metadata

dc.date.accessioned2017-06-26T11:37:04Z
dc.date.available2017-06-26T11:37:04Z
dc.date.created2017-01-09T15:53:08Z
dc.date.issued2016
dc.identifier.citationBjørnevik, Kjetil Riise, Trond Benjaminsen, Espen Celius, Elisabeth Gulowsen Dahl, Ole-Petter Kampman, Margitta Theodora Løken-Amsrud, Kristin Ingeleiv Midgard, Rune Myhr, Kjell-Morten Torkildsen, Øivind Vatne, Anita Grytten, Nina . Level of education and multiple sclerosis risk over a 50-year period: Registry-based sibling study. Multiple Sclerosis. 2016, 23, 213-219
dc.identifier.urihttp://hdl.handle.net/10852/55710
dc.description.abstractBackground: The conflicting results from studies on socioeconomic status (SES) and multiple sclerosis (MS) risk might be due to a change in the distribution of environmental exposures over time or to methodological limitations in previous research. Objective: To examine the association between SES and MS risk during 50 years. Methods: We included patients registered in Norwegian MS registries and prevalence studies born between 1930 and 1979, and identified their siblings and parents using the Norwegian Population Registry. Information on education was retrieved from the National Education Registry, categorized into four levels (primary, secondary, undergraduate and graduate) and compared in patients and siblings using conditional logistic regression. Results: A total of 4494 MS patients and 9193 of their siblings were included in the analyses. Level of education was inversely associated with MS risk (p trend < 0.001) with an odds ratio (OR) of 0.73 (95% confidence interval (CI): 0.59–0.90) when comparing the highest and lowest levels. The effect estimates did not vary markedly between participants born before or after the median year of birth (1958), but we observed a significant effect modification by parental education (p = 0.047). Conclusion: Level of education was inversely associated with MS risk, and the estimates were similar in the earliest and latest birth cohorts.en_US
dc.languageEN
dc.rightsAttribution 3.0 Unported
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/
dc.titleLevel of education and multiple sclerosis risk over a 50-year period: Registry-based sibling studyen_US
dc.typeJournal articleen_US
dc.creator.authorBjørnevik, Kjetil
dc.creator.authorRiise, Trond
dc.creator.authorBenjaminsen, Espen
dc.creator.authorCelius, Elisabeth Gulowsen
dc.creator.authorDahl, Ole-Petter
dc.creator.authorKampman, Margitta Theodora
dc.creator.authorLøken-Amsrud, Kristin Ingeleiv
dc.creator.authorMidgard, Rune
dc.creator.authorMyhr, Kjell-Morten
dc.creator.authorTorkildsen, Øivind
dc.creator.authorVatne, Anita
dc.creator.authorGrytten, Nina
cristin.unitcode185,52,11,0
cristin.unitnameAvdeling for helseledelse og helseøkonomi
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.cristin1423666
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Multiple Sclerosis&rft.volume=23&rft.spage=213&rft.date=2016
dc.identifier.jtitleMultiple Sclerosis
dc.identifier.volume23
dc.identifier.startpage213
dc.identifier.endpage219
dc.identifier.doihttp://dx.doi.org/10.1177/1352458516646863
dc.identifier.urnURN:NBN:no-58488
dc.type.documentTidsskriftartikkelen_US
dc.type.peerreviewedPeer reviewed
dc.source.issn1352-4585
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/55710/2/1352458516646863.pdf
dc.type.versionPublishedVersion


Files in this item

Appears in the following Collection

Hide metadata

Attribution 3.0 Unported
This item's license is: Attribution 3.0 Unported