dc.date.accessioned | 2017-05-24T11:31:50Z | |
dc.date.available | 2017-05-24T11:31:50Z | |
dc.date.created | 2017-01-16T12:31:10Z | |
dc.date.issued | 2016 | |
dc.identifier.citation | Fossum, Stine Vikanes, Åse Vigdis Næss, Øyvind Vos, Linda Grotmol, Tom Halvorsen, Sigrun . Hyperemesis gravidarum and long-term mortality: a population-based cohort study. BJOG: an International Journal of Obstetrics and Gynaecology. 2016 | |
dc.identifier.uri | http://hdl.handle.net/10852/55484 | |
dc.description.abstract | Objective
To investigate whether exposure to hyperemesis gravidarum (HG) is associated with increased maternal long-term mortality.
Results
Of 999 161 women with singleton births, 13 397 (1.3%) experienced HG. During a median follow up of 26 years (25 902 036 person-years), 43 470 women died (4.4%). Women exposed to HG had a lower risk of long-term all-cause mortality compared with women without HG (crude HR 0.82; 95% CI 0.75–0.90). When adjusting for confounders, this reduction was no longer significant (adjusted HR 0.92; 95% CI 0.84–1.01). Women exposed to HG had a similar risk of cardiovascular death as women not exposed (adjusted HR 1.04; 95% CI 0.83–1.29), but a lower long-term risk of death from cancer (adjusted HR 0.86; 95% CI 0.75–0.98).
Conclusion
In this large population-based cohort study, HG was not associated with an increased risk of long-term all-cause mortality. Women exposed to HG had no increase in mortality due to cardiovascular disease, but had a reduced risk of death from cancer. | en_US |
dc.language | EN | |
dc.publisher | Blackwell Science Ltd. | |
dc.relation.ispartof | Fossum, Stine (2019) Long-term cardiovascular risk in women with a history of hyperemesis gravidarum. Doctoral thesis. http://hdl.handle.net/10852/71752 | |
dc.relation.uri | http://hdl.handle.net/10852/71752 | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.title | Hyperemesis gravidarum and long-term mortality: a population-based cohort study | en_US |
dc.type | Journal article | en_US |
dc.creator.author | Fossum, Stine | |
dc.creator.author | Vikanes, Åse Vigdis | |
dc.creator.author | Næss, Øyvind | |
dc.creator.author | Vos, Linda | |
dc.creator.author | Grotmol, Tom | |
dc.creator.author | Halvorsen, Sigrun | |
cristin.unitcode | 185,53,11,10 | |
cristin.unitname | Hjertemedisinsk avdeling | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 2 | |
dc.identifier.cristin | 1428146 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=BJOG: an International Journal of Obstetrics and Gynaecology&rft.volume=&rft.spage=&rft.date=2016 | |
dc.identifier.jtitle | BJOG: an International Journal of Obstetrics and Gynaecology | |
dc.identifier.pagecount | 8 | |
dc.identifier.doi | http://dx.doi.org/10.1111/1471-0528.14454 | |
dc.identifier.urn | URN:NBN:no-58265 | |
dc.type.document | Tidsskriftartikkel | en_US |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 1470-0328 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/55484/1/Fossum_2016_Hyp.pdf | |
dc.type.version | PublishedVersion | |