Browsing Det matematisk-naturvitenskapelige fakultet by Author "Falnes, Pål"

Now showing items 1-4 of 4

  • ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA 
    Van den Born, Erwin; Vågbø, Cathrine Broberg; Songe-Møller, Lene; Leihne, VIbeke; Lien, Guro Flor; Leszczynska, G; Malkiewicz, A; Krokan, Hans Einar; Kirpekar, F; Klungland, Arne; Falnes, Pål (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
  • Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function 
    Malecki, Jedrzej Mieczyslaw; O'Donohue, Marie-Francoise; Kim, Yeji; Jakobsson, Magnus; Gessa, Luca; Pinto, Rita; Wu, Jie; Davydova, Erna; Moen, Anders; Olsen, Jesper V.; Thiede, Bernd; Gleizes, Pierre-Emmanuel; Leidel, Sebastian A.; Falnes, Pål (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Abstract Protein methylation occurs primarily on lysine and arginine, but also on some other residues, such as histidine. METTL18 is the last uncharacterized member of a group of human methyltransferases (MTases) ...
  • Roles of Trm9-and ALKBH8-like proteins in the formation of modified wobble uridines in Arabidopsis tRNA 
    Leihne, VIbeke; Kirpekar, F; Vågbø, Cathrine Broberg; Van den Born, Erwin; Krokan, Hans Einar; Grini, Paul Eivind; Meza, Trine Johansen; Falnes, Pål (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Uridine at the wobble position of tRNA is usually modified, and modification is required for accurate and efficient protein translation. In eukaryotes, wobble uridines are modified into 5-methoxycarbonylmethyluridine (mcm ...
  • The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage 
    Meza, Trine Johansen; Moen, Marivi; Vågbø, Cathrine Broberg; Krokan, Hans Einar; Klungland, Arne; Grini, Paul Eivind; Falnes, Pål (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
    The Escherichia coli AlkB protein (EcAlkB) is a DNA repair enzyme which reverses methylation damage such as 1-methyladenine (1-meA) and 3-methylcytosine (3-meC). The mammalian AlkB homologues ALKBH2 and ALKBH3 display ...