dc.contributor.author | Mai, Ngan Thi Kim | |
dc.date.accessioned | 2015-08-21T22:02:22Z | |
dc.date.available | 2015-08-21T22:02:22Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Mai, Ngan Thi Kim. C-C Bond formation in the purine 8-position by addition of allylmetals. Master thesis, University of Oslo, 2015 | |
dc.identifier.uri | http://hdl.handle.net/10852/44953 | |
dc.description.abstract | 8-Substituted purines have been extensively studied as for example anticancer or antiviral drugs. C-C Bond formation at the purine 8-position has been most commonly done via 8-halopurines, e.g. Pd-catalyzed coupling reactions. Meanwhile, direct conversion of purines not substituted at C-8 to 8-alkylpurines seems to be promising but there are few reports in the literature. In this thesis, addition of an allylmetallic reagent to 8-unsustituted purines followed by oxidation of the adduct to form 8-allylated purines will be discussed. | eng |
dc.language.iso | eng | |
dc.title | C-C Bond formation in the purine 8-position by addition of allylmetals | eng |
dc.type | Master thesis | |
dc.date.updated | 2015-08-21T22:03:00Z | |
dc.creator.author | Mai, Ngan Thi Kim | |
dc.identifier.urn | URN:NBN:no-49182 | |
dc.type.document | Masteroppgave | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/44953/1/Ngan_Mai_Master_Thesis.pdf | |