dc.date.accessioned | 2015-07-07T10:43:08Z | |
dc.date.available | 2015-07-07T10:43:08Z | |
dc.date.created | 2015-06-22T14:36:51Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Andersen, Jorunn Marie Herning, Hilde Aschim, Elin L. Hjelmesæth, Jøran Mala, Tom Hanevik, Hans Ivar Bungum, Mona Haugen, Trine B. Witczak, Oliwia . Body Mass Index Is Associated with Impaired Semen Characteristics and Reduced Levels of Anti-Müllerian Hormone across a Wide Weight Range. PLoS ONE. 2015 | |
dc.identifier.uri | http://hdl.handle.net/10852/44163 | |
dc.description.abstract | There is still controversy as to how body mass index (BMI) affects male reproduction. We investigated how BMI is associated with semen quality and reproductive hormones in 166 men, including 38 severely obese men. Standard semen analysis and sperm DNA integrity analysis were performed, and blood samples were analysed for reproductive hormones. Adjusted for age and time of abstinence, BMI was negatively associated with sperm concentration (B = -0.088, P = 0.009), total sperm count (B = -0.223, P = 0.001), progressive sperm motility (B = -0.675, P = 0.007), normal sperm morphology (B = -0.078, P = 0.001), and percentage of vital spermatozoa (B = -0.006, P = 0.027). A negative relationship was observed between BMI and total testosterone (B = -0.378, P < 0.001), sex hormone binding globulin (B = -0.572, P < 0.001), inhibin B (B = -3.120, P < 0.001) and anti-Müllerian hormone (AMH) (B = -0.009, P < 0.001). Our findings suggest that high BMI is negatively associated with semen characteristics and serum levels of AMH. | en_US |
dc.language | EN | |
dc.language.iso | en | en_US |
dc.publisher | Public Library of Science (PLoS) | |
dc.relation.ispartof | Andersen, Jorunn M. (2017) Semen quality in relation to body mass index, sperm fatty acid composition, and anti-Müllerian hormone. Doctoral thesis. http://urn.nb.no/URN:NBN:no-56836 | |
dc.relation.uri | http://urn.nb.no/URN:NBN:no-56836 | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.title | Body Mass Index Is Associated with Impaired Semen Characteristics and Reduced Levels of Anti-Müllerian Hormone across a Wide Weight Range | en_US |
dc.type | Journal article | en_US |
dc.creator.author | Andersen, Jorunn Marie | |
dc.creator.author | Herning, Hilde | |
dc.creator.author | Aschim, Elin L. | |
dc.creator.author | Hjelmesæth, Jøran | |
dc.creator.author | Mala, Tom | |
dc.creator.author | Hanevik, Hans Ivar | |
dc.creator.author | Bungum, Mona | |
dc.creator.author | Haugen, Trine B. | |
dc.creator.author | Witczak, Oliwia | |
cristin.unitcode | 185,53,11,16 | |
cristin.unitname | Avdeling for endokrinologi, sykelig overvekt og forebyggende medisin | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 1249926 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=PLoS ONE&rft.volume=&rft.spage=&rft.date=2015 | |
dc.identifier.jtitle | PLoS ONE | |
dc.identifier.volume | 10 | |
dc.identifier.issue | 6 | |
dc.identifier.doi | http://dx.doi.org/10.1371/journal.pone.0130210 | |
dc.identifier.urn | URN:NBN:no-48476 | |
dc.type.document | Tidsskriftartikkel | en_US |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 1932-6203 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/44163/2/Andersen%2B2015.pdf | |
dc.type.version | PublishedVersion | |
cristin.articleid | e0130210 | |