Browsing Kjemisk institutt by Author "Stocker, Achim"

Now showing items 1-3 of 3

  • Engineering of a functional γ-tocopherol transfer protein 
    Aeschimann, Walter; Kammer, Stephan; Staats, Stefanie; Schneider, Petra; Schneider, Gisbert; Rimbach, Gerald; Cascella, Michele; Stocker, Achim (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    α-tocopherol transfer protein (TTP) was previously reported to self-aggregate into 24-meric spheres (α-TTPS) and to possess transcytotic potency across mono-layers of human umbilical vein endothelial cells (HUVECs). In ...
  • Mechanisms of recognition and binding of α-TTP to the plasma membrane by multi-scale molecular dynamics simulations 
    Lamprakis, Christos; Stocker, Achim; Cascella, Michele (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    We used multiple sets of simulations both at the atomistic and coarse-grained level of resolution to investigate interaction and binding of α-tochoperol transfer protein (α-TTP) to phosphatidylinositol phosphate lipids ...
  • Self-assembly of alpha-tocopherol transfer protein nanoparticles: a patchy-protein model 
    Peltzer, Raphael Mathias; Kolli, Hima Bindu; Stocker, Achim; Cascella, Michele (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    We describe the mechanism of self-aggregation of α-tocopherol transfer protein into a spherical nanocage employing Monte Carlo simulations. The protein is modeled by a patchy coarse-grained representation, where the ...