Browsing Kjemisk institutt by Author "Riss, Patrick"
Now showing items 1-9 of 9
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Juri, Carlos; Kramer, Vasko; Riss, Patrick; Soza-Ried, Cristian; Haeger, Arlette; Pruzzo, Rossana; Rösch, Frank; Amaral, Horacio; Chana-Cuevas, Pedro (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Introduction Degeneration of dopaminergic, nigrostriatal neurons is the hallmark of Parkinson disease (PD), and PET quantification of dopamine transporters is a widely accepted method for differential diagnosis between ...
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Perez Garcia, Raul Manuel; Grønnevik, Gaute; Riss, Patrick (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)A Cu(I)-mediated fluoro-deamination method for nucleophilic radiofluorination was devised. The method affords fluorinated aromatic products directly from anilines under both no-carrier added and stoichiometric conditions. ...
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Bekker, Roberto Bartholomeus Wilhelmus; Fjellaksel, Richard; Hjornevik, Trine; Nuruddin, Syed; Rafique, Waqas; Hansen, Jørn H; Sundset, Rune; Haraldsen, Ira Hebold; Riss, Patrick (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)We report the synthesis, radiosynthesis and biological characterisation of two gonadotropin‐releasing hormone receptor (GnRH−R) antagonists with nanomolar binding affinity. A small library of GnRH−R antagonists was synthesised ...
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Fjellaksel, Richard; Moldes-Anaya, Angel; Vasskog, Terje; Oteiza, Ana; Martin-Armas, Maria Montserrat; Hjelstuen, Ole Kristian; Hansen, Jørn H; Riss, Patrick; Sundset, Rune (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)The increased expression of gonadotropin releasing hormone receptor (GnRH‐R) in brain has been strongly linked to Alzheimer disease. Therefore, the development of radiolabeled imaging agents for GnRH‐R is relevant for early ...
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Ott, Julian; Spilhaug, Mona M.; Maschauer, Simone; Rafique, Waqas; Jakobsson, Jimmy Erik; Hartvig, Karoline; Hübner, Harald; Gmeiner, Peter; Prante, Olaf; Riss, Patrick (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)The 3,4-dichloro-N-(1-(dimethylamino)cyclohexyl)methyl benzamide scaffold was studied as a template for 18F-positron emission tomography (18F-PET) radiotracer development emphasizing sensitivity to changes in opioid receptor ...
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Fjellaksel, Richard; Boomgaren, Marc; Sundset, Rune; Haraldsen, Ira Hebold; Hansen, Jørn H; Riss, Patrick (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)In this communication, we report the synthesis and characterization of a library of small molecule antagonists of the human gonadotropin releasing hormone receptor based upon the 2-(4-tert-butylphenyl)-4-piperazinyl-benzimidazole ...
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Alluri, Santosh Reddy; Pitman, Kathinka; Malinen, Eirik; Riss, Patrick (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)System xc‐ (Sxc‐) has emerged as a new biological target for PET studies to detect oxidative and excitotoxic stress. Notably, applications have, thus far, been limited to tumour imaging although Sxc‐) may play a major role ...
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Wærsted, Frøydis Meen; Riss, Patrick; Skipperud, Lindis (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)In recent years, there has been an increasing focus on the adverse environmental effects from naturally occurring radioactive materials (NORM). Acid rock drainage (ARD) produced by debris from mining and construction work ...
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Stefan, Katja; Leck, Lionel Yi Wen; Namasivayam, Vigneshwaran; Bascuñana, Pablo; Huang, Michael Li-Hsuan; Riss, Patrick; Pahnke, Jens; Jansson, Patric Jan; Stefan, Sven Marcel (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)