Browsing Kjemisk institutt by Author "Pedersen-Bjergaard, Stig"

Now showing items 1-3 of 3

  • 3D cell culture models and organ-on-a-chip: Meet separation science and mass spectrometry 
    Lin, Ann; Skottvoll, Frøydis Sved; Rayner, Simon; Pedersen-Bjergaard, Stig; Sullivan, Gareth; Krauss, Stefan; Wilson, Steven Ray Haakon; Harrison, Sean (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    In vitro derived simplified 3D representations of human organs or organ functionalities are predicted to play a major role in disease modeling, drug development, and personalized medicine, as they complement traditional ...
  • Direct Electromembrane Extraction based Mass Spectrometry: A Tool for Studying Drug Metabolism Properties of Liver Organoids 
    Wilson, Steven Ray Haakon; Krauss, Stefan Johannes Karl; Lundanes, Elsa; Skottvoll, Frøydis Sved; Bogen, Inger Lise; Pedersen-Bjergaard, Stig; Hansen, Frederik; Aizenshtadt, Aleksandra; Kutter, Jörg P.; Andersen, Jannike Mørch; Martinez, Mikel Amirola (Journal article / Tidsskriftartikkel / PublishedVersion, 2021)
    This work introduces a strategy for organoid analysis - direct Electromembrane Extraction based Mass Spectrometry (dEME-MS) – for coupling liver organoids with mass spectrometry (MS). dEME-MS comprises electrophoresis of ...
  • Electromembrane extraction and mass spectrometry for liver organoid drug metabolism studies 
    Skottvoll, Frøydis Sved; Hansen, Frederik; Harrison, Sean; Boger, Ida Caroline Sneis; Mrsa, Ago; Restan, Magnus Saed; Stein, Matthias; Lundanes, Elsa; Pedersen-Bjergaard, Stig; Aizenshtadt, Aleksandra; Krauss, Stefan; Sullivan, Gareth; Bogen, Inger Lise; Wilson, Steven Ray Haakon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Liver organoids are emerging tools for precision drug development and toxicity screening. We demonstrate that electromembrane extraction (EME) based on electrophoresis across an oil membrane is suited for segregating ...