Browsing Kjemisk institutt by Author "Olsen, Christine"
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Olsen, Christine (Doctoral thesis / Doktoravhandling, 2023)Understanding islet cell biology is important for multiple metabolic diseases, including diabetes and obesity. Stem cell-derived islet organoids (SC-islets) are cell models suitable for closing existing knowledge gaps ...
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Wilson, Steven Ray Haakon; Olsen, Christine; Lundanes, Elsa (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Nano liquid chromatography (nanoLC), with columns having an inner diameter (ID) of ≤100 μm, can provide enhanced sensitivity and enable analysis of limited samples. NanoLC has become an established tool in omics research, ...
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Olsen, Christine; Wang, Chencheng; Aizenshtadt, Aleksandra; Abadpour, Shadab; Lundanes, Elsa; Skottvoll, Frøydis Sved; Golovin, Alexey; Busek, Mathias; Krauss, Stefan Johannes Karl; Scholz, Hanne; Wilson, Steven Ray Haakon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Abstract For studying stem cell–derived islet organoids (SC‐islets) in an organ‐on‐chip (OoC) platform, we have developed a reversed‐phase liquid chromatography–tandem mass spectrometry (RPLC–MS/MS) method allowing for ...
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Olsen, Christine (Master thesis / Masteroppgave, 2019)A challenge in drug discovery is the identification of the drug target, called drug deconvolution. Additionally, off-target effects are considered as one of the reasons many developed drugs fail in the clinical trials. The ...