Browsing Kjemisk institutt by Author "Mahajan, Tushar R."
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Mahajan, Tushar R. (Doctoral thesis / Doktoravhandling, 2016)Resistance to chemotherapy and/or radiotherapy limits the effectiveness of cancer treatment. One factor that can contribute to resistance is the process of DNA repair. Among the different DNA repair pathways, the base ...
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Synthetic Routes to N-9 Alkylated 8-Oxoguanines; Weak Inhibitors of the Human DNA Glycosylase OGG1 Mahajan, Tushar R.; Ytre-Arne, Mari Eknes; Strøm-Andersen, Pernille; Dalhus, Bjørn; Gundersen, Lise-Lotte (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)The human 8-oxoguanine DNA glycosylase OGG1 is involved in base excision repair (BER), one of several DNA repair mechanisms that may counteract the effects of chemo- and radiation therapy for the treatment of cancer. We ...