Browsing Kjemisk institutt by Author "Lianto, Priscilia"

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  • ER-Negative Breast Cancer Is Highly Responsive to Cholesterol Metabolite Signalling 
    Hutchinson, Samantha A; Lianto, Priscilia; Røberg-Larsen, Hanne; Battaglia, Sebastiano; Hughes, Thomas A; Thorne, James L (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Interventions that alter cholesterol have differential impacts on hormone receptor positive- and negative-breast cancer risk and prognosis. This implies differential regulation or response to cholesterol within different ...
  • Liver x receptor alpha drives chemoresistance in response to side-chain hydroxycholesterols in triple negative breast cancer 
    Hutchinson, Samantha A.; Websdale, Alex; Cioccoloni, Giorgia; Røberg-Larsen, Hanne; Lianto, Priscilia; Kim, Baek; Rose, Ailsa; Soteriou, Chrysa; Pramanik, Arindam; Wastall, Laura M.; Williams, Bethany J.; Henn, Madeline A.; Chen, Joy J.; Ma, Liqian; Moore, J. Bernadette; Nelson, Erik; Hughes, Thomas A.; Thorne, James L. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Abstract Triple negative breast cancer (TNBC) is challenging to treat successfully because targeted therapies do not exist. Instead, systemic therapy is typically restricted to cytotoxic chemotherapy, which fails more often ...