Browsing Kjemisk institutt by Author "Jenssen, Håvard"

Now showing items 1-4 of 4

  • A biophysical study of the interactions between the antimicrobial peptide indolicidin and lipid model systems 
    Nielsen, Josefine Eilsø; Lind, Tania Kjellerup; Lone, Abdullah; Gerelli, Yuri; Hansen, Paul Robert; Jenssen, Håvard; Cardenas, Marite; Lund, Reidar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    The naturally occurring peptide indolicidin from bovine neutrophils exhibits strong biological activity against a broad spectrum of microorganisms. This is believed to arise from selective interactions with the negatively ...
  • Beyond structural models for the mode of action: How natural antimicrobial peptides affect lipid transport 
    Nielsen, Josefine Eilsø; Bjørnestad, Victoria Ariel; Pipich, Vitaliy; Jenssen, Håvard; Lund, Reidar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Hypothesis: Most textbook models for antimicrobial peptides (AMP) mode of action are focused on structural effects and pore formation in lipid membranes, while these deformations have been shown to require high concentrations ...
  • Halogenation as a tool to tune antimicrobial activity of peptoids 
    Molchanova, Natalia; Nielsen, Josefine Eilsø; Sørensen, Kristian B; Krishna, Bala; Hansen, Paul Robert; Lund, Reidar; Barron, Annelise E.; Jenssen, Håvard (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract Antimicrobial peptides have attracted considerable interest as potential new class of antibiotics against multi-drug resistant bacteria. However, their therapeutic potential is limited, in part due to ...
  • Real-Time Monitoring of Multitarget Antimicrobial Mechanisms of Peptoids Using Label-Free Imaging with Optical Diffraction Tomography 
    Kim, Minsang; Cheon, Yeongmi; Shin, Dongmin; Choi, Jieun; Nielsen, Josefine Eilsø; Jeong, Myeong Seon; Nam, Ho Yeon; Kim, Sung-Hak; Lund, Reidar; Jenssen, Håvard; Barron, Annelise E.; Lee, Seongsoo; Seo, Jiwon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Antimicrobial peptides (AMPs) are promising therapeutics in the fight against multidrug‐resistant bacteria. As a mimic of AMPs, peptoids with N ‐substituted glycine backbone have been utilized for antimicrobials ...