Browsing Kjemisk institutt by Author "Gundersen, Lise-Lotte"

Now showing items 1-4 of 4

  • Bioactive Metabolites of Marine Origin Have Unusual Effects on Model Membrane Systems 
    Jakubec, Martin; Totland, Christian; Rise, Frode; Chamgordani, Elahe Jafari; Paulsen, Britt; Maes, Louis; Matheeussen, An; Gundersen, Lise-Lotte; Halskau, Øyvind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Marine sponges and soft corals have yielded novel compounds with antineoplastic and antimicrobial activities. Their mechanisms of action are poorly understood, and in most cases, little relevant experimental evidence is ...
  • Selective C-7 Functionalization of Phenanthridines by Microwave-Assisted Claisen Rearrangements of 8-Allyloxyphenanthridines 
    Lepsøe, Mathias Ryslett; Dalevold, Aleksander Granum; Gundersen, Lise-Lotte (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Carbon‐carbon bond formation in the phenanthridine 7‐position was achieved by microwave‐assisted Claisen rearrangement of 8‐allyloxyphenanthridines. The reactions took place with excellent regioselectivity and ...
  • Synthesis and antimicrobial activities of N6-hydroxyagelasine analogs and revision of the structure of ageloximes 
    Paulsen, Britt; Fredriksen, Kim Alex; Petersen, Dirk; Maes, Louis; Matheeussen, An; Naemi, Ali-Oddin; Scheie, Anne Aamdal; Simm, Roger; Ma, Rui; Wan, Baojie; Franzblau, Scott; Gundersen, Lise-Lotte (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    (+)-N6-Hydroxyagelasine D, the enantiomer of the proposed structure of (–)-ageloxime D, as well as N6-hydroxyagelasine analogs were synthesized by selective N-7 alkylation of N6-[tert-butyl(dimethyl)silyloxy]-9-methyl-9H ...
  • Synthetic Routes to N-9 Alkylated 8-Oxoguanines; Weak Inhibitors of the Human DNA Glycosylase OGG1 
    Mahajan, Tushar R.; Ytre-Arne, Mari Eknes; Strøm-Andersen, Pernille; Dalhus, Bjørn; Gundersen, Lise-Lotte (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    The human 8-oxoguanine DNA glycosylase OGG1 is involved in base excision repair (BER), one of several DNA repair mechanisms that may counteract the effects of chemo- and radiation therapy for the treatment of cancer. We ...