Browsing Kjemisk institutt by Author "Furse, Samuel Robert"

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  • Cholesterol-containing lipid nanodiscs promote an α-synuclein binding mode that accelerates oligomerization 
    Jakubec, Martin; Bariås, Espen; Furse, Samuel Robert; Govasli Larsen, Morten Andreas; George, Vinnit; Turcu, Diana Cornelia; Iashchishyn, Igor A.; Morozova-Roche, Ludmilla A.; Halskau, Øyvind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Dysregulation of the biosynthesis of cholesterol and other lipids has been implicated in many neurological diseases, including Parkinson's disease. Misfolding of α‐synuclein (α‐Syn), the main actor in Parkinson's disease, ...
  • The biosynthesis of phospholipids is linked to the cell cycle in a model eukaryote 
    Vitova, Milada; Lanta, Vojtech; Cizkova, Maria; Jakubec, Martin; Rise, Frode; Halskau, Øyvind; Bisova, Katerina; Furse, Samuel Robert (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    The structural challenges faced by eukaryotic cells through the cell cycle are key for understanding cell viability and proliferation. We tested the hypothesis that the biosynthesis of structural lipids is linked to the ...