Browsing Kjemisk institutt by Author "Brandtzæg, Ole Kristian Merkesvik"
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Hustoft, Hanne Kolsrud; Brandtzæg, Ole Kristian Merkesvik; Misaghian, Dorna; Røgeberg, Magnus; Torsetnes, Silje Bøen; Reubsaet, Leon; Wilson, Steven Ray Haakon; Greibrokk, Tyge; Lundanes, Elsa (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)Reliable, sensitive and automatable analytical methodology is of great value in e.g. cancer diagnostics. In this context, an on-line system for enzymatic cleavage of proteins, subsequent peptide separation by liquid ...
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Brandtzæg, Ole Kristian Merkesvik (Master thesis / Masteroppgave, 2014)Sample preparation in bottom-up proteomics consists of denaturation, reduction and alkylation of the proteins, before enzymatic digestion of the proteins into peptides. The rate limiting step is the enzymatic digestion, ...
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Hustoft, Hanne Kolsrud; Vehus, Tore; Brandtzæg, Ole Kristian Merkesvik; Krauss, Stefan; Greibrokk, Tyge; Wilson, Steven Ray Haakon; Lundanes, Elsa (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)A novel open tubular nanoproteomic platform featuring accelerated on-line protein digestion and high-resolution nano liquid chromatography mass spectrometry (LC-MS) has been developed. The platform features very narrow ...