Browsing Kjemisk institutt by Author "Boger, Ida Caroline Sneis"

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  • Determination of liver organoid- and spheroid induced drug metabolites using liquid chromatography-mass spectrometryRestricted Access 
    Boger, Ida Caroline Sneis (Master thesis / Masteroppgave, 2020)
    The liver is the main metabolizing organ in the human body, and several in vitro models have been developed to resemble hepatic drug metabolism. However, commonly used in vitro models such as human liver microsomes (HLMs), ...
  • Electromembrane extraction and mass spectrometry for liver organoid drug metabolism studies 
    Skottvoll, Frøydis Sved; Hansen, Frederik; Harrison, Sean; Boger, Ida Caroline Sneis; Mrsa, Ago; Restan, Magnus Saed; Stein, Matthias; Lundanes, Elsa; Pedersen-Bjergaard, Stig; Aizenshtadt, Aleksandra; Krauss, Stefan; Sullivan, Gareth; Bogen, Inger Lise; Wilson, Steven Ray Haakon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Liver organoids are emerging tools for precision drug development and toxicity screening. We demonstrate that electromembrane extraction (EME) based on electrophoresis across an oil membrane is suited for segregating ...
  • Scalable production of tissue-like vascularized liver organoids from human PSCs 
    Harrison, Sean Philip; Siller, Richard; Tanaka, Yoshiaki; Chollet Dugarte, Maria Eugenia; de la Morena-Barrio, María Eugenia; Xiang, Yangfei; Patterson, Benjamin; Andersen, Elisabeth; Bravo-Pérez, Carlos; Kempf, Henning; Nordhus, Kathrine Sivertsen; Lunov, Oleg; Dejneka, Alexandr; Mowinckel, Marie-Christine; Stavik, Benedicte; Sandset, Per Morten; Melum, Espen; Baumgarten, Saphira Felicitas; Bonanini, Flavio; Kurek, Dorota; Mathapati, Santosh Sadashiv; Almaas, Runar; Sharma, Kulbhushan; Wilson, Steven Ray Haakon; Skottvoll, Frøydis Sved; Boger, Ida Caroline Sneis; Bogen, Inger Lise; Nyman, Tuula Anneli; Wu, Jun Jie; Bezrouk, Ales; Cizkova, Dana; Corral, Javier; Mokry, Jaroslav; Zweigerdt, Robert; Park, In-Hyun; Sullivan, Gareth John (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract The lack of physiological parity between 2D cell culture and in vivo culture has led to the development of more organotypic models, such as organoids. Organoid models have been developed for a number of tissues, ...