Browsing Kjemisk institutt by Author "Bogen, Inger Lise"

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  • Direct Electromembrane Extraction based Mass Spectrometry: A Tool for Studying Drug Metabolism Properties of Liver Organoids 
    Wilson, Steven Ray Haakon; Krauss, Stefan Johannes Karl; Lundanes, Elsa; Skottvoll, Frøydis Sved; Bogen, Inger Lise; Pedersen-Bjergaard, Stig; Hansen, Frederik; Aizenshtadt, Aleksandra; Kutter, Jörg P.; Andersen, Jannike Mørch; Martinez, Mikel Amirola (Journal article / Tidsskriftartikkel / PublishedVersion, 2021)
    This work introduces a strategy for organoid analysis - direct Electromembrane Extraction based Mass Spectrometry (dEME-MS) – for coupling liver organoids with mass spectrometry (MS). dEME-MS comprises electrophoresis of ...
  • Distinguishing Between Cyclopropylfentanyl and Crotonylfentanyl by Methods Commonly Available in the Forensic Laboratory 
    Bergh, Marianne Skov-Skov; Bogen, Inger Lise; Wohlfarth, Ariane; Wilson, Steven Ray Haakon; Øiestad, Åse Marit Leere (Journal article / Tidsskriftartikkel / SubmittedVersion, 2019)
    Background: The opioid analgesic fentanyl and its analogues pose a major health concern due to its high potency and the increasing number of overdose deaths worldwide. The analogues of fentanyl may differ in potency, ...
  • Electromembrane extraction and mass spectrometry for liver organoid drug metabolism studies 
    Skottvoll, Frøydis Sved; Hansen, Frederik; Harrison, Sean; Boger, Ida Caroline Sneis; Mrsa, Ago; Restan, Magnus Saed; Stein, Matthias; Lundanes, Elsa; Pedersen-Bjergaard, Stig; Aizenshtadt, Aleksandra; Krauss, Stefan; Sullivan, Gareth; Bogen, Inger Lise; Wilson, Steven Ray Haakon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Liver organoids are emerging tools for precision drug development and toxicity screening. We demonstrate that electromembrane extraction (EME) based on electrophoresis across an oil membrane is suited for segregating ...
  • "Organ-in-a-Column" Coupled On-line with Liquid Chromatography-Mass Spectrometry 
    Kogler, Stian; Aizenshtadt, Aleksandra; Harrison, Sean; Skottvoll, Frøydis Sved; Berg, Henriette Engen; Abadpour, Shadab; Scholz, Hanne; Sullivan, Gareth John; Thiede, Bernd; Lundanes, Elsa; Bogen, Inger Lise; Krauss, Stefan Johannes Karl; Røberg-Larsen, Hanne; Wilson, Steven Ray Haakon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Organoids, i.e., laboratory-grown organ models developed from stem cells, are emerging tools for studying organ physiology, disease modeling, and drug development. On-line analysis of organoids with mass spectrometry would ...
  • Scalable production of tissue-like vascularized liver organoids from human PSCs 
    Harrison, Sean Philip; Siller, Richard; Tanaka, Yoshiaki; Chollet Dugarte, Maria Eugenia; de la Morena-Barrio, María Eugenia; Xiang, Yangfei; Patterson, Benjamin; Andersen, Elisabeth; Bravo-Pérez, Carlos; Kempf, Henning; Nordhus, Kathrine Sivertsen; Lunov, Oleg; Dejneka, Alexandr; Mowinckel, Marie-Christine; Stavik, Benedicte; Sandset, Per Morten; Melum, Espen; Baumgarten, Saphira Felicitas; Bonanini, Flavio; Kurek, Dorota; Mathapati, Santosh Sadashiv; Almaas, Runar; Sharma, Kulbhushan; Wilson, Steven Ray Haakon; Skottvoll, Frøydis Sved; Boger, Ida Caroline Sneis; Bogen, Inger Lise; Nyman, Tuula Anneli; Wu, Jun Jie; Bezrouk, Ales; Cizkova, Dana; Corral, Javier; Mokry, Jaroslav; Zweigerdt, Robert; Park, In-Hyun; Sullivan, Gareth John (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract The lack of physiological parity between 2D cell culture and in vivo culture has led to the development of more organotypic models, such as organoids. Organoid models have been developed for a number of tissues, ...